公开(公告)号：HRP20120251T1

公开(公告)日：2012-07-31

申请号：HRP20120251

申请日：2012-03-19

Applicant: ABBOTT LAB

Inventor： MARLON D COWART ,  MINGHUA SUN ,  CHEN ZHAO ,  GUO ZHU ZHENG

IPC: C07D417/04 ,  A61K31/428 ,  A61K51/04 ,  A61P9/10 ,  C07D277/64 ,  C07D417/08 ,  C07D417/12 ,  C07D487/04

Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).

公开(公告)号：MXPA04008073A

公开(公告)日：2004-11-26

申请号：MXPA04008073

申请日：2003-02-11

Applicant: ABBOTT LAB

Inventor： GUO ZHU ZHENG

IPC: A61K31/404 ,  A61K31/416 ,  A61K31/47 ,  A61K31/472 ,  A61K31/496 ,  A61K31/5377 ,  A61K31/541 ,  C07D209/08 ,  C07D217/02 ,  C07D217/22 ,  C07D217/24 ,  C07D217/26 ,  C07D231/56 ,  C07D237/28 ,  C07D401/12 ,  C07D405/12 ,  C07D521/00 ,  A61K31/502

Abstract: Se describen compuestos de la formula (I), los cuales son antagonistas novedosos de VR1 que son utiles en el tratamiento de dolor, hiperalgesia termica inflamatoria, incontinencia urinaria y sobreactividad de la vejiga.(ver formula I).