Abstract:
본 발명은 청호 (Artemisia apiaceae) 추출물, 팔각회향 (Illicium verum) 추출물 및 정력자 (Lepidium apefalum) 추출물로 구성된 군으로부터 선택되는 하나 또는 둘 이상의 식물 추출물을 유효성분으로 포함하는 기억력 또는 학습 능력 증진용 조성물 및 인지기능장애 예방 및 치료용 조성물에 관한 것이다. 본 발명은 아세틸콜린스테라아제의 활성을 억제, 항산화 활성(예컨대, 활성산소종) 및 NMDA 리셉터와의 친화력을 통하여 신경세포, 특히 대뇌 기저부의 신경세포의 손상을 억제시킬 수 있는 효과를 가진다. 본 발명은 신경세포를 보호 및 손상의 예방 효과를 통하여 기억력 또는 학습 능력을 증진시킬 수 있을 뿐 만 아니라 인지기능장애로 질환을 예방 및 치료 할 수 있는 효능을 발휘한다. 또한, 본 발명은 기억력 또는 학습 능력의 증진 효능, 또는 인지기능장애를 예방 및 치료 효능을 가지는 정력자 추출물의 의약 및 식품으로서의 기초적인 자료를 제공한다.
Abstract:
The present invention relates to a composition comprising at least one selected from the group consisting of Curcuma xanthorrhizae extract, curcumin, demethoxycurcumin, and xanthorrhizol for improving memory and learning ability. The composition of the present invention particularly has an effect of suppressing damage of nerve cells in cerebrum fundus by inhibiting activity of acetylcholinesterase. In addition, the composition of the present invention not only can improve memory and learning ability via effects of nerve cell protection and damage prevention, but also can prevent and treat cognitive disorders.
Abstract:
PURPOSE: A composition for memory ability and study ability enhancement with one or more selected from a group of Curcuma xanthorrhizae extract, curcumin, dimethoxy curcumin, and xanthorrihizol is provided to curb damage in a nerve cell, especially in a nerve cell of cerebrum base, through suppressing vitality of Acetylcholinesterase. CONSTITUTION: Composition for memory ability and study ability enhancement contains one or more selected from a group of Curcuma xanthorrhizae extract, curcumin, dimethoxy curcumin, and xanthorrihizol. The composition suppresses vitality of Acetylcholinesterase. A cognitive impairment is dementia, learning disability, agnosia, or delirium. A food composition for memory ability and study ability enhancement contains one or more selected from a group of Curcuma xanthorrhizae extract, curcumin, dimethoxy curcumin, and xanthorrihizol. A medicinal composition for prevention or treatment of cognitive impairment contains (a) a therapeutic effective dose of the component; and (b) a carrier allowed in pharmacology.
Abstract:
PURPOSE: A pharmaceutical composition containing Polygonum multiflorum extract for lowering blood pressure is provided to prevent and treat hypertension. CONSTITUTION: A pharmaceutical composition for reducing blood pressure contains Polygonum multiflorum ethanol extract as an active ingredient. The ethanol is 70-90% ethanol. A functional food with an activity of reducing blood pressure contains Polygonum multiflorum ethanol extract as an active ingredient. A pharmaceutical composition for reducing blood pressure contains 0.02-50 wt% of the Polygonum multiflorum extract. The pharmaceutical composition is manufactured in the form of powder, granules, tablets, capsules, suspension, emulsion, syrup, external use formulation, and suppository.
Abstract:
PURPOSE: A pharmaceutical composition containing Cynanchum wilfordii extract for reducing blood cholesterol is provided to prevent and treat hypercholesterolemia. CONSTITUTION: A pharmaceutical composition for reducing blood cholesterol contains 0.02-50 wt% of Cynanchum wilfordii ethanol extract as an active ingredient. The ethanol is 70-90% ethanol. The Cynanchum wilfordii ethanol extract is prepared by washing, drying, and pulverizing Cynanchum wilfordii and extracting at 90-98°C for five to seven hours, and concentrating. The pharmaceutical composition is manufactured in the form of powder, granules, tablets, capsules, suspension, emulsion, syrup, external use formulation, and suppository.
