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公开(公告)号：WO2012088064A1
公开(公告)日：2012-06-28
申请号：PCT/US2011/066079
申请日：2011-12-20
Applicant: 3M INNOVATIVE PROPERTIES COMPANY , FOLTZ, William E. , AHIMOU, Francois , BOMMARITO, G. Marco , ASMUS, Robert A. , HADDAD, Louis C. , KSHIRSAGAR, Tushar A.
Inventor： FOLTZ, William E. , AHIMOU, Francois , BOMMARITO, G. Marco , ASMUS, Robert A. , HADDAD, Louis C. , KSHIRSAGAR, Tushar A.
CPC classification number: C12Q1/22 , C12Q1/25 , G01N21/78 , G01N31/226 , G01N33/573 , G01N2021/7786 , G01N2458/00
Abstract: Sterilization indicators that include a neutralizer, such indicators useful for testing the effectiveness of a sterilization procedure by measuring the activity of an active enzyme whose activity is correlated with the survival of microorganisms.
Abstract translation: 包括中和剂的消毒指示剂，这些指标可用于通过测量活性与微生物存活相关的活性酶的活性来测试灭菌程序的有效性。
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2.发明申请FIBRIN COMPOSITION COMPRISING CARRIER MATERIAL, METHOD AND WOUND ARTICLES 审中-公开包含载体材料的纤维蛋白组合物，方法和伤口制品
公开(公告)号：WO2018067628A1
公开(公告)日：2018-04-12
申请号：PCT/US2017/055022
申请日：2017-10-04
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： BJORK, Jason W. , DETERMAN, Amy S. , O'HARE, Jonathan J. , ASMUS, Robert A. , DIZIO, James P. , TIAN, Zhicheng
Abstract: Provided is a method of forming a fibrin hydrogel composition, the method including providing a fibrin hydrogel or precursor thereof, comprising fibrin hydrogel forming salt. The fibrin hydrogel forming salt concentration is greater than or equal to the threshold concentration to form a fibrin hydrogel. The method further includes combining the fibrin hydrogel with a carrier material. The concentration of the carrier material typically ranges from 0.1 to about 50 wt.-%. The method further includes reducing the salt concentration below the threshold concentration to form a fibrin hydrogel.
Abstract translation: 提供形成纤维蛋白水凝胶组合物的方法，所述方法包括提供包含纤维蛋白水凝胶形成盐的纤维蛋白水凝胶或其前体。 形成纤维蛋白水凝胶的盐浓度大于或等于形成纤维蛋白水凝胶的阈值浓度。 该方法进一步包括将纤维蛋白水凝胶与载体材料组合。 载体材料的浓度通常在0.1至约50重量％的范围内。 该方法还包括将盐浓度降低到阈值浓度以下以形成血纤蛋白水凝胶。
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公开(公告)号：WO2018067622A1
公开(公告)日：2018-04-12
申请号：PCT/US2017/055015
申请日：2017-10-04
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： DIZIO, James P. , TIAN, Zhicheng , BJORK, Jason W. , DETERMAN, Amy S. , ASMUS, Robert A. , O'HARE, Jonathan J.
Abstract: Provided is a method of forming a fibrinogen hydrogel composition, the method including providing a fibrinogen hydrogel or precursor thereof, comprising fibrinogen hydrogel forming salt. The fibrinogen hydrogel forming salt concentration is greater than or equal to the threshold concentration to form a fibrinogen hydrogel. The method further includes denaturing the fibrinogen hydrogel such as by heating. The method optionally further includes combining the fibrinogen hydrogel with a carrier material. When present, the concentration of the carrier material typically ranges from 0.1 to about 50 wt.-%. The method further includes reducing the salt concentration below the threshold concentration to form a fibrinogen hydrogel.
Abstract translation: 提供形成纤维蛋白原水凝胶组合物的方法，所述方法包括提供包含纤维蛋白原水凝胶形成盐的纤维蛋白原水凝胶或其前体。 形成纤维蛋白原水凝胶的盐浓度大于或等于阈值浓度以形成纤维蛋白原水凝胶。 该方法还包括例如通过加热使纤维蛋白原水凝胶变性。 该方法任选地进一步包括将纤维蛋白原水凝胶与载体材料组合。 当存在时，载体材料的浓度通常在0.1至约50重量％的范围内。 该方法还包括将盐浓度降低至低于阈值浓度以形成纤维蛋白原水凝胶。
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公开(公告)号：WO2017112457A1
公开(公告)日：2017-06-29
申请号：PCT/US2016/066333
申请日：2016-12-13
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： RASMUSSEN, Jerald K. , DEMIRGÖZ, Döne , CHRISTIAN, Taylor M. , KIPKE, Cary A. , BEVERIDGE, Nicole Morozowich , KLEIN, Andrew P. , HAYS, David S. , DIZIO, James P. , GRIESGRABER, George W. , ASMUS, Robert A.
