公开(公告)号：KR100866836B1

公开(公告)日：2008-11-04

申请号：KR1020070046013

申请日：2007-05-11

Applicant: 한양대학교 산학협력단

Inventor： 안유민 ,  고용준 ,  강도형 ,  황승용 ,  이병철 ,  하승모

IPC: C12Q1/68 ,  C12Q1/00

CPC classification number: B01L3/5027 ,  C12Q1/6862

Abstract: A micro bio-chip for the ligation reaction is provided to perform a mixing process having high efficiency in a structure of a single layer by combination-arranging in a form of a micro-pillar and a micro-nozzle at the micromixer part, to manufacture it easily because a micromixer does not use an actuator, to diminish an installation cost and to generate stabilized biochemical reaction. A micro bio-chip for the ligation reaction is made of 2 layer of structure by integrating polydimethylsiloxane(PDMS) chip and glass(20). The PDMS chip(10) comprises an inlet part, a micro-mixer, a reactor and an outlet part. The micro-mixer mixes a sample injected through the inlet part(11). A reactor ligation-reacts the mixed sample through the micromixer(12). The micromixer comprises a micro pillar and a micro-nozzle.

Abstract translation: 提供了一种用于连接反应的微生物芯片，通过在微型混合器部分上以微柱和微型喷嘴的形式组合配置，进行单层结构的高效率的混合过程，以制造 这很容易，因为微混合器不使用致动器，以减少安装成本并产生稳定的生化反应。 用于连接反应的微生物芯片由聚二甲基硅氧烷（PDMS）芯片和玻璃（20）组成，由2层结构构成。 PDMS芯片（10）包括入口部分，微混合器，反应器和出口部分。 微混合器混合通过入口部分（11）注入的样品。 反应器连接 - 通过微混合器（12）将混合样品反应。 微混合器包括微柱和微喷嘴。