Abstract:
본 발명은 적하수오 추출물을 포함하는 혈중 콜레스테롤 저하용 약학 조성물에 관한 것으로, 더욱 상세하게 본 발명은 적하수오( Polygonum
multiflorum ) 에탄올 추출물을 포함하는 혈중 콜레스테롤 저하용 약학 조성물, 적하수오를 세척, 건조 및 분쇄하고, 70 ~ 90% 에탄올을 가해 초고속 진공 저온 추출기로 90 ~ 98℃에서 5 ~ 7 시간 동안 추출한 후 농축하는 방법에 의해 수득되는 적하수오 에탄올 추출물의 제조방법 및 적하수오 에탄올 추출물을 포함하는 혈중 콜레스테롤 저하 활성을 갖는 기능성 식품을 제공한다.
Abstract:
PURPOSE: A pharmaceutical composition containing Polygonum multiflorum extract for reducing blood cholesterol is provided to prevent and relieve hypercholesterolemia. CONSTITUTION: A pharmaceutical composition for reducing blood cholesterol contains 0.02-50 wt% of Polygonum multiflorum ethanol extract as an active ingredient. The ethanol extract of Polygonum multiflorum is prepared by washing, drying, and pulverizing Polygonum multiflorum, isolating with a ultrahigh speed vacuum extractor of low temperature at 90-98°C for 5-7 hours, and concentrating. A functional food with activity of reducing blood cholesterol contains the ethanol extract as an active ingredient. The pharmaceutical composition is used in the form of powder, granules, tablets, capsules, suspension, emulsion, syrup, or sterilization injection solution.
Abstract:
PURPOSE: A pharmaceutical composition containing Cynanchum wilfordii extract is provided to reduce blood pressure and to prevent and treat hypertension. CONSTITUTION: A pharmaceutical composition for reducing blood pressure contains Cynanchum wilfordii ethanol extract as an active ingredient. A functional food with an activity of reducing blood pressure contains 0.02-50 wt% of the Cynanchum wilfordii ethanol extract as an active ingredient. The pharmaceutical composition is manufactured in the form of powder, granules, tablets, capsules, suspension, emulsion, syrup, external use formulation, supporsitory, and sterilization injection solution. The Cynanchum wilfordii extract is administered in 0.0001-100mg/kg a day.
Abstract:
PURPOSE: A pharmaceutical composition containing Cynanchum wilfordii extract for reducing blood clot is provided to prevent and relieve heart diseases and stroke. CONSTITUTION: A pharmaceutical composition for reducing blood clot contains 0.02-50 wt% of Cynanchum wilfordii ethanol extract as an active ingredient. The Cynanchum wilfordii extract is prepared by washing, drying, and pulverizing Cynanchum wilfordii and isolating Cynanchum wilfordii using 70-90% ethanol at 90-98°C for 5-7 hours.
Abstract:
본 발명은 청호 추출물을 유효성분으로 포함하는 기억력 및 학습 능력 증진용 조성물 및 인지기능장애 예방 및 치료용 조성물에 관한 것이다. 본 발명은 아세틸콜린스테라아제의 활성을 억제, 항산화 활성(예컨대, 활성산소종) 및 NMDA 리셉터와의 친화력을 통하여 신경세포, 특히 대뇌 기저부의 신경세포의 손상을 억제시킬 수 있는 효과를 가진다. 본 발명은 신경세포를 보호 및 손상의 예방 효과를 통하여 기억력 및 학습 능력을 증진시킬 수 있을 뿐 만 아니라 인지기능장애로 질환을 예방 및 치료 할 수 있는 효능을 발휘한다. 또한, 본 발명은 기억력 및 학습 능력의 증진 효능, 또는 인지기능장애를 예방 및 치료 효능을 가지는 청호 추출물의 의약 및 식품으로서의 기초적인 자료를 제공한다.