公开(公告)号：WO2014144759A9

公开(公告)日：2014-11-06

申请号：PCT/US2014029301

申请日：2014-03-14

Applicant: ABBOTT LAB

Inventor： DONOHUE JOSEPH P

IPC: G01N21/00

CPC classification number: G01N35/021 ,  G01N35/026 ,  G01N35/04 ,  G01N35/1002 ,  G01N35/1004 ,  G01N2035/0408 ,  G01N2035/0465 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/25 ,  Y10T436/2575

Abstract: A diagnostic analyzer system includes a linear track, at least one pipetting device, and at least one diagnostic module. The linear track includes a pre-treatment lane disposed parallel to at least one processing lane. The linear track moves reaction vessels, containing samples, held by the pre-treatment lane and by the at least one processing lane. The pre-treatment lane pre-treats the samples in the reaction vessels of the pre-treatment lane. The pre-treatment lane is not connected to any diagnostic module for testing the samples in the reaction vessels of the pre-treatment lane. The at least one pipetting device transfers the pre-treated samples from the reaction vessels in the pre-treatment lane to the reaction vessels in the at least one processing lane.

Abstract translation: 诊断分析器系统包括线性轨道，至少一个移液装置和至少一个诊断模块。 线性轨道包括平行于至少一个处理车道设置的预处理车道。 线性轨道移动由预处理车道和至少一个处理车道保持的包含样品的反应容器。 预处理车道预处理前处理车道的反应容器中的样品。 预处理车道未连接到用于测试预处理车道的反应容器中的样品的任何诊断模块。 至少一个移液装置将预处理车道中的预处理样品从预处理车道中的反应容器转移到至少一个加工车道中的反应容器。

公开(公告)号：WO2014144870A3

公开(公告)日：2015-11-26

申请号：PCT/US2014029462

申请日：2014-03-14

Applicant: ABBOTT LAB

Inventor： DONOHUE JOSEPH P

IPC: B01J19/18 ,  C12M1/34 ,  G01N17/02

CPC classification number: G01N35/021 ,  G01N21/76 ,  G01N35/0099 ,  G01N35/02 ,  G01N35/04 ,  G01N2035/0429 ,  G01N2201/0642 ,  G01N2201/0648 ,  Y10T436/113332 ,  Y10T436/114165

Abstract: A diagnostic analyzer includes a track, a light-blocking member, a motor, and an optical testing device. The track moves a reaction vessel held by the track. The light-blocking member is disposed adjacent to the track. The light-blocking member moves from a first position apart from the track to a second position closer to the track. When the light-blocking member is disposed in the first position a sample contained within the reaction vessel held by the track is exposed to light. When the light-blocking member is disposed in the second position the sample contained within the reaction vessel held by the track is blocked from exposure to the light. The motor moves the light-blocking member between the first and the second positions. The optical testing device is disposed adjacent to the track for optically testing the sample contained within the reaction vessel.

Abstract translation: 诊断分析仪包括轨道，遮光构件，电动机和光学测试装置。 轨道移动由轨道保持的反应容器。 遮光构件邻近轨道设置。 遮光构件从远离轨道的第一位置移动到靠近轨道的第二位置。 当遮光构件设置在第一位置时，容纳在由轨道保持的反应容器内的样品暴露于光。 当遮光构件设置在第二位置时，包含在由轨道保持的反应容器内的样品被阻挡以暴露于光。 电动机在第一和第二位置之间移动遮光构件。 光学测试装置邻近轨道设置，用于光学测试包含在反应容器内的样品。

公开(公告)号：WO2014144825A2

公开(公告)日：2014-09-18

申请号：PCT/US2014029399

申请日：2014-03-14

Applicant: ABBOTT LAB

Inventor： DONOHUE JOSEPH P ,  RAI SURYA PRATAP

CPC classification number: B01L3/52 ,  B01L3/523 ,  B01L9/50 ,  B01L2200/023 ,  B01L2200/025 ,  B01L2300/041 ,  G01N35/1002 ,  G01N2035/00524

Abstract: A reagent manager for a diagnostic analyzer system includes a reagent manager housing, a high-speed reagent bottle spinning device, a processor, and a memory. The reagent manager housing is for housing reagent bottles. The high-speed reagent bottle spinning device is disposed within the reagent manager housing for spinning at least one of the reagent bottles. The processor is in electronic communication with the high-speed reagent bottle spinning device. The memory is in electronic communication with the processor. The memory includes programming code for execution by the processor. The programming code is configured to spin the high-speed reagent bottle spinning device to spin the at least one reagent bottle to remove microparticles from a bottom surface of a septum of the at least one reagent bottle.

