-
公开(公告)号：WO2015199435A1
公开(公告)日：2015-12-30
申请号：PCT/KR2015/006409
申请日：2015-06-24
Applicant: 한국생명공학연구원
Abstract: 본 발명은 RpSTS 단백질을 코딩하는 유전자를 포함하는 재조합 벡터로 형질전환된 식물체 및 IbMYB1a 단백질을 코딩하는 유전자를 포함하는 재조합 벡터로 형질전환된 식물체를 교배하여 RpSTS 유전자 및 IbMYB1a 유전자를 동시에 과발현하는 야생형에 비해 스틸벤 생산이 증가된 형질전환 식물체의 제조 방법, 상기 방법에 의해 제조된 형질전환 식물체에 관한 것으로, 다양한 유용 생리활성을 가진 스틸벤 화합물을 다양한 식물체에서 대량으로 생산하는 것이 훨씬 용이해질 것으로 기대된다.
Abstract translation: 本发明涉及：与野生型相比，过表达RpSTS基因和IbMYB1a基因的野生型相比，通过与已经用含有 编码RpSTS蛋白的基因，其中植物已经用含有编码IbMYB1a蛋白的基因的重组载体转化; 和通过该方法制备的转基因植物。 预期在各种植物中大规模生产具有各种有用生理活性的二苯乙烯化合物将变得容易得多。
-
公开(公告)号：WO2013058582A2
公开(公告)日：2013-04-25
申请号：PCT/KR2012/008560
申请日：2012-10-18
Applicant: 한국생명공학연구원
IPC: C12P19/18 , C12P17/10 , C12P19/26 , C07D225/06
CPC classification number: C07D225/06 , C07D405/12 , C07D405/14 , C12P19/18 , C12P19/62
Abstract: 본 발명은 당전이 효소를 이용한 안사마이신 배당체 또는 안사마이신 골격을 갖는 비-벤조퀴논 젤다나마이신 배당체의 제조방법, 비-벤조퀴논 젤다나마이신 배당체 및 이를 유효성분으로 함유하는 암 질환 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 발명은 안사마이신 또는 안사마이신 골격을 갖는 비-벤조퀴논 젤다나마이신 화합물에 글루코실기를 도입함으로써, 용해도가 상승하고, 생체 내 이용률을 높일 수 있으며, 안사마이신계 화합물의 활성을 유지하므로 항생제, 항진균제, 항바이러스제, 면역억제제, 퇴행성 신경질환제, 항염증제 또는 항암제로 유용하게 사용될 수 있다.
Abstract translation:
本发明阿齐霉素安萨里糖苷或安萨里红霉素骨架具有非被dangjeon用酶对苯醌格尔德霉素糖苷和的这种活性成分苯醌格尔德霉素糖苷的制造方法，非 涉及包含癌症预防或治疗，本发明的药物组合物是阿奇霉素安萨里或具有通过在苯醌格尔德霉素化合物，溶解度增加，体内利用的导入葡糖基的雷帕霉素骨架安萨里比 可以增加，维持化合物安萨里我新界的活性，所以可以用作抗生素，抗真菌剂，抗病毒剂，免疫抑制剂，神经变性疾病剂，抗炎剂或抗癌剂。有用
-
公开(公告)号：KR101566692B1
公开(公告)日：2015-11-09
申请号：KR1020140078621
申请日：2014-06-26
Applicant: 한국생명공학연구원
CPC classification number: A01H5/00 , A01H5/10 , C12N9/00 , C12N15/09 , C12Q1/6827
Abstract: 본발명은 RpSTS 단백질을코딩하는유전자를포함하는재조합벡터로형질전환된식물체및 IbMYB1a 단백질을코딩하는유전자를포함하는재조합벡터로형질전환된식물체를교배하여유전자및유전자를동시에과발현하는야생형에비해스틸벤생산이증가된형질전환식물체의제조방법, 상기방법에의해제조된형질전환식물체에관한것으로, 다양한유용생리활성을가진스틸벤화합물을다양한식물체에서대량으로생산하는것이훨씬용이해질것으로기대된다.
Abstract translation: 本发明涉及一种能够产生比野生型对应物更多量增加的转基因植物的方法，该野生型对应物同时过表达RpSTS基因和IbMYB1a基因，通过交叉施用由重组体转化的植物 载体，其包含编码RpSTS蛋白的基因和由包含编码IbMYB1a蛋白的基因的重组载体转化的植物。 此外，本发明还涉及通过该方法生产的转基因植物。 预期在各种植物中大规模生产具有各种有用生物活性的二苯乙烯化合物变得更加容易。
-
公开(公告)号：KR1020140146307A
公开(公告)日：2014-12-26
申请号：KR1020130068749
申请日：2013-06-17
Applicant: 한국생명공학연구원
IPC: A61K31/19 , A61K31/191 , A61P31/04
CPC classification number: Y02A40/78
Abstract: The present invention relates to an antibacterial composition containing ursolic acid as an active ingredient for inhibiting livestock pathogenic bacteria, especially, to an antibacterial composition for inhibiting Actinobacillus pleuropneumoniae, Pasteurella multocida A, or Pasteurella multocida D, which is a pathogen causing porcine respiratory disease complex, and to a livestock feed additive and livestock feed containing the composition as an active ingredient. The antibacterial composition containing ursolic acid as an active ingredient for inhibiting livestock pathogenic bacteria of the present invention can be utilized as alternative antibiotics, and can be industrially very useful since the ursolic acid is mass-produced in the process of producing apple or persimmon processed products but mostly produced from peels, which are just discarded byproducts.
