公开(公告)号：AT224355T

公开(公告)日：2002-10-15

申请号：AT97936999

申请日：1997-07-23

Applicant: ABBOTT LAB

Inventor： MAZER TERRY BRUCE ,  ANDERSON STEVEN N ,  GUZMAN-HARTY MELINDA ,  HILTY MILO DUANE ,  LEE THERESA SIU ,  SHALLER JOSEPH ,  LIU JIN-ZHOU

IPC: A61P31/12 ,  A61K31/225 ,  A61P31/04 ,  C07C69/70

Abstract: The present invention provides water-miscible lipid derivatives effective to inhibit the infectious activity of pathogenic microorganisms. Preferred water-miscible lipid derivatives are diacetyltartaric acid esters of monoglycerides wherein 90 percent or more of the fatty acid content is accounted for by a single fatty acid. The fatty acid component preferably contains from 8 to 24 and, more preferably, from about 10 to about 20 carbon atoms. The fatty acid can be saturated, unsaturated or hydroxylated.