Abstract:
The present invention relates to a pharmaceutical composition for preventing and/or treating dementia comprising extracts of Monsonia species; a food composition for preventing and/or inhibiting dementia comprising extracts of Monsonia species; and a method of preparing an extract of Monsonia species with excellent inhibitory effect on the formation of beta-amyloid. The plant extract can inhibit the formation of beta-amyloid which has been known as a factor causing the dementia, especially Alzheimer's disease, thereby being used for preventing, inhibiting, and/or treating the dementia.
Abstract:
Provided is a composition containing arylnaphthalene lignan derivatives, that are one or more selected from a group consisting of Justicidin A, 5-methoxyjusticidin A, Chinensinaphtol, and a pharmaceutically acceptable salt thereof as an active ingredient for preventing, relieving, and/or treating dementia, and ameliorating memory impairment and/or improving memory.
Abstract:
올레아노닉산(oleanonic acid)의 치매 예방 및/또는 치료 용도에 관한 것이다. 올레아노닉산은 치매, 특히 알츠하이머병의 원인물질로 알려진 베타-아밀로이드의 생성을 억제할 수 있어서, 치매를 포함하는 퇴행성 신경질환의 예방 및/또는 치료에 효과적으로 사용될 수 있다.
Abstract:
PURPOSE: A composition containingi oleanonic acid for preventing or treating dementia is provided to suppress beta-amyloid generation. CONSTITUTION: A composition for preventing or treating neurodegenerative diseases contains oleanonic acid of chemical formula 1 or pharmaceutically acceptable salt thereof as an active ingredient. A composition for preventing or treating neurodegenerative diseases contains Patrinia scabiosaefolia extract, dried material of the extract, or concentrate of the extract as an active ingredient. The Patrinia scabiosaefolia extract is isolated using water or alcohol of C1-C4.
Abstract:
본 발명은 용안육 추출물, 또는 용안육이 포함된 혼합 추출물을 함유하는 퇴행성 뇌신경질환의 예방 또는 치료용 조성물에 관한 것으로, 본 발명의 조성물은 용안육 추출물 또는 용안육이 포함된 혼합 추출물을 유효성분으로 함유함으로써, 퇴행성 뇌신경질환의 예방 또는 치료 효과가 현저히 우수하며 특히 본 발명의 조성물은 도파민성 신경계에 선택적 작용을 하는 MPTP에 의한 신경 독성과 알파-시누클레인(alpha-synuclein) 단백질 응집에 의한 신경 독성으로부터 도파민 신경세포를 유의성 있게 보호함으로써 퇴행성 뇌신경질환을 효과적으로 예방 또는 치료할 수 있다.
Abstract:
PURPOSE: A composition containing Longan arillus extract or mixture extract thereof is provided to protect dopaminergic neuron and to effectively prevent or treat neurodegenerative diseases. CONSTITUTION: A pharmaceutical composition for preventing or treating neurodegenerative diseases contains Longan arillus extract as an active ingredient. The pharmaceutical composition additionally contains Angelicae tenuissimae radix or Polygalaceae extract. The pharmaceutical composition also contains Pueraria lobata (Willd.) Ohwi, Scutellariae Radix, Platycodi Radix, Angelica dahurica Bentham et Hooker, Cimicifugae Rhizoma, Raphanus sativus L. or Acori Gramineri Rhizoma. The extract is isolated using water, low alcohol of C1-C4, hexane, methylene chloride, acetonitrile or acetone organic solvent, or mixture thereof. A food composition for preventing or treating neurodegenerative diseases contains Longan arillus extract as an active ingredient.