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公开(公告)号：KR1020130112969A
公开(公告)日：2013-10-15
申请号：KR1020120030557
申请日：2012-03-26
Applicant: 한국식품연구원
IPC: A61K35/618 , A23L1/30 , A61K38/01 , C07K5/08
CPC classification number: A61K35/618 , A23L33/10 , A61K38/012 , C07K5/08
Abstract: PURPOSE: A pharmaceutical composition and a health food for suppressing angiotensin-converting enzyme (ACE) are provided to prevent and treat hypertension. CONSTITUTION: A pharmaceutical composition for suppressing ACE contains an extract or a hydrolysate of comb pen shells. The enzyme is protamex. The hydrolysate is an extract or a purified material of a comb pen shell hydrolysate. A health food for suppressing ACE contains the extract or the hydrolysate as an active ingredient.
Abstract translation: 目的：提供一种用于抑制血管紧张素转换酶（ACE）的药物组合物和保健食品，用于预防和治疗高血压。 构成：用于抑制ACE的药物组合物含有梳子笔壳的提取物或水解物。 酶是protamex。 水解产物是梳状笔壳水解产物的提取物或纯化材料。 用于抑制ACE的保健食品含有提取物或水解产物作为活性成分。
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公开(公告)号：KR1020120019045A
公开(公告)日：2012-03-06
申请号：KR1020100082144
申请日：2010-08-24
Applicant: 한국식품연구원
Abstract: PURPOSE: A functional composition containing Akiami paste shrimp extract is provided to suppress adipocyte differentiation in a human body and PPAR-gamma transcription. CONSTITUTION: A method for preparing a functional composition containing Akiami paste shrimp extract for anti-obesity comprises: a step of adding 0.1%(v/v) of protease to Akiami paste shrimp and hydrolyzing at 55°C for 2 hours; a step of heating the mixture at 100°C for 10 minutes and inactivating the protease; and a step of cooling the mixture and centrifuging to isolate supernatant. A functional composition for anti-obesity contains the extract.
Abstract translation: 目的：提供含有秋叶酱虾提取物的功能组合物，以抑制人体脂肪细胞分化和PPAR-γ转录。 构成：含有用于抗肥胖的秋叶糊虾提取物的功能组合物的方法包括：向秋叶酱虾中加入0.1％（v / v）的蛋白酶并在55℃下水解2小时的步骤; 在100℃下加热混合物10分钟并使蛋白酶失活的步骤; 和冷却混合物并离心以分离上清液的步骤。 用于抗肥胖的功能组合物含有提取物。
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公开(公告)号：KR101497506B1
公开(公告)日：2015-03-03
申请号：KR1020120030557
申请日：2012-03-26
Applicant: 한국식품연구원
IPC: A61K35/618 , A23L1/30 , A61K38/01 , C07K5/08
Abstract: 본 발명은 키조개 추출물 또는 키조개의 효소 가수분해물을 유효성분으로 포함하는 것을 특징으로 하는 안지오텐신 전환효소(Angiotensin-I converting enzyme: ACE) 저해제 및 이의 제조방법을 제공한다. 또한, 안지오텐신 전환효소 저해 활성을 지닌 펩타이드의 구조를 제공한다. 본 발명에 따른 안지오텐신 전환효소 저해용 약학 조성물 및 건강기능식품은 고혈압의 예방 및 치료에 사용될 수 있다.
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