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公开(公告)号：KR101232278B1
公开(公告)日：2013-02-12
申请号：KR1020110006214
申请日：2011-01-21
Applicant: 한국과학기술연구원
Abstract: 본 발명에 일 측면에 따르면, 손상된 신경의 기능을 복구하기 위한 신경 도관으로서, 상기 손상된 신경의 말단에 연결되는 지지체와, 상기 지지체의 몸체 내부로 형성되는 공동 형태의 채널과, 상기 채널의 내벽을 따라 형성되는 전극층 및 상기 전극층과 전기적으로 연결되는 외부 전극을 포함하고, 상기 절단된 신경의 말단에서 신경 세포가 상기 채널을 따라 성장하고, 상기 채널을 따라 성장한 신경 세포는 상기 전극층과 전기적으로 연결되는 신경 도관이 제공된다. 본 발명의 다른 측면에 따르면, 신경 도관을 이용한 신경 신호 검출 장치가 제공된다.
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公开(公告)号：KR100408458B1
公开(公告)日：2003-12-06
申请号：KR1020000082684
申请日：2000-12-27
Applicant: 한국과학기술연구원
IPC: A61L27/56
Abstract: Disclosed is a biocompatible medical material and porous scaffold for use in tissue engineering, made from a biodegradable glycolide/epsilon-caprolactone copolymer having a repeat unit of wherein x and y are integers greater than or equal to 18, the copolymer has an average molecular weight of about 10,000 daltons or more, and the molar ratio of glycolide: epsilon-caprolactone in the copolymer is about 4.0:6.0 to 6.0:4.0.
Abstract translation: 公开了一种用于组织工程的生物相容性医用材料和多孔支架，由具有重复单元的可生物降解的乙交酯/ε-己内酯共聚物制成，其中x和y是大于或等于18的整数，所述共聚物的平均分子量 约10,000道尔顿或更多，共聚物中乙交酯：ε-己内酯的摩尔比为约4.0:6.0至6.0:4.0。
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公开(公告)号：KR1020120084903A
公开(公告)日：2012-07-31
申请号：KR1020110006214
申请日：2011-01-21
Applicant: 한국과학기술연구원
CPC classification number: A61F2/04 , A61B5/04001 , A61L27/52 , H04B7/24
Abstract: PURPOSE: A neural tube and a neuron signal detecting system using the same are provided to perform a support function and a nerve electrode function. CONSTITUTION: A neural tube comprises a supporter(110) connected to the end of damaged nerve, a hollow channel(120) which is formed inside the body of the supporter, an electrode layer formed along the inner wall of the channel, and an outer electrode(130) which is electrically connected to the electrode layer. Nerve cells grow along the channel in the end of the damaged nerve. The nerve cell grown along the channel is electrically connected to the electrode layer. In the supporter, a plurality of channels is formed.
Abstract translation: 目的：提供神经管和使用其的神经元信号检测系统来执行支持功能和神经电极功能。 构成：神经管包括连接到受损神经末端的支撑件（110），形成在支撑体内部的中空通道（120），沿通道内壁形成的电极层 电极（130），其电连接到电极层。 神经细胞沿受损神经末端的通道生长。 沿着通道生长的神经细胞电连接到电极层。 在支持者中，形成多个通道。
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4.发明公开
公开(公告)号：KR1020020054061A
公开(公告)日：2002-07-06
申请号：KR1020000082684
申请日：2000-12-27
Applicant: 한국과학기술연구원
IPC: A61L27/56
Abstract: PURPOSE: A porous supporter for tissue engineering obtained from a copolymer of biodegradable glycolide/ε-caprolactone having excellent mechanical properties such as flexibility and elasticity and biodegradability is provided which can be effectively used as material for regenerating tissue of desired shapes. CONSTITUTION: This porous supporter is prepared from a biodegradable glycolide/ε -caprolactone copolymer having a recurring unit of formula 1 and a weight average molecular weight of 10,000. In formula, x and y are each 18 or more. The porous supporter has a pore size of 1 to 800 microns and a porosity of 50 to 99%.
Abstract translation: 目的：提供一种用于组织工程的多孔支持体，其由具有优异的机械性能如柔韧性和弹性和生物降解性的可生物降解的乙交酯/ε-己内酯的共聚物获得，其可以有效地用作用于再生所需形状的组织的材料。 构成：该多孔载体由具有式1的重复单元和重均分子量为10,000的可生物降解的乙交酯/ε-己内酯共聚物制备。 在式中，x和y分别为18以上。 多孔载体的孔径为1至800微米，孔隙率为50至99％。
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