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公开(公告)号：WO2012150747A1
公开(公告)日：2012-11-08
申请号：PCT/KR2011/008482
申请日：2011-11-08
IPC: C07C319/28 , C07C323/65 , A61K31/10 , A61K36/8962
CPC classification number: C07C319/28 , A23L33/105 , A23L33/115 , A23P10/30 , A61K31/105 , A61K35/20 , A61K36/8962 , A61K2236/00 , C07C323/65
Abstract: 본 발명은 마늘 분쇄물, 마늘 착즙액, 마늘 건조 분말 및 마늘 추출물 중에서 선택되는 어느 하나 이상의 알리신(allicin) 함유 마늘 재료를 준비하는 단계; 상기 알리신 함유 마늘 재료를 유지방과 혼합하는 단계; 및 상기 알리신 함유 마늘 재료와 유지방의 혼합물을 가열하여 반응시키는 단계;를 포함하는 유지방을 이용한 아조엔 강화 유지의 제조방법 및 아조엔 함유 버터의 제조방법에 관한 것으로, 본 발명의 방법을 통해 종래 식물성 유지를 사용하는 방법에 비해 2 배 이상 높은 함량으로 아조엔을 생성시킬 수 있으며, 유지방을 원료로 하므로 기능성 버터를 제조할 수 있도록 한다.
Abstract translation: 本发明涉及一种使用乳脂肪制造辛烯增强脂肪和油的方法以及含有阿约烯的黄油的制造方法，其特征在于，包括以下步骤：制备选自大蒜研磨剂，大蒜提取液，大蒜干燥的含大蒜素的大蒜成分 粉，蒜提取物; 并将含大蒜素的大蒜成分与乳脂混合; 通过加热大蒜素大蒜成分和乳脂肪的混合物反应，本发明能够使用植物油和脂肪使用常规方法产生两倍或更多倍的含量，并且能够通过使用 乳脂为原料。
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公开(公告)号：WO2020242265A1
公开(公告)日：2020-12-03
申请号：PCT/KR2020/007049
申请日：2020-05-29
Abstract: 본 발명은 식품 내 알룰로스의 분석방법 및 이를 이용한 알룰로스 함유 식품의 품질관리 방법에 관한 것으로서, 더욱 자세하게는 식품 내에서 알룰로스를 높은 회수율로 추출할 수 있는 조건을 확립하기 위한 방법을 제공하는 것이다.
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3.发明授权ＢＡＣＥ-1의 활성을 저해하는 파고지 종자 추출물 또는이로부터 분리된 활성물질을 포함하는 퇴행성 뇌질환의예방 또는 치료용 조성물 有权用于预防或治疗包含来自一种PSORALEA CORYLIFOLIA的一种提取物的神经变性疾病的组合物抑制BACE-1或其活性成分的活性
公开(公告)号：KR100833652B1
公开(公告)日：2008-05-29
申请号：KR1020060136696
申请日：2006-12-28
IPC: C07D407/04
Abstract: A composition comprising the extract of Psoralea corylifolia seed or effective compounds contained therein is provided to inhibit the activity of BACE-1(beta-site APP(amyloid precursor protein)-cleaving enzyme 1) mediating the formation of beta-amyloid as a main causing material of dementia, so that the composition is useful for preventing or treating neurodegenerative disease. A composition for preventing or treating neurodegenerative disease comprises the extract of Psoralea corylifolia seed, which is prepared by extracting Psoralea corylifolia seeds with C1-4 alcohol or its solution, dichloromethane, ethylacetate or a mixture thereof, or a compound selected from 7-hydroxy-3-(4-methyl-4-(4-methylpentene-3-yl)-4H-chromen-6-yl)-4H-chromen-4-one represented by the formula(1), bakuchiol, bavachromene, isobavachromene, bavachalcone, isobavachalcone, bavachinin, 7,8-dihydro-8-(4-hydrophenyl)-2,2-dimethyl-2H,6H-[1,2-b:5,4-b']dipyran-6-one isolated from the extract of Psoralea corylifolia seed.
