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公开(公告)号：KR100378323B1
公开(公告)日：2003-03-29
申请号：KR1019990014356
申请日：1999-04-22
IPC: C07H13/08
CPC classification number: A61K31/704 , A61K36/69
Abstract: The present invention relates to psychotropic polygalasaponins and its extraction and isolation from the roots of Polygalae tenuifolia. The inhibitory activity of the extract from the roots of Polygalae tenuifolia on stereotyped behaviors and climbing behaviors induced by apomorphine was examined, and a single extract fraction that showed an activity particularly in behavioral pharmacology model was obtained from the roots of Polygalae tenuifolia. The object of the invention is therefore aimed at providing a new version of antipsychotic drug, polygalasaponic compound itself and a method to extract and isolate polygalasaponic compound from the roots of Polygalae Tenuifolia.
Abstract translation: 本发明涉及精神性多果皂苷及其从远志（Polygalae tenuifolia）根提取和分离。 研究了远志根部提取物对阿朴吗啡诱导的刻板行为和爬行行为的抑制活性，并从远志草的根部获得了一种特别在行为药理学模型中表现出活性的单一提取物部分。 因此，本发明的目的是提供一种新的抗精神病药物，多聚半乳糖化合物本身以及从远志藤根提取和分离多聚半乳糖化合物的方法。
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公开(公告)号：KR1020000066933A
公开(公告)日：2000-11-15
申请号：KR1019990014356
申请日：1999-04-22
IPC: C07H13/08
CPC classification number: A61K31/704 , A61K36/69
Abstract: PURPOSE: A psychotropic polygalasaponin based compound is provided which inhibits a stereotyped behavior and climbing behavior which are induced by apomorphine. CONSTITUTION: A psychotropic polygalasaponin is represented by formula 1 representation. An extraction method are characterized by comprising the following steps: (i)after grinding Polygalae Radix up to 70-230 mesh, extracting three times with 3-5 fold amount of alcohol solution; (ii)evaporating and condensing the filtrate at 70-76 cm Hg and at 60-70°C; (iii)after suspending the condensate in distilled water of 10 fold volume ratio, shaking the above thing by adding alcohol solvent of 1-2 fold and extracting three times and separating alcohol layer; (iv)condensing the above alcohol solvent fraction at 70-76 cmHg and at 60-70°C and obtaining an extract; (v)after suspending the above extract with distilled water of 50-100 fold adsorbing in resin HP-20 and draining active material with 70% methanol and condensing for obtaining an extract; (vi)after condensing the above extract with distilled water of 50-100 fold 2-3 times in common ratio, suspending homogeneously with same amount of distilled water and freeze-drying for obtaining a powder extract; (vii)dissolving the powder extract in ether and obtaining a precipitate;(viii)after saturating the precipitate with distilled water, passing through HP-20 resin and eluting an active site with methanol and adsorbing in silica gel and eluting active material by using ethyl acetate/methanol/water; (ix)adsorbing the active material in silica gel again and fractionating with mixed solvent of trichloro methane/methanol/ethanol/10%-acetic acid.
Abstract translation: 目的：提供一种精神分析多聚赖草皂苷的化合物，其抑制由阿朴吗啡诱导的定型行为和攀爬行为。 构成：精神分裂多糖分子由式1表示。 提取方法的特征在于包括以下步骤：（i）研磨多达70-230目后，用3-5倍量的醇溶液萃取三次; （ii）在70-76cm Hg和60-70℃下蒸发并冷凝滤液; （iii）将冷凝物悬浮在10倍体积比的蒸馏水中后，加入1-2倍的酒精溶剂振荡上述物质，萃取3次，分离醇层; （iv）将上述醇溶剂级分在70-76cmHg和60-70℃下冷凝并得到提取物; （v）将吸附在树脂HP-20中的50-100倍的蒸馏水悬浮在上述提取物上，并用70％甲醇排出活性物质并冷凝得到提取物; （vi）将上述提取物与常规比例为50-100倍的蒸馏水冷凝2-3次后，用相同量的蒸馏水均匀悬浮，冷冻干燥得到粉末提取物; （vii）将粉末提取物溶解在乙醚中并获得沉淀物;（viii）在用蒸馏水使沉淀物饱和后，通过HP-20树脂并用甲醇洗脱活性位点并吸附在硅胶中，并用乙基 乙酸乙酯/甲醇/水; （ix）再次将活性物质吸附在硅胶中，并用三氯甲烷/甲醇/乙醇/ 10％乙酸的混合溶剂进行分馏。
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公开(公告)号：KR1020160088711A
公开(公告)日：2016-07-26
申请号：KR1020150008132
申请日：2015-01-16
Applicant: 한국과학기술연구원
IPC: G02B27/01
CPC classification number: G02B27/0176
Abstract: 표정모니터링또는립 리딩을위한헤드마운트형카메라장치는, 사용자의머리에고정되는머리고정모듈과, 상기머리고정모듈에대해회동가능하게연결되는카메라고정모듈과, 스테레오카메라를포함하고, 상기카메라고정모듈에결합되어상기사용자의얼굴앞쪽에배치되는카메라모듈및 상기머리고정모듈에대한상기카메라고정모듈의위치를선택적으로고정시킬수 있는잠금모듈을포함한다.
Abstract translation: 用于面部表情监测或唇读的头戴式相机装置包括固定到用户头部的热定影模块和可旋转地连接到头部固定模块的相机固定模块，以及包括立体声的相机模块 照相机与相机固定模块组合，并且布置在用户面部的前面，以及锁定模块，其可以选择性地固定用于热定影模块的相机固定模块的位置。 因此，头戴式相机装置可用于严重残疾人士。
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公开(公告)号：KR101651537B1
公开(公告)日：2016-08-26
申请号：KR1020150118548
申请日：2015-08-24
Applicant: 한국과학기술연구원
IPC: A61B5/0404 , A61B5/00
CPC classification number: A61B5/0402 , A61B5/0006 , A61B5/6824 , A61B5/6828 , A61B5/6829 , A61B5/6831 , A61B5/7225 , A61B5/725 , A61B5/7278 , A61B5/742 , A61B5/7475
Abstract: 무선통신을이용하여서로연결되는제1 측정장치및 제2 측정장치를포함하는, 무선통신을이용한심전도측정장치에있어서, 상기제1 측정장치는심장박동에의해생성된제1 신호를측정하는제1 전극및 상기제1 신호및 상기제2 측정장치로부터수신한무선가상접지신호를기초로슬레이브신호를생성하는슬레이브신호생성부를포함하고, 상기제2 측정장치는심장박동에의해생성된제2 신호를측정하는제2 전극, 접지신호를측정하는접지전극, 상기접지신호를기초로상기무선가상접지신호를생성하는무선가상접지부및 상기슬레이브신호, 상기제2 신호및 상기무선가상접지신호를기초로심전도를측정하는심전도측정부를포함하는, 무선통신을이용한심전도측정장치.
Abstract translation: 本发明涉及一种使用无线通信测量心电图的装置，其包括使用无线通信彼此连接的第一测量装置和第二测量装置。 第一测量装置包括测量由心跳产生的第一信号的第一电极和基于第一信号产生从属信号的从信号产生单元和从第二测量装置接收的无线虚拟接地信号。 第二测量装置包括测量由心跳产生的第二信号的第二电极，测量接地信号的接地电极，基于接地信号产生无线虚拟接地信号的无线虚拟接地单元和基于心电图的心电图测量单元 在从机信号上，第二信号和无线虚拟接地信号。
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