Abstract translation: 本发明涉及含有熊果酸作为抑制家畜病原菌的活性成分的抗菌组合物，特别涉及用于抑制胸膜肺炎放线杆菌，多杀巴斯德氏菌多巴胺或多巴氏杆菌D的抗菌组合物，其是引起猪呼吸道疾病复合物的病原体 ，以及含有组合物作为活性成分的家畜饲料添加剂和家畜饲料。 含有熊果酸作为本发明的家畜病原菌活性成分的抗菌组合物可以用作替代抗生素，并且在工业上可以非常有用，因为在生产苹果或柿子加工产品的过程中大量生产熊果酸 但大多是由剥离产生的，它们只是被废弃的副产物。
-
公开(公告)号：KR1020140050314A
公开(公告)日：2014-04-29
申请号：KR1020120116565
申请日：2012-10-19
Applicant: 한국생명공학연구원
CPC classification number: C12P17/06
Abstract: The present invention relates to a production method of quercetin or isoquercitrin from quercetin glucoside using β-glucosidase (EC 3.2.1.21) derived from Aspergillus niger (deposition number KCTC 6906): which is simple without complex processes compare to existing methods of biologically converting into quercetin or isoquercitrin using a chemical technique or enzymes or increasing the content of flavonoid of the quercetin, etc. using infrared rays; and uses onion, which can be easily obtained from the market, as a raw material for an enzyme reaction of the quercetin glucoside abundantly contained in the onion, thereby economically producing the quercetin or isoquercitrin. [Reference numerals] (AA) Reaction time : 0 hour; (BB) Formula 2; (CC) Reaction time : 2 hours; (DD) Quercetin
Abstract translation: 本发明涉及使用源于黑曲霉（沉积数KCTC 6906）的β-葡糖苷酶（EC 3.2.1.21）从槲皮素葡萄糖苷生产槲皮素或异槲皮素的制备方法：与现有的生物转化方法相比，其简单无复杂过程 槲皮素或异槲皮素，使用化学技术或酶，或使用红外线增加槲皮素等的类黄酮含量; 并且使用可以容易地从市场获得的洋葱作为大量含有的槲皮素葡萄糖苷的酶反应的原料，从而经济地生产槲皮素或异槲皮素。 （标号）（AA）反应时间：0小时; （BB）式2; （CC）反应时间：2小时; （DD）槲皮素
-
Patent Agency Ranking
公开(公告)号：KR1020130054478A
公开(公告)日：2013-05-27
申请号：KR1020110117365
申请日：2011-11-11
Applicant: 대한민국(농촌진흥청장) , 한국생명공학연구원
CPC classification number: C12N15/825 , A23K10/30 , C07K14/415 , C12N15/8205 , C12N15/8257
Abstract: PURPOSE: A system for preparing a large amount of anthocyanin is provided to develop a health functional food industry, a cosmetic industry, a medical product industry, and a dye industry. CONSTITUTION: IbMYB1a gene has a base sequence of sequence number 1. A method for producing a transgenic plant with enhanced anthocyanin content comprises: a step of transforming a plant cell with a recombinant vector containing Ipomoea batatas-derived IbMYB1a gene; and a step of redifferentiating a plant from the plant cells. The plant is dicotyledones. A composition for enhancing anthocyanin in a plant contains IbMYB1a gene.
Abstract translation: 目的：提供一种制备大量花青素的系统，用于开发健康功能食品工业，化妆品工业，医疗产品工业和染料工业。 构成：IbMYB1a基因具有序列号1的碱基序列。具有增加的花青素含量的转基因植物的制备方法包括：用含有番薯as源的IbMYB1a基因的重组载体转化植物细胞的步骤; 以及从植物细胞重新分配植物的步骤。 植物是双子叶植物。 用于增强植物中花青素的组合物含有IbMYB1a基因。
-
公开(公告)号：KR101012503B1
公开(公告)日：2011-02-08
申请号：KR1020080121097
申请日：2008-12-02
Applicant: 한국생명공학연구원
Abstract: 본 발명은 방사선 조사에 의한 에르고칼시페롤(ergocalciferol)의 제조 방법에 관한 것으로, 보다 상세하게는 비타민 D의 전구체인 에르고스테롤(ergosterol)에 감마선을 조사하여 비타민 D 중 가장 생리활성이 높은 에르고칼시페롤로 전환시키는 방법에 관한 것이다. 본 발명의 감마선을 조사하여 에르고스테롤로부터 에르고칼시페롤로 전환하는 방법은 농수축산물 원료 또는 가공식품들의 살균 또는 살충 효과와 함께 비타민 D인 에르고칼시페롤의 함량을 증대시켜 비타민 D 결핍 질환 예방 및 치료에 유용하게 사용될 수 있다.
