公开(公告)号：KR1020090078939A

公开(公告)日：2009-07-21

申请号：KR1020080004805

申请日：2008-01-16

Applicant: 한국화학연구원 ,  한국식품연구원

Inventor： 김영섭 ,  유시용 ,  연규환 ,  홍경식 ,  이병회 ,  유미영 ,  최연희 ,  김현기 ,  박우규 ,  고우석 ,  권대영 ,  하태열

IPC: A61K31/192 ,  A61K31/045 ,  A61K31/343 ,  A61P25/28

Abstract: A composition for preventing and treating neutodegenerative disease, which contains a polyphenol compound as an active ingredient is provided to have the effects of beta-amyloid coagulation inhibition, caspase-3 activity suppression and acetylcholinesterase activation suppression. A composition for preventing and treating neurodegenerative diseases comprises salvianolic acid, bakuchiol, epsilon-viniferin, rhapontigenin, piceatannol, luteolin, myricetin, or their mixture as an active ingredient. The neurodegenerative diseases are Alzheimer's disease, Pick's disease, Creutzfeldt-jakob, Parkinson's disease, Lou Gehrig's Disease, or Huntington's disease. The composition suppresses BACE-1[beta-site APP(amyloid precursor protein)-cleaving enzyme 1], caspase or acetylcholine esterase. The composition further comprises medicinal herb. The medicinal herb is Salviae Miltiorrhizae Radix, Psoraleae Semen, Vitidis Fructus, Rhei Rhizoma, Digitalis Folium, Schizonepeta Herba, Taraxaci Herba, Humuli Herba, Lonicerae Folium or their mixture.

Abstract translation: 提供含有多酚化合物作为活性成分的用于预防和治疗神经变性疾病的组合物，以具有β-淀粉样蛋白凝结抑制，半胱天冬酶-3活性抑制和乙酰胆碱酯酶活化抑制的作用。 用于预防和治疗神经变性疾病的组合物包括salvianolic acid，bakuchiol，ε-viniferin，rhapontigenin，piceatannol，木犀草素，杨梅宁或其混合物作为活性成分。 神经变性疾病是阿尔茨海默氏病，皮克病，克雅氏综合征，帕金森氏病，卢格里希氏病或亨廷顿舞蹈病。 该组合物抑制BACE-1β-位点APP（淀粉样蛋白前体蛋白）切割酶1]，半胱天冬酶或乙酰胆碱酯酶。 该组合物还包含药草。 药用草药是丹参，枸杞子，枸杞子，枸杞子，洋地黄属，荆芥草，竹aci草，虎嘴草，金银花或其混合物。

公开(公告)号：KR100833654B1

公开(公告)日：2008-05-29

申请号：KR1020070013661

申请日：2007-02-09

Applicant: 한국화학연구원 ,  한국식품연구원

Inventor： 김영섭 ,  유시용 ,  연규환 ,  홍경식 ,  민용기 ,  김성환 ,  이병회 ,  최연희 ,  김현기 ,  권대영 ,  고우석

IPC: A61K36/78 ,  A61P19/10 ,  A61K31/341

CPC classification number: A61K36/78

Abstract: A composition comprising the extract of Saururus chinensis or active compounds isolated therefrom is provided to inhibit growth of osteoclast, so that the composition is useful for preventing or treating osteoporosis. A composition for preventing or treating osteoporosis comprises 0.01-30 wt.% of the extract of Saururus chinensis, which is prepared by extracting Saururus chinensis with C1-4 alcohol and its solution, dichloromethane, ethylacetate or a mixture thereof, or active compounds isolated from the Saururus chinensis extract including (-)-saucerneol represented by the formula(1) and sauristolactam represented by the formula(2), and is a pharmaceutical or health food composition having a formulation of beverage.

