Abstract:
The present invention relates to a method for determining the abnormality of a di-2-ethylhexyl phthalate metabolite excretion in a biological material by using the biological material. The purpose of the present invention is to provide the method for determining the abnormality of the di-2-ethylhexyl phthalate metabolite excretion in the biological material by using the molarity of phthalate metabolites.
Abstract:
본 발명은 분석대상 물질의 원소가 동위원소로 치환된 동위원소 물질을 내부 표준물질로 하여 분석대상 물질을 정량하는 단계; 상기 분석대상 물질 및 동위원소 물질을 할로겐알킬화하는 단계; 및 상기 할로겐알킬화된 분석대상 물질 및 동위원소 물질을 기체 크로마토그래피-이중 질량분석기에 주입하여 분석하는 단계;를 포함하는 산성제초제의 분석방법을 제공한다. 본 발명에 따르면, 동위원소 희석법을 통한 정량으로 인해 우수한 정밀도 및 정확도를 나타내고, 할로겐알킬화 단계를 통해 검출 감도를 향상시켜 산성제초제의 극미량 분석을 가능하게 하며, 이중질량분석기를 사용해 정량 분석함으로써 매질효과로 인한 바탕시료의 방해를 감소시켜 다양한 시료에 적용할 수 있다.
Abstract:
The present invention discloses a method for analyzing phthalate metabolites in biological samples, comprising the following steps of: performing enzyme decomposition of phthalate metabolites in a biological sample; performing trimethylsilylation of the decomposed phthalate metabolites; and performing quantitative analysis of the trimethylsilylated phthalate metabolites.
Abstract:
The present invention provides a method for analyzing acidic herbicides comprising: a step of quantifying analysis objects by using isotope materials in which the elements of the analysis objects are substituted with isotopes as internal standard materials; a step of performing halogen alkylation on the analysis objects and isotope materials; and a step of analyzing the halogen-alkylated analysis objects and isotope materials by injecting the halogen-alkylated analysis objects and isotope materials into a gas chromatography-tandem mass spectrograph. The present invention exhibits excellent precision and accuracy by quantification through an isotope dilution method, enables the analysis of the minimum quantity of acidic herbicides by increasing detection sensitivity through the halogen alkylation step and is able to be applied to various samples by performing quantitative analysis with a tandem mass spectrograph and reducing the disturbance of foundation samples due to medium effects.