에르고스테롤, 방사선, 에르고칼시페롤, 비타민 D.-
公开(公告)号：KR1020100137852A
公开(公告)日：2010-12-31
申请号：KR1020090056088
申请日：2009-06-23
Applicant: 한국생명공학연구원
IPC: A61K36/8962 , A61P3/04 , A23L1/30
Abstract: PURPOSE: A composition containing black onion extract for preventing and treating obesity is provided to control body weight and used in a drug and functional food additive. CONSTITUTION: A pharmaceutical composition for preventing and treating obesity contains black onion extract as an active ingredient. The black onion extract is isolated using water, alcohol or mixture thereof. The pharmaceutical composition is manufactured in the form of powder, tablet, capsule, pill or granule. A food additive for preventing and treating obesity contains black onion extract as an active ingredient. The food additive is seasoning, wheat flour, milk product, or beverage.
Abstract translation: 目的：提供含有用于预防和治疗肥胖的黑洋葱提取物的组合物以控制体重并用于药物和功能性食品添加剂中。 构成：用于预防和治疗肥胖症的药物组合物含有黑洋葱提取物作为活性成分。 使用水，酒精或其混合物分离黑洋葱提取物。 药物组合物以粉末，片剂，胶囊，丸剂或颗粒剂的形式制备。 用于预防和治疗肥胖症的食品添加剂含有黑洋葱提取物作为活性成分。 食品添加剂是调味料，小麦粉，牛奶制品或饮料。
-
公开(公告)号：KR1020100122309A
公开(公告)日：2010-11-22
申请号：KR1020090041290
申请日：2009-05-12
Applicant: 한국생명공학연구원
IPC: A61K36/605 , A61P19/06 , A23L1/30
CPC classification number: A61K36/605 , A23L33/105 , A61K2236/33
Abstract: PURPOSE: A composition containing mulberry extract for preventing and treating grout or hyperuricemia is provided to use as a drugs and functional foods. CONSTITUTION: A composition for preventing and treating gout or hyperuricemia contains mulberry extract as an active ingredient. The mulberry extract is isolated using water, alcohol or mixture thereof. The alcohol is low alcohol of C1-C4. The low alcohol is ethanol or methanol. A functional food for preventing and relieving grout or hyperuricemia contains mulberry extract as an active ingredient.
Abstract translation: 目的：提供含有桑树提取物，用于预防和治疗灌浆或高尿酸血症的组合物，用作药物和功能性食品。 构成：用于预防和治疗痛风或高尿酸血症的组合物含有桑叶提取物作为活性成分。 使用水，醇或其混合物分离桑叶提取物。 醇是C1-C4的低醇。 低级醇是乙醇或甲醇。 用于预防和缓解灌浆或高尿酸血症的功能性食品含有桑叶提取物作为活性成分。
-
10.发明公开복분자 추출물을 유효성분으로 포함하는 통풍 또는 고요산혈증 예방 및 치료용 조성물 无效用于预防和治疗GOUT或HYPERURMIMIMIA的RUBUS COREANUS MIUEL提取物的组合物
公开(公告)号：KR1020100122308A
公开(公告)日：2010-11-22
申请号：KR1020090041289
申请日：2009-05-12
Applicant: 한국생명공학연구원
CPC classification number: A61K36/73 , A61K2236/331 , A61K2236/333 , Y10S514/825
Abstract: PURPOSE: A composition containing Rubus coreanus Miquel extract for preventing and treating gout or hyperuricemia is provided to use in drugs and functional food. CONSTITUTION: A composition for preventing and treating gout or hyperuricemia contains Rubus coreanus Miquel extract as an active ingredient. The Rubus coreanus Miquel extract is isolated using water, alcohol or mixture thereof. The alcohol is low alcohol of C1-C4. The low alcohol is ethanol or methanol. A functional food for preventing and treating gout or hyperuricemia contains Rubus coreanus Miquel extract as an active ingredient.
Abstract translation: 目的：提供用于预防和治疗痛风或高尿酸血症的含有Rubus coreanus Miquel提取物的组合物用于药物和功能性食物。 构成：用于预防和治疗痛风或高尿酸血症的组合物含有作为有效成分的芦荟提取物。 使用水，酒精或其混合物分离红曲霉提取物。 醇是C1-C4的低醇。 低级醇是乙醇或甲醇。 用于预防和治疗痛风或高尿酸血症的功能性食品含有作为活性成分的芦荟提取物。
-
-
-
-
-
-
-
-
-
Search Results
101
records
(took 0.027 seconds)