Abstract translation: 提供包含补骨脂素提取物或其中含有的有效化合物的组合物以抑制BACE-1（β-位点APP（淀粉样蛋白前体蛋白）切割酶1）的活性，其介导β-淀粉样蛋白的形成作为主要原因 因此该组合物可用于预防或治疗神经退行性疾病。 用于预防或治疗神经退行性疾病的组合物包括通过用C 1-4醇或其溶液，二氯甲烷，乙酸乙酯或其混合物或选自7-羟基-2-甲基苯酚的化合物提取茄科植物提取物的方法制备的补骨脂素提取物， 由式（1）表示的3-（4-甲基-4-（4-甲基戊烯-3-基）-4H-色烯-6-基）-4H-色烯-4-酮，苯甲酸，巴伐溴苯，异葎草酮，巴伐昔酮 ，异哈查酮，巴伐他丁，7,8-二氢-8-（4-氢苯基）-2,2-二甲基-2H，6H- [1,2-b：5,4-b']二吡喃-6-酮 茯苓提取物。
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公开(公告)号：KR1020070068689A
公开(公告)日：2007-07-02
申请号：KR1020050130601
申请日：2005-12-27
Abstract: A composition for immunosuppression comprising the extract of Saururus chinensis or active compounds isolated therefrom is provided to inhibit abnormal proliferation of B cell and T cell, so that the composition is useful for prevention and treatment of diseases caused by hypersensitive immune responses. The composition for immunosuppression comprises the extract of Saururus chinensis or an active compound isolated from the Saururus chinensis extract selected from (-)-saucerneol, saucerneol C, manassantin A, manassantin B and a mixture thereof as effective ingredient, wherein the Saururus chinensis extract is prepared by using an organic solvent selected from methanol, methanol solution, ethanol, ethanol solution, butanol, dichloromethane, ethylacetate and a mixture thereof. The composition is a pharmaceutical or health food composition. The pharmaceutical composition prevents or treats diseases caused by hypersensitive immune responses including organ transplant rejection, autoimmune disease including lupous erythematosus and rheumatoid arthritis, and allergy disease including rhinitis, asthma and atopic dermatitis, and the health food composition is formulated as drink.
Abstract translation: 提供了包含中华黄牛提取物或从其分离的活性化合物的免疫抑制组合物以抑制B细胞和T细胞的异常增殖，使得该组合物可用于预防和治疗由过敏免疫应答引起的疾病。 用于免疫抑制的组合物包含中华黄牛提取物或从中选出的（ - ） - 沙美拉诺，沙门氏菌素C，马那敏蛋白A，他曼那丁B及其混合物中选择的中华黄瓜提取物作为有效成分分离的活性化合物，其中中华黄瓜提取物为 通过使用选自甲醇，甲醇溶液，乙醇，乙醇溶液，丁醇，二氯甲烷，乙酸乙酯及其混合物的有机溶剂制备。 该组合物是药物或保健食品组合物。 药物组合物预防或治疗由过敏免疫应答引起的疾病，包括器官移植排斥反应，自身免疫性疾病，包括红斑狼疮和类风湿性关节炎，以及过敏疾病，包括鼻炎，哮喘和特应性皮炎，健康食品组合物配制成饮料。
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公开(公告)号：KR100749675B1
公开(公告)日：2007-08-17
申请号：KR1020050130601
申请日：2005-12-27
Abstract: 본 발명은 삼백초(
Saururus chinensis ) 추출물, 또는 이로부터 분리된 (-)-소서네올[(-)-saucerneol], 소서네올 C(saucerneol C), 마나산틴 A(manassantin A) 또는 마나산틴 B를 유효성분으로 함유하는 면역억제용 조성물에 관한 것이다. 본 발명에 따른 조성물은 비정상적인 B 세포 및 T 세포의 증식을 효과적으로 억제하여 우수한 면역억제효과를 나타내므로 장기이식거부반응, 자가면역질환, 알러지, 아토피 등과 같은 면역과민반응으로 야기되는 질환의 예방 및 치료를 위한 약학 조성물뿐만 아니라 식품첨가물로도 유용하게 사용될 수 있다.-
Patent Agency Ranking
公开(公告)号：KR1020090078939A
公开(公告)日：2009-07-21
申请号：KR1020080004805
申请日：2008-01-16
IPC: A61K31/192 , A61K31/045 , A61K31/343 , A61P25/28
Abstract: A composition for preventing and treating neutodegenerative disease, which contains a polyphenol compound as an active ingredient is provided to have the effects of beta-amyloid coagulation inhibition, caspase-3 activity suppression and acetylcholinesterase activation suppression. A composition for preventing and treating neurodegenerative diseases comprises salvianolic acid, bakuchiol, epsilon-viniferin, rhapontigenin, piceatannol, luteolin, myricetin, or their mixture as an active ingredient. The neurodegenerative diseases are Alzheimer's disease, Pick's disease, Creutzfeldt-jakob, Parkinson's disease, Lou Gehrig's Disease, or Huntington's disease. The composition suppresses BACE-1[beta-site APP(amyloid precursor protein)-cleaving enzyme 1], caspase or acetylcholine esterase. The composition further comprises medicinal herb. The medicinal herb is Salviae Miltiorrhizae Radix, Psoraleae Semen, Vitidis Fructus, Rhei Rhizoma, Digitalis Folium, Schizonepeta Herba, Taraxaci Herba, Humuli Herba, Lonicerae Folium or their mixture.
