Abstract:
The disclosed tamper-evident closure (100) encloses a medical access device (200), such as a vascular access device and includes an actuatable door (127) to create an optional access point (113) for accommodating various arrangements of medical access devices within the tamper-evident closure. The tamper-evident closure comprises a holding cavity (110), an access point into the holding cavity, an actuatable door covering the access point, and a hinge (127c) connecting the actuatable door to the holding cavity.
Abstract:
A sample collection device includes a housing including an exhalation portion and a coupling portion. The coupling portion can be coupled with/to a sample collection tube. An airflow path extends through the housing. The device further includes porous sample collection media partially disposed between within the housing and arranged to occlude the airflow path. The porous sample collection includes nonwoven material and may include polylactic acid, polypropylene, or a combination thereof. The housing can be a single piece, part, or component, or can be multiple pieces, parts, components, or portions. In an embodiment of a two-piece housing, the first part includes an exhalation piece (e.g., a mouthpiece or nosepiece) and the second part includes a coupling end constructed for coupling with a sample collection tube. A method of obtaining a sample using the sample collection device includes breathing into the exhalation piece or portion to collect a sample on the porous sample collection media; coupling the second part or portion with a sample collection tube; and transferring the collected sample on the porous sample collection media into the sample collection tube.
Abstract:
A sample collection system includes a housing comprising a first part and a second part, the first and second parts being movable relative to one another; porous sample collection media disposed along an airflow path in the first part; and an assay disposed on the second part and constructed to receive a sample captured by the porous sample collection media. The first and second parts are rotatably movable relative to one another. Moving the first and second parts relative to one another aligns the porous sample collection media with at least a portion of the assay. The assay may be a lateral flow assay or a vertical flow assay. The media is constructed to collect a sample from exhalation airflow. A collected sample may be eluted from the media onto the assay using a liquid.
Abstract:
A sample collection device including a housing extending from a mouthpiece portion to an air outlet portion. The housing defines an airflow channel from the mouthpiece portion to the air outlet portion. The mouthpiece portion is configured to receive an exhalation airflow. A porous sample collection media is disposed within the housing and along the airflow channel. A fluid inlet port defines an aperture through the housing and is adjacent to the porous sample collection media. The fluid inlet port is configured to direct fluid onto the porous sample collection media. A metered fluid dose element is attached to the fluid inlet port. The metered fluid dose element is configured to dispense a metered volume of fluid into the fluid inlet port.
Abstract:
A disinfecting device for a Luer-activated device having a septum is disclosed. The disinfecting device includes a cap, a plunger including a standoff and a face, and a disinfectant. When the Luer-activated device is secured to the disinfecting device, the Luer-activated devices engaged with the standoff but Luer-activated device septum does not contact the standoff or the face.
Abstract:
An applicator (100) including a hollow body (110), the hollow body including a distal portion (112), a proximal portion (114), an exterior surface (118), an interior surface (116), and an activation region (120), where the hollow body includes at least two longitudinal grooves (122) on at least one of the exterior surface and the interior surface in the activation region of the applicator, and where the hollow body has a first radial groove (124) in the activation region that is on at least one of the exterior surface or the interior surface. The applicator includes a frangible ampoule (160) inside the hollow body, the frangible ampoule configured to contain a solution. The applicator may include a head (140) having an absorbent component (150) capable of absorbing the contents of the frangible ampoule when the ampoule is fractured and can aid in application of the ampoule contents to the desired surface.
Abstract:
Method of using a shape-formable apparatus comprising fibrous material. A shape-formable apparatus can include an envelope defining a chamber, a port positioned to fluidly couple the chamber with ambience, and a fibrous material positioned in the chamber. The fibrous material can be substantially less formable when the apparatus is in the second state than when the apparatus is in the first state. The method can include providing the shape-formable apparatus in a first state; forming the apparatus into a desired shape; and reducing the pressure in the chamber to change the apparatus from the first state to a second state in which the apparatus is substantially less formable than in the first state.
Abstract:
A protected sample collection media for use in a sample collection device includes a piece of porous sample collection media having a first major side and an opposing second major side; and a protective sheath fully covering the first major side and the second major side. The protective sheath has a first portion and a second portion. The first portion is removable without removing the second portion. The second portion forms a tab constructed to be gripped by hand. The protected sample collection media may be part of a system including a sample collection device. The system may be provided as a kit including instructions for use of the kit.
Abstract:
The present disclosure relates to sample collection devices and sample collection and testing devices. The devices described herein includes a housing defining a fluid channel from a first portion to a second portion. The devices further include a porous sample collection media disposed within the housing and in fluid communication with the fluid channel. The devices further include a fluid inlet port disposed in fluid communication with the porous sample collection media. The fluid inlet port is configured to direct a test fluid onto the porous sample collection media. The sample collection device further includes an assay configured to receive a fluid that was incident on the porous sample collection media (and eluent) and test that eluent for the presence (or absence) of a pathogen or virus.
Abstract:
A disinfecting device for a Luer-activated device having a septum is disclosed. The disinfecting device includes a cap, a plunger including a standoff and a face, and a disinfectant. When the Luer-activated device is secured to the disinfecting device, the Luer-activated devices engaged with the standoff but Luer-activated device septum does not contact the standoff or the face.