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Patent Agency Ranking
公开(公告)号：KR1020020036817A
公开(公告)日：2002-05-16
申请号：KR1020020018412
申请日：2002-04-04
IPC: A61K31/47
Abstract: PURPOSE: A pharmaceutical composition containing tetrahydroisoquinoline compounds exhibiting an antiplatelet aggregation inhibiting action and iNOS inhibiting action except a cardiotonic action and blood pressure lowering action is provided which can be effectively as an agent for treatment of cardiac insufficiency. CONSTITUTION: This pharmaceutical composition contains as an effective component a compound selected from the group consisting of 1-α -naphtylmethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline represented by the formula 1 and 1-β-naphtylmethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline represented by the formula 2 and mixtures thereof.
Abstract translation: 目的：提供一种含有显示抗血小板聚集抑制作用的四氢异喹啉化合物和除了强心剂作用和降血压作用以外的iNOS抑制作用的药物组合物，其可以有效地用作治疗心功能不全的药剂。 构成：该药物组合物作为有效成分含有选自由式1表示的1-α-萘甲基-6,7-二羟基-1,2,3,4-四氢异喹啉和1-β-萘甲基 -6,7-二羟基-1,2,3,4-四氢异喹啉及其混合物。
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公开(公告)号：KR100352425B1
公开(公告)日：2002-09-11
申请号：KR1019990041208
申请日：1999-09-22
IPC: A61K31/47
CPC classification number: A61K31/472
Abstract: 본발명은하기화학식 1 및화학식 2로표시되는테트라하이드로이소퀴놀린 (tetrahydroisoquinoline)계화합물의새로운용도에관한것으로서, 이들화합물들은강심작용, 혈압강하작용외에도혈소판응집억제작용및 iNOS (유도 NO 합성효소) 억제작용을나타내므로이들을유효성분으로함유하는약학적조성물은심부전증치료제, 항혈전제, iNOS에의한조직손상억제제, 패혈증치료제또는파종성혈관내응고증의치료제로유용하게사용될수 있다.
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公开(公告)号：KR1020130020739A
公开(公告)日：2013-02-27
申请号：KR1020110081664
申请日：2011-08-17
Applicant: 한국과학기술연구원
IPC: C07D495/04 , H01L51/30
Abstract: PURPOSE: A donor-bridge-acceptor type organic semiconductor for a solar cell is provided to optimize a bridge structure and to enhance efficiency of the solar cell. CONSTITUTION: A donor-bridge-acceptor type organic semiconductor for a solar cell is denoted by chemical formula 1. In chemical formula 1, R1 and R2 are independently selected from hydrogen and C1-C20 saturated or unsaturated alkyl group of a straight chain or a branched chain. The organic semiconductor of chemical formula 1 is prepared according to reaction formula 1.
Abstract translation: 目的：提供用于太阳能电池的供体 - 桥 - 受体型有机半导体，以优化桥结构并提高太阳能电池的效率。 构成：化学式1表示用于太阳能电池的供体 - 桥 - 受体型有机半导体。在化学式1中，R 1和R 2独立地选自氢和C 1 -C 20饱和或不饱和的直链或 支链。 根据反应式1制备化学式1的有机半导体。
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公开(公告)号：KR1020000028711A
公开(公告)日：2000-05-25
申请号：KR1019990041208
申请日：1999-09-22
IPC: A61K31/47
CPC classification number: A61K31/472
Abstract: PURPOSE: Provided is a novel application of tetrahydroisoquinoline compound for a pharmaceutical composition, which could be used as a treatment for cardiac insufficiency, thrombosis, sepsis and/or disseminated intravascular coagulation(DIC). CONSTITUTION: Provided is a novel use of tetrahydroisoquinoline compounds which showcardiotonic and hypotensor effects, and suppression effects of platelet aggregation and iNOS(inducible NO syntheas) simultaneously in particular, a pharmaceutical composition comprising one or more of 1-alpha-naphthylmethy-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, and 1-beta-naphthylmethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoloine described in formula 1 and formula 2 respectively as available components is provided. The pharmaceutical compositions used as treatments for cardiac insufficiency such as infarction, chromic inflammation, hypertension, arteriosclerosis or congestive heart failure, thrombosis, sepsis and/or disseminated intravascular coagulation(DIC).
Abstract translation: 目的：提供四氢异喹啉化合物用于药物组合物的新型应用，可用于治疗心功能不全，血栓形成，败血症和/或弥散性血管内凝血（DIC）。 构成：提供了显示心力衰竭和低血压作用的四氢异喹啉化合物的新用途，特别是同时具有抑制血小板聚集和iNOS（诱导型NO合成）的作用的药物组合物，其包含1-α-萘基甲基-6,7 - 二羟基-1,2,3,4-四氢异喹啉和1-β-萘基甲基-6,7-二羟基-1,2,3,4-四氢异喹啉分别作为可得到的成分。 用作心脏功能不全的治疗药物组合物，如梗塞，铬炎症，高血压，动脉硬化或充血性心力衰竭，血栓形成，败血症和/或弥散性血管内凝血（DIC）。
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