Abstract translation: 提供了包含中华黄牛提取物或从其分离的活性化合物的组合物以抑制破骨细胞的生长，使得该组合物可用于预防或治疗骨质疏松症。 用于预防或治疗骨质疏松症的组合物包括通过用C 1-4醇提取中华黄芪和其溶液，二氯甲烷，乙酸乙酯或其混合物或从其中分离的活性化合物制备的中华黄瓜提取物的0.01-30重量％ 含有由式（1）表示的（ - ） - 三氯蔗糖和由式（2）表示的沙拉耳内酰胺，是具有饮料配方的药物或保健食品组合物。

公开(公告)号：KR1020030097288A

公开(公告)日：2003-12-31

申请号：KR1020020034595

申请日：2002-06-20

Applicant: 한국화학연구원 ,  (주)유니온카본 ,  코리아에프티 주식회사

Inventor： 진항교 ,  정순용 ,  박병기 ,  최정일 ,  이정민 ,  김현기 ,  오재규

IPC: C01B31/08

CPC classification number: C01B32/318 ,  C01B32/342 ,  C01P2006/12

Abstract: PURPOSE: A preparation method of lignocellulose based activated carbon is provided to prepare activated carbon having high density and high performance by a simpler preparation process compared to an existing preparation process. CONSTITUTION: The preparation method comprises processes of mixing lignocellulose, chemical activating agent and water; thermosetting the mixture; pulverizing the thermosetted mixture; adding molding supporting agent to the pulverized material; cohering the molding supporting agent added material; forming the cohered material into a high density pellet shaped thermosetting powder using an injector, and chamfering cohered material at the same time; drying the chamfered thermosetting powder at a temperature of 120 to 150 deg.C for 1 to 2 hours; activating the dried material to a temperature of 400 to 600 deg.C in a furnace; cleaning the residual chemical activating agent using water; and drying the water cleaned residual chemical activating agent, wherein mixing, thermosetting, pulverizing, molding supporting agent adding and cohering processes of the lignocellulose, chemical activating agent and water are performed in a lump in a high shearing force mixer to which a heating source is attached.

Abstract translation: 目的：提供一种木质纤维素基活性炭的制备方法，与现有的制备方法相比，通过更简单的制备方法制备具有高密度和高性能的活性炭。 构成：制备方法包括木质纤维素，化学活化剂和水的混合过程; 热固混合物; 粉碎热固性混合物; 向粉碎材料中加入成型载体; 粘合成型助剂添加材料; 使用注射器将粘结材料形成高密度颗粒状热固性粉末，同时倒角粘结材料; 在120〜150℃的温度下干燥倒角热固性粉末1〜2小时; 在炉中将干燥的材料活化至400至600℃的温度; 用水清洗残留的化学活化剂; 并干燥水清洗残留的化学活化剂，其中木质纤维素，化学活化剂和水的混合，热固化，粉碎，模塑支持剂添加和共聚工艺在高剪切力混合器中进行，加热源为 连接。

公开(公告)号：KR100475512B1

公开(公告)日：2005-03-10

申请号：KR1020020034595

申请日：2002-06-20

Applicant: 한국화학연구원 ,  (주)유니온카본 ,  코리아에프티 주식회사

Inventor： 진항교 ,  정순용 ,  박병기 ,  최정일 ,  이정민 ,  김현기 ,  오재규

IPC: C01B31/08

Abstract: 본 발명은 리그노셀룰로오즈계 성형활성탄 제조방법에 관한 것으로서, 기존 제조공정보다 단순한 공정으로 고밀도, 고성능 성형활성탄을 제조하는데 목적이 있다.
이를 위하여, 공정의 단순화 및 설비의 간소화를 도모할 수 있고, 특히 활성탄의 기계적 강도 및 흡착능을 향상시킬 수 있으며, 에너지절약 및 환경오염감소에 적극적으로 대처할 수 있도록 한 혼합, 열경화, 분쇄, 성형조제첨가, 응집 공정을 일괄적으로 수행할 수 있는 고전단력믹서를 포함하는 리그노셀룰로오즈계 성형활성탄 제조방법을 제공한다.