IPC: C09J4/06 , C07C69/36 , C09J133/06 , C09J135/00
CPC classification number: C09J4/06 , C09J133/06 , C09J135/00
Abstract: Polymeric materials are disclosed herein that include a reaction product of components comprising: a) a first amine component having at least two and at most three primary amino groups, secondary amino groups, or a mixture thereof, with the proviso that the first amine component is not a silicone diamine; b) a second amine component having (i) greater than three primary amino groups, or (ii) at least three primary amino groups and a plurality of secondary amino groups, wherein the second amine component is a polymeric material having a carbon backbone or a polymeric material having a carbon backbone with a plurality of catenated nitrogen atoms; and c) an oxalate ester.
Abstract translation: 本文公开了聚合物材料，其包括组分的反应产物，所述组分包含：a）具有至少两个且至多三个伯氨基，仲氨基或其混合物的第一胺组分与 条件是第一胺组分不是硅氧烷二胺; b）第二胺组分，其具有（i）大于三个伯氨基，或（ii）至少三个伯氨基和多个仲氨基，其中第二胺组分是具有碳主链或 具有碳主链的多个连接的氮原子的聚合物材料; 和c）草酸酯。
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5.发明申请
公开(公告)号：WO2016164316A1
公开(公告)日：2016-10-13
申请号：PCT/US2016/025910
申请日：2016-04-04
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： LANGER-ANDERSON, Delony L. , GRIESGRABER, George W. , COLAK ATAN, Semra , PEREIRA, Junia , WLASCHIN, Katie F. , YOUNG, Alexi J. , ASMUS, Robert A. , KOHLER RIEDI, Petra L. , HAYS, David S. , RASMUSSEN, Jerald K. , SOLBERG, Michael J.
IPC: C08L31/00
CPC classification number: A61L26/0066 , A61K9/7015 , A61K31/275 , A61K47/34 , A61L24/001 , A61L24/0015 , A61L24/043 , A61L24/06 , A61L26/00 , A61L26/0004 , A61L26/0019 , A61L26/0052 , A61L26/0061 , A61L26/0095 , A61L2300/404 , A61L2300/418 , A61L2400/04 , A61L2430/34 , Y02A50/473 , C08L83/04
Abstract: Film forming gel compositions, useful in creating conformable and flexible gel bandages, can be formulate from a film forming polymer, a tackifier, and a volatile solvent. The film forming gels can also include antiseptics, cationic polymer coagulants, fillers, and other additives. The gel compositions form relatively thick films when dried on tissue, and can exhibit enhanced breathability to promote wound healing.
Abstract translation: 可用于形成适形和柔性凝胶绷带的成膜凝胶组合物可以由成膜聚合物，增粘剂和挥发性溶剂配制。 成膜凝胶也可以包括防腐剂，阳离子聚合物凝结剂，填料和其它添加剂。 凝胶组合物在组织上干燥时形成相对厚的膜，并且可以表现出增强的透气性以促进伤口愈合。
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Patent Agency Ranking
公开(公告)号：WO2020240337A1
公开(公告)日：2020-12-03
申请号：PCT/IB2020/054704
申请日：2020-05-18
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： ZHANG, Ying , ASMUS, Robert A. , TIAN, Zhicheng , VANG, Kheng , DIZIO, James , PARKS, Patrick J. , SPIEWAK, Brian E.
Abstract: Adhesive compositions are disclosed that include an octenidine salt, a resin system, a plasticizer, and a cidatrope. The dried adhesive compositions are substantially free of water and C 2 – C 5 alcohols. The adhesive compositions disclosed are formulations that provide rapid and persistent antimicrobial activity and may be useful, for example, in wound dressings, surgical drapes, and medical tapes.
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7.发明申请
公开(公告)号：WO2016164315A1
公开(公告)日：2016-10-13
申请号：PCT/US2016/025904
申请日：2016-04-04
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： LANGER-ANDERSON, Delony L. , GRIESGRABER, George W. , COLAK ATAN, Semra , PEREIRA, Junia M. , WLASCHIN, Katie F. , YOUNG, Alexi J. , ASMUS, Robert A. , KOHLER RIEDI, Petra L. , HAYS, David S. , RASMUSSEN, Jerald K. , SOLBERG, Michael J.
