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公开(公告)号:JPH0259127B2
公开(公告)日:1990-12-11
申请号:JP33031487
申请日:1987-12-28
Applicant: ABBOTT LAB
Inventor: ROBAATO ROTSUTEMAN
IPC: A61K31/505 , A61K9/20 , A61K31/495 , A61P9/12 , C07D215/00 , C07D403/04 , C07D405/12 , C07D405/14
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公开(公告)号:JPS63211229A
公开(公告)日:1988-09-02
申请号:JP33031487
申请日:1987-12-28
Applicant: ABBOTT LAB
Inventor: ROBAATO ROTSUTEMAN
IPC: A61K31/505 , A61K9/20 , A61K31/495 , A61P9/12 , C07D215/00 , C07D403/04 , C07D405/12 , C07D405/14
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3.
公开(公告)号:JPS5427588A
公开(公告)日:1979-03-01
申请号:JP8778778
申请日:1978-07-20
Applicant: ABBOTT LAB
Inventor: ROBAATO ROTSUTEMAN
IPC: C07D405/12 , A61K31/505 , A61P9/12 , C07D405/14
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公开(公告)号:JPH0231078B2
公开(公告)日:1990-07-11
申请号:JP8778778
申请日:1978-07-20
Applicant: ABBOTT LAB
Inventor: ROBAATO ROTSUTEMAN
IPC: C07D405/12 , A61K31/505 , A61P9/12 , C07D405/14
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公开(公告)号:JPS5480405A
公开(公告)日:1979-06-27
申请号:JP13634678
申请日:1978-11-07
Applicant: ABBOTT LAB
Inventor: ANII BAAROU RAMUZEI , DEBITSUDO SADEYUUSU GAZETSUKU , ROBAATO ROTSUTEMAN , DERUBAATO AARU RIYUUKU , CHIAARANGU HATSUSHI , UIRIAMU DEI REAZEMU
IPC: A61K9/08 , A61K31/715 , C13K1/06
Abstract: High calorie solutions of low molecular weight glucose polymer mixtures useful for intravenous administration, preferably via a peripheral vein, are disclosed. Methods of preparing the solutions and their preferred rate of infusion at less than 5 mg./min./kg. of patient body weight are also disclosed. The solutions can be isotonic to human blood at 20-50% W/V as the glucose polymer mixtures have an average degree of polymerization ranging from 4 to 10. At the preferred rate of infusion high utilization of the glucose polymers infused occurs in human patients, including diabetics. The utilization can be further enhanced by concomitant injections of insulin. The solutions can be administered concomitantly with amino acids, lipid emulsions, vitamins and electrolytes.
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