Abstract translation: 提供含有多酚化合物作为活性成分的用于预防和治疗神经变性疾病的组合物，以具有β-淀粉样蛋白凝结抑制，半胱天冬酶-3活性抑制和乙酰胆碱酯酶活化抑制的作用。 用于预防和治疗神经变性疾病的组合物包括salvianolic acid，bakuchiol，ε-viniferin，rhapontigenin，piceatannol，木犀草素，杨梅宁或其混合物作为活性成分。 神经变性疾病是阿尔茨海默氏病，皮克病，克雅氏综合征，帕金森氏病，卢格里希氏病或亨廷顿舞蹈病。 该组合物抑制BACE-1β-位点APP（淀粉样蛋白前体蛋白）切割酶1]，半胱天冬酶或乙酰胆碱酯酶。 该组合物还包含药草。 药用草药是丹参，枸杞子，枸杞子，枸杞子，洋地黄属，荆芥草，竹aci草，虎嘴草，金银花或其混合物。
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公开(公告)号：KR100878331B1
公开(公告)日：2009-01-14
申请号：KR1020070082438
申请日：2007-08-16
IPC: A61K31/343 , A61K36/87 , A61P3/04
Abstract: An anti-obesity pharmaceutical composition, and the anti-obesity food are provided to inhibit the differentiation of preadipocyte into adipocyte and to suppress the synthesis of cholesterol. An anti-obesity pharmaceutical composition comprises the extract of grape tree bark, or at least one component selected from the vitisin A represented by the formula 1, the vitisin B represented by the formula 2, the epsilon-viniferin represented by the formula 3 and the ampelopsin represented by the formula 4 which are separated from the extract of grape tree bark.
Abstract translation: 提供抗肥胖药物组合物和抗肥胖食品，以抑制前脂肪细胞分化成脂肪细胞并抑制胆固醇的合成。 抗肥胖药物组合物包含葡萄树皮提取物或选自由式1表示的维生素A，由式2表示的维生素B，由式3表示的ε-荧光素和 由葡萄树皮提取物分离的由式4表示的黄曲霉素。
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公开(公告)号：KR101631315B1
公开(公告)日：2016-06-20
申请号：KR1020140044368
申请日：2014-04-14
Applicant: 한국식품연구원
Abstract: 본발명은 (a) 마늘분쇄체의현탁액또는마늘추출물에효모를접종시키는단계; 및 (b) 상기단계 (a)의효모접종결과물을배양하여마늘의유기황화합물을생물전환(biotransformation)시킴으로써 SAC[(+)-S-allyl-1-cystein)], SPC(S-trans-1-propenyl-L-cysteine) 및 SMC(S-methyl-cysteine)로구성된군으로부터선택되는하나이상의유기황화합물을인리치먼트(enrichment)시키는단계를포함하는마늘의유기황화합물(organosulfur compounds)의생물전환방법에관한것이다. 본발명은마늘내 유효한유기황화합물을생물전환시켜유기황화합물의효율을개선할수 있다.
