Abstract:
본 발명은 시아니딘-3 배당체(cyanidin-3-glycoside)또는 이를 포함하는 흑미 추출물을 함유하는 고지혈증의 예방 및 치료용 조성물에 관한 것이다. 보다 구체적으로, 본 발명은 시아니딘-3 배당체 또는 이를 포함하는 흑미 추출물을 함유하는 고지혈증 예방 및 치료용 기능성 식품 조성물 및 약학 조성물에 관한 것이다. 본 발명에 따른 시아니딘-3 배당체 또는 흑미 추출물을 유효성분으로 하는 조성물은 생체 내 콜레스테롤 및 중성지방 함량을 감소시키고 생체 내 지방의 흡수를 억제함으로써 고지혈증을 예방 또는 치료하는 효과가 있다. 시아니딘-3 배당체, 흑미 추출물, 고지혈증
Abstract:
PURPOSE: A food composition for preventing and treating hyperlipidemia containing cyanidin-3-glucoside and black rice containing cyanidin-3-glucoside as a main ingredient is provided. It has an effect of preventing and treating hyperlipidemia by reducing the content of cholesterol and neutral lipid and inhibiting fat absorption in the body. CONSTITUTION: The food composition for preventing and treating hyperlipidemia contains 2 to 20% by weight of cyanidin-3-glucoside represented by the formula 1, black rice containing cyanidin-3-glucoside and additionally vitamin C, taurine and carnitine, based on the total weight of the composition. The food is in the shape of a beverage. The cyanidin-3-glucoside can be prepared by the steps of: adding an organic acid solvent containing an acid to black rice powder obtained by grinding black rice or black rice bran obtained by polishing black rice; separating crude pigments therefrom; and subjecting to cation-exchange chromatography. The acid is acetic acid, phosphoric acid, hydrochloric acid, citric acid and malic acid, the organic solvent is methanol, ethanol etc.