公开(公告)号：JPH01321365A

公开(公告)日：1989-12-27

申请号：JP11718289

申请日：1989-05-10

Applicant: ABBOTT LAB

Inventor： RICHIYAADO EICHI DETSUKAA ,  JIYON EI UEA

IPC: G01N33/53 ,  G01N33/543 ,  G01N33/576

Abstract: PURPOSE: To avoid detection of false-positive reaction to anti-HBc based on several criteria by employing a reducing agent in the assay. CONSTITUTION: In the immunoassay, a reducing agent is fed additionally to the assay in order to detect an anti-HBc antibody in a biological sample. More specifically, a solid phase is coated with an HBc antigen and caused to react on a sample and then a labeled anti-HBc before the quantity of labeled anti-HBc bonded with the solid phase is detected. The reducing agent is added to the sample before the solid phase is added or it is added simultaneously with the sample and solid phase. When a reducing agent is employed in the assay of anti-HBc, false-positive sample is removed without having any effect on the control value or the presence of true positive sample thus ensuring positive reaction only on anti-HBc.

公开(公告)号：JPS60250257A

公开(公告)日：1985-12-10

申请号：JP9683085

申请日：1985-05-09

Applicant: ABBOTT LAB

Inventor： AISA KEI MASHIYAWAA ,  KAREN BUI SUTATSUKUMAN ,  RICHIYAADO EICHI DETSUKAA

IPC: G01N33/53 ,  A61K39/00 ,  C12Q1/00 ,  G01N33/532 ,  G01N33/543 ,  G01N33/576

公开(公告)号：JPS5522186A

公开(公告)日：1980-02-16

申请号：JP9434279

申请日：1979-07-26

Applicant: ABBOTT LAB

Inventor： CHIYANGUUMEI RINGU ,  RICHIYAADO EICHI DETSUKAA ,  RUBIN CHIYAAREZU

IPC: G01N33/53 ,  A61K39/29 ,  A61K39/44 ,  G01N33/543 ,  G01N33/576 ,  G01N33/68