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公开(公告)号：KR1020120124037A
公开(公告)日：2012-11-12
申请号：KR1020120044931
申请日：2012-04-27
Applicant: 한국식품연구원
IPC: A23C15/14 , A23L27/10 , A23L33/00 , C07C319/28
CPC classification number: C07C319/28 , A23L33/105 , A23L33/115 , A23P10/30 , A61K31/105 , A61K35/20 , A61K36/8962 , A61K2236/00 , C07C323/65
Abstract: PURPOSE: A producing method of butter containing ajoene using milk fan containing the ajoene is provided to enable users to mass-produce the butter containing the ajoene. CONSTITUTION: A producing method of butter containing ajoene comprises the following steps: preparing a garlic material containing allicin selected from garlic puree, garlic juice, dried garlic powder, or a garlic extract; mixing the garlic material with milk fat; heating the mixture to obtain the milk fat containing the ajoene; cooling the heated mixture, and fermenting or aging the mixture; churning, or centrifugal-separating the mixture to obtain butter particles; and adding salt or food dye into the butter particles, and working the butter particles. [Reference numerals] (AA) Peeling garlic gloves; (BB) Crushing; (CC) Juicing; (DD) Garlic juice; (EE) Garlic juice residue; (FF) Mixing milk fat; (GG) Homogenizing; (HH) Ultrasonic processing; (II) Ajoene producing reaction; (JJ) Cooling; (KK) Fermenting and aging; (LL) Churning; (MM) Butter particle; (NN) Washing; (OO) Salting and adding pigments; (PP) Working; (QQ) Filling and packaging; (RR) Butter; (RR) Second step; (SS) First step; (UU) Third step
Abstract translation: 目的：提供使用含有香草的奶粉的含有丁香的黄油的生产方法，以使用户能够大量生产含有香草的黄油。 构成：含有多烯的黄油的生产方法包括以下步骤：制备选自大蒜泥，蒜汁，干蒜粉或大蒜提取物中的大蒜素的大蒜物质; 将大蒜料与乳脂混合; 加热该混合物以获得含有阿约烯的乳脂; 冷却加热的混合物，发酵或老化混合物; 搅拌或离心分离混合物以获得黄油颗粒; 并向黄油颗粒中加入盐或食用染料，并加工黄油颗粒。 （附图标记）（AA）剥皮大蒜手套; （BB）粉碎; （CC）榨汁; （DD）蒜汁; （EE）蒜汁残渣; （FF）混合乳脂; （GG）均质; （HH）超声波处理; （二）生产乙烯的反应; （JJ）冷却; （KK）发酵和老化; （LL）搅拌; （MM）黄油颗粒; （NN）洗涤; （OO）盐析和添加颜料; （PP）工作; （QQ）灌装包装; （RR）黄油; （RR）第二步; （SS）第一步; （UU）第三步
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公开(公告)号：KR101672007B1
公开(公告)日：2016-11-03
申请号：KR1020140122126
申请日：2014-09-15
Applicant: 한국식품연구원
IPC: A61K36/8962 , A61P3/10 , A61P3/00
Abstract: 본발명은모나스커스필로서스()를이용한마늘발효물을포함하는조성물에관한것으로, 마늘분쇄체의현탁액또는마늘추출물에모나스커스필로서스를접종하여발효시킨마늘발효물을유효성분으로포함하는인슐린저항성또는인슐린저항성관련질환의예방또는치료용약제학적조성물및 예방또는개선용기능성식품조성물을제공한다. 본발명의조성물은당수용체발현증진효과, 당흡수향상효과, 혈당조절효과및 체중조절효과를갖는다.
Abstract translation: 本发明涉及包含使用红曲霉的大蒜发酵产品，更具体地涉及用于预防或治疗胰岛素抵抗和胰岛素抵抗相关疾病的药物组合物的组合物，以及用于预防或减轻胰岛素抵抗的功能性食品组合物， 胰岛素抵抗相关疾病 药物组合物和功能性食品组合物通过将红曲霉接种到大蒜粉碎体或大蒜提取物的悬浮液中，作为活性成分包含大蒜发酵产物，然后发酵。 此外，本发明的组合物具有促进糖受体表达，改善糖吸收，控制血糖和控制重量的作用。
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