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    STETHOSCOPE DISINFECTING APPARATUS
    2.
    发明申请
    STETHOSCOPE DISINFECTING APPARATUS 审中-公开
    STETHOSCOPE消毒设备

    公开(公告)号：WO2011060132A2

    公开(公告)日：2011-05-19

    申请号：PCT/US2010/056336

    申请日：2010-11-11

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY ,  DOMROESE, Michael K. ,  KELLER, Joseph P. ,  BLY, J. George ,  CYBULSKI, Eric R. ,  SCHOLZ, Matthew T. ,  HADDAD, Louis C.

    Inventor： DOMROESE, Michael K. ,  KELLER, Joseph P. ,  BLY, J. George ,  CYBULSKI, Eric R. ,  SCHOLZ, Matthew T. ,  HADDAD, Louis C.

    CPC classification number: A61L2/18 ,  A61B90/70 ,  A61L2202/14 ,  A61L2202/24

    Abstract: The disclosure provides apparatus and assemblies for disinfecting a stethoscope chestpiece. In some embodiments, an apparatus includes an applicator that dispenses a disinfecting fluid when contacted with a stethoscope chestpiece and a motion generator to move the applicator relative to the chestpiece. In some embodiments, an apparatus comprises a chestpiece receiver operably coupled to a means for dispensing a fluid disinfectant. In some embodiments, the assembly includes an absorbent material comprising a plurality of contact regions and a disinfecting fluid and a means for replacing one of the plurality of contact regions with another of the plurality of contact regions. Methods of use are also provided.

    Abstract translation: 本公开提供了用于消毒听诊器胸部的装置和组件。 在一些实施例中，一种装置包括施用器，其在与听诊器胸部和运动发生器接触时分配消毒液体以相对于胸部件移动施用器。 在一些实施例中，装置包括可操作地连接到用于分配流体消毒剂的装置的胸部接收器。 在一些实施例中，组件包括包括多个接触区域和消毒液体的吸收材料以及用于用多个接触区域中的另一个替换多个接触区域中的一个的装置。 还提供了使用方法。

    METHODS AND KIT FOR PROTEASE ENZYME ASSAYS
    4.
    发明申请
    METHODS AND KIT FOR PROTEASE ENZYME ASSAYS 审中-公开
    蛋白酶测定方法和工具包

    公开(公告)号：WO2011031573A1

    公开(公告)日：2011-03-17

    申请号：PCT/US2010/047110

    申请日：2010-08-30

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY ,  STOFFEL, Joseph J. ,  HADDAD, Louis C.

    Inventor： STOFFEL, Joseph J. ,  HADDAD, Louis C.

    IPC: C12Q1/37

    CPC classification number: C12Q1/37 ,  G01N2333/96433 ,  G01N2333/96486 ,  G01N2333/96494 ,  G01N2333/966

    Abstract: A method for testing efficacy of a protease enzyme assay, the method comprising providing an enzyme which acts as a surrogate enzyme control for the protease enzyme; combining the surrogate enzyme control with an assay substrate for the protease enzyme; and determining a change in the assay substrate resulting from the surrogate enzyme control acting on the assay substrate; wherein the protease enzyme is selected from the group consisting of metalloproteinases, serine proteases, and cysteine proteases; a method for conducting a protease enzyme assay using the method for testing efficacy; a kit including an enzyme which acts as a surrogate enzyme control for a protease enzyme in testing efficacy of a protease enzyme assay; and a method of releasing the kit are provided.

    Abstract translation: 一种用于测试蛋白酶测定的功效的方法，所述方法包括提供用作蛋白酶的替代酶对照的酶; 将替代酶控制与用于蛋白酶的测定底物组合; 以及确定由作用在测定底物上的替代酶控制产生的测定底物的变化; 其中所述蛋白酶选自金属蛋白酶，丝氨酸蛋白酶和半胱氨酸蛋白酶; 使用测试功效的方法进行蛋白酶测定的方法; 一种试剂盒，其包括在测试蛋白酶测定的功效中用作蛋白酶的替代酶对照的酶; 并提供了释放试剂盒的方法。

    USE OF FLUIORINATED NONIONIC SURFACTANTS FOR REDUCING NONSPECIFIC BINDING OF MOLECULES TO A SURFACE
    8.
    发明申请
    USE OF FLUIORINATED NONIONIC SURFACTANTS FOR REDUCING NONSPECIFIC BINDING OF MOLECULES TO A SURFACE 审中-公开
    用于减少分子非特异性结合到表面的荧光非离子表面活性剂的使用

    公开(公告)号：WO2005066631A1

    公开(公告)日：2005-07-21

    申请号：PCT/US2004/038054

    申请日：2004-11-15

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY

    Inventor： HADDAD, Louis C. ,  SWENSON, Barbara C. ,  BOTHOF, Cathy C. ,  RAGHAVACHARI, Madhusudan

    IPC: G01N33/53

    CPC classification number: G01N33/54393 ,  C12Q1/6832 ,  Y10S435/962

    Abstract: The present invention provides materials, methods, and kits for reducing nonspecific binding of molecules to a surface, particularly in a solid phase material, and more specifically a solid phase material that includes a hydrophobic portion, by contacting the solid phase material with a fluorinated nonionic surfactant comprising two or more fluorinated hydrophobic segments and one or more hydrophilic segments

    Abstract translation: 本发明提供用于减少分子与表面特别是固相材料的非特异性结合的材料，方法和试剂盒，更具体地说，通过使固相材料与氟化非离子表面活性剂接触，包括疏水部分的固相材料 包含两个或多个氟化疏水链段和一个或多个亲水链段的表面活性剂

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