IPC: A61L24/06 , A61L26/00 , A61K31/275 , A61K9/70
CPC classification number: A61L26/0066 , A61K9/7015 , A61K31/275 , A61K47/34 , A61L24/001 , A61L24/0015 , A61L24/043 , A61L24/06 , A61L26/00 , A61L26/0004 , A61L26/0019 , A61L26/0052 , A61L26/0061 , A61L26/0095 , A61L2300/404 , A61L2300/418 , A61L2400/04 , A61L2430/34 , Y02A50/473 , C08L83/04
Abstract: Film forming gel compositions, useful in creating conformable and flexible gel bandages, can be formulate from a film-forming polymer, a tackifier, and a volatile solvent. The film forming gels can also include antiseptics, cationic polymer coagulants, fillers, and other additives. The gel compositions form relatively thick films when dried on tissue, and can exhibit enhanced breathability to promote wound healing.
Abstract translation: 可以从成膜聚合物，增粘剂和挥发性溶剂配制用于产生适形和柔性凝胶绷带的成膜凝胶组合物。 成膜凝胶也可以包括防腐剂，阳离子聚合物凝结剂，填料和其它添加剂。 凝胶组合物在组织上干燥时形成相对厚的膜，并且可以表现出增强的透气性以促进伤口愈合。
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公开(公告)号：WO2016010742A1
公开(公告)日：2016-01-21
申请号：PCT/US2015/038969
申请日：2015-07-02
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： ASMUS, Robert A. , LEE, Hae-Seung , ZHU, Dong-Wei
IPC: C09D133/16
CPC classification number: C09D133/16 , A61L26/0014 , C08F220/18 , C08F230/08 , C08F2220/1825 , C09D143/04 , C08F220/14 , C08F220/24 , C08F2220/1891
Abstract: Conformable coating composition are described comprising a (meth)acrylate copolymer comprising interpolymerized monomer units of fluorinated monomer and a volatile solvent having a solubility parameter from 4.9-12.5 (cal/cm 3 ) 1/2 . In some embodiments, the fluorinated monomer has a Tg
Abstract translation: 描述了包含包含氟化单体的共聚单体单元和溶解度参数为4.9-12.5（cal / cm 3）1/2的挥发性溶剂的（甲基）丙烯酸酯共聚物的一致性涂料组合物。 在一些实施方案中，氟化单体的Tg <30℃。 在一些实施方案中，干燥的涂层在100％的伸长率下不显示阻塞和不大于75％的失效。 还描述了包含本文所述的涂料组合物的干燥涂料组合物的合适膜，包含基材上的适形膜层的制品和包含氟化单体的共聚单元，硅烷单体的共聚物; 和一种或多种Tg≥50℃的单体。
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9.发明申请
公开(公告)号：WO2015047750A1
公开(公告)日：2015-04-02
申请号：PCT/US2014/055431
申请日：2014-09-12
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： KANG, Myungchan , PALAZZOTTO, Michael C. , GRYSKA, Stefan H. , ASMUS, Robert A. , WONG, Melvin Y.
IPC: A61B10/00 , A61B5/145 , A61B5/1477 , A61B5/00
CPC classification number: G01N33/0047 , A61B5/14546 , A61B5/1477 , A61B5/44 , A61B5/4845 , A61B10/0064 , A61B2010/0083 , G01D11/245 , G01N33/4972
Abstract: A vapor sensor comprises a housing with an inlet opening in fluid communication a sensor element within the housing. Standoff member(s) are positioned to maintain a gap between the inlet opening and a skin site. An operating circuit is in electrical communication with the sensor element and communicatively coupled to and output member. In use, the output member generates a sensory output indicative to an operator regarding concentration of alcoholic vapor in the ambient atmosphere proximate the skin site upon receiving communication from the operating circuit.
Abstract translation: 蒸气传感器包括壳体，其具有使传感器元件在壳体内流体连通的入口开口。 定位构件定位成在入口和皮肤部位之间保持间隙。 操作电路与传感器元件电连通并且通信地耦合到输出构件。 在使用中，输出构件在接收到来自操作电路的通信时产生指示操作者关于靠近皮肤部位的环境气氛中的醇蒸气的浓度的感觉输出。
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公开(公告)号：WO2020039330A1
公开(公告)日：2020-02-27
申请号：PCT/IB2019/056983
申请日：2019-08-19
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： DOMBROWSKI, Alan R. , ASMUS, Robert A.
IPC: A61M35/00
Abstract: An applicator (100) comprising an elongated hollow body (120) comprising a distal portion (123), a proximal portion (124) having an open end, an exterior surface (127), an interior surface (126), and a filter (135). The interior surface of the applicator defines an internal chamber suitable for receiving an ampoule (160) formed of a frangible material located in the internal chamber proximal to the filter. A spacer (185) having a distal end and a proximal end is provided, and a cap (180) having a proximal portion, a distal portion, an exterior surface, and an interior surface is provided that attaches to the open end of the applicator and maintains the ampoule and spacer in their respective desired positions. The applicator comprises a head (140) including an absorbent component (110) that is capable of absorbing the contents of the frangible ampoule and facilitates applying the contents to the desired surface.
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