Abstract translation: 用于诊断分析仪系统的试剂管理器包括试剂管理器壳体，高速试剂瓶旋转装置，处理器和存储器。 试剂管理器外壳用于容纳试剂瓶。 高速试剂瓶纺纱装置设置在试剂管理器壳体内以旋转至少一个试剂瓶。 处理器与高速试剂瓶纺纱装置进行电子通讯。 存储器与处理器进行电子通信。 存储器包括用于由处理器执行的编程代码。 编程代码被配置为旋转高速试剂瓶旋转装置以旋转至少一个试剂瓶以从至少一个试剂瓶的隔膜的底表面去除微粒。

公开(公告)号：EP2972219A4

公开(公告)日：2016-11-02

申请号：EP14763589

申请日：2014-03-14

Applicant: ABBOTT LAB

Inventor： DONOHUE JOSEPH P ,  RAI SURYA PRATAP

IPC: G01N35/10 ,  B01L3/00 ,  B01L9/00 ,  G01N35/00

CPC classification number: B01L3/52 ,  B01L3/523 ,  B01L9/50 ,  B01L2200/023 ,  B01L2200/025 ,  B01L2300/041 ,  G01N35/1002 ,  G01N2035/00524

Abstract: A reagent manager for a diagnostic analyzer system includes a reagent manager housing, a high-speed reagent bottle spinning device, a processor, and a memory. The reagent manager housing is for housing reagent bottles. The high-speed reagent bottle spinning device is disposed within the reagent manager housing for spinning at least one of the reagent bottles. The processor is in electronic communication with the high-speed reagent bottle spinning device. The memory is in electronic communication with the processor. The memory includes programming code for execution by the processor. The programming code is configured to spin the high-speed reagent bottle spinning device to spin the at least one reagent bottle to remove microparticles from a bottom surface of a septum of the at least one reagent bottle.

Abstract translation: 用于诊断分析仪系统的试剂管理器包括试剂管理器壳体，高速试剂瓶旋转装置，处理器和存储器。 试剂管理器外壳用于容纳试剂瓶。 高速试剂瓶纺纱装置设置在试剂管理器壳体内以旋转至少一个试剂瓶。 处理器与高速试剂瓶纺纱装置进行电子通讯。 存储器与处理器进行电子通信。 存储器包括用于由处理器执行的编程代码。 编程代码被配置为旋转高速试剂瓶旋转装置以旋转至少一个试剂瓶以从至少一个试剂瓶的隔膜的底表面去除微粒。

公开(公告)号：CA1335383C

公开(公告)日：1995-04-25

申请号：CA607330

申请日：1989-08-02

Applicant: ABBOTT LAB

Inventor： DONOHUE JOSEPH P ,  BAILEY MARK W ,  MATTIMIRO CHRISTOPHER N

IPC: G01N35/00 ,  B01L3/00 ,  G01N21/86 ,  G01N35/10 ,  G01N33/53 ,  G01N35/02 ,  G01N21/47

Abstract: A semi-automated biological sample analyzer and subsystems are provided to simultaneously perform a plurality of enzyme immuno assays for himan IgE class antibodies specific to a panel of preselected allergens in each of a plurality of biological samples. A carousel is provided to position and hold a plurality of reaction cartridges. Each reaction cartridge includes a plurality of isolated test sites formed in a two dimensional array in a solid phase binding layer contained within a reaction well which is adapted to contain a biological sample to be assayed. The carousel and cartridges contain structures which cooperate to precisely position the cartridges in each of three separate dimensions so that each cartridge is positioned uniformly. An optical reader operating on a principle of diffuse reflectance is provided to read the results of the assays from each test site of each cartridge. Also provided is a subsystem which provides predetermined lot-specific assay calibration data which is useful for normalizing the results of various assays with respect to predetermined common standard values.