公开(公告)号：KR101373755B1

公开(公告)日：2014-03-14

申请号：KR1020120107322

申请日：2012-09-26

Applicant: 한국과학기술연구원 ,  씨에스아이알

Inventor： 양현옥 ,  정성권 ,  권학철 ,  차진욱 ,  김영주 ,  제르다포우체 ,  루드자니느탐벨레니 ,  다쉬니에나이두 ,  제레미아세나베 ,  빈네쉬자이찬드마하라이 ,  에릭크홀롬비 ,  함정엽 ,  김준기

IPC: A61K31/36 ,  A61K31/343 ,  A61P25/28 ,  A61P25/00

CPC classification number: A61K31/365 ,  A23L2/52 ,  A23L33/105 ,  A61K36/185

Abstract: Provided is a composition containing arylnaphthalene lignan derivatives, that are one or more selected from a group consisting of Justicidin A, 5-methoxyjusticidin A, Chinensinaphtol, and a pharmaceutically acceptable salt thereof as an active ingredient for preventing, relieving, and/or treating dementia, and ameliorating memory impairment and/or improving memory.

Abstract translation: 本发明提供一种含有芳基萘木酚素衍生物的组合物，其为选自由作为预防，缓解和/或治疗痴呆的活性成分的作为组合的正好小儿群A，5-甲氧基调节蛋白A， ，并改善记忆障碍和/或改善记忆。

公开(公告)号：KR101360143B1

公开(公告)日：2014-02-11

申请号：KR1020120107323

申请日：2012-09-26

Applicant: 한국과학기술연구원 ,  씨에스아이알

Inventor： 양현옥 ,  정성권 ,  권학철 ,  차진욱 ,  빈네쉬자이찬드마하라이 ,  루드자니느탐벨레니 ,  다쉬니에나이두 ,  김영주 ,  함정엽 ,  제레미아세나베 ,  제르다포우체 ,  에릭크홀롬비 ,  김준기

IPC: A61K36/185 ,  A61K36/18 ,  A61P25/28 ,  A61P25/00

CPC classification number: A61K36/185 ,  A23L2/52 ,  A23L33/105 ,  A61K2236/39

Abstract: The present invention relates to a pharmaceutical composition for preventing and/or treating dementia comprising extracts of Monsonia species; a food composition for preventing and/or inhibiting dementia comprising extracts of Monsonia species; and a method of preparing an extract of Monsonia species with excellent inhibitory effect on the formation of beta-amyloid. The plant extract can inhibit the formation of beta-amyloid which has been known as a factor causing the dementia, especially Alzheimer's disease, thereby being used for preventing, inhibiting, and/or treating the dementia.

Abstract translation: 本发明涉及一种用于预防和/或治疗痴呆症的药物组合物，其包括松香种类的提取物; 一种用于预防和/或抑制痴呆症的食物组合物，其包括松属物种的提取物; 以及制备具有对β-淀粉样蛋白形成具有优异抑制作用的松香种提取物的方法。 植物提取物可以抑制已知作为引起痴呆的因素，特别是阿尔茨海默氏病的β-淀粉样蛋白的形成，从而用于预防，抑制和/或治疗痴呆症。