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    Device for detecting analyte and managing therapeutic substance
    1.
    发明专利
    Device for detecting analyte and managing therapeutic substance 有权
    用于检测分析物和管理治疗药物的装置

    公开(公告)号：JP2006122689A

    公开(公告)日：2006-05-18

    申请号：JP2005324355

    申请日：2005-11-09

    Applicant: Abbott Lab ,  アボット・ラボラトリーズAbbott Laboratories

    Inventor： HENNING TIMOTHY P ,  SHAIN ERIC B ,  KHALIL GAMAL ,  ELSTROM TUAN A

    IPC: A61B5/1459 ,  G01N27/28 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/15 ,  A61B5/157 ,  A61B10/00 ,  A61M1/36 ,  A61M5/00 ,  G01N21/35

    CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/6848

    Abstract: PROBLEM TO BE SOLVED: To provide a technique for measuring glucose capable of minimizing and removing pain and inconvenience of a patient. SOLUTION: The subject device for directly administering a medicine to the patient's body includes a sampling needle (12), a sensor (14) which is contained in the sampling needle and detects an analyte to become an object in the body fluid, an analyzing means (16) for receiving and processing the signal from the sensor, a control device which receives the signal from the analyzing means and sends the signal to an injection actuator, and a syringe which administers a necessary amount of a medicine to become the object corresponding to the injection actuator. COPYRIGHT: (C)2006,JPO&NCIPI

    Abstract translation: 要解决的问题：提供一种能够最小化并消除患者疼痛和不便的葡萄​​糖测定技术。 解决方案：用于向患者身体直接施用药物的主体装置包括采样针（12），传感器（14），其被包含在采样针中并且检测分析物成为体液中的物体， 用于接收和处理来自传感器的信号的分析装置（16），控制装置，其接收来自分析装置的信号并将该信号发送到注射致动器;以及注射器，其将需要量的药物施加到 物体对应于喷射致动器。 版权所有（C）2006，JPO＆NCIPI

    Method and system for analyzing reaction using information system
    3.
    发明专利
    Method and system for analyzing reaction using information system 有权
    使用信息系统分析反应的方法和系统

    公开(公告)号：JP2012231791A

    公开(公告)日：2012-11-29

    申请号：JP2012128624

    申请日：2012-06-06

    Applicant: Abbott Lab ,  アボット・ラボラトリーズAbbott Laboratories

    Inventor： CLEMENS JOHN M ,  SHAIN ERIC B ,  JENG TZYY-WEN ,  SCHNEIDER GEORGE J

    IPC: C12Q1/68

    CPC classification number: G06F19/22 ,  C12Q1/68 ,  C12Q1/6851 ,  C12Q1/686 ,  C12Q2561/113 ,  C12Q2545/101 ,  C12Q2537/165

    Abstract: PROBLEM TO BE SOLVED: To provide an information system performing measurements regarding to chemical and or biological reaction, and a method using the same.SOLUTION: There are provided a method and system for determining the quantity of an analyte initially present in a chemical and or biological reaction as well as a computer implemented method and system to automate a portion of the analysis comprising mathematical or graphical analysis of an amplification reaction. The amount of the target present in the test sample can be objectively quantified without calculating variable threshold values and Ct values. The information usable in determining the degree of inhibition in the reaction can be obtained by the shape analysis of the PCR amplification curve of the data in cycles after Ct, etc., which are ignored before.

    Abstract translation: 要解决的问题：提供对化学和/或生物反应进行测量的信息系统及其使用方法。 解决方案：提供了用于确定最初存在于化学和/或生物反应中的分析物的量的方法和系统以及计算机实现的方法和系统，以使分析的一部分自动化，包括数学或图形分析 扩增反应。 可以客观量化测试样本中存在的目标量，而不需要计算可变阈值和Ct值。 用于确定反应抑制程度的信息可以通过以下忽略的Ct等之后的循环数据的PCR扩增曲线的形状分析来获得。 版权所有（C）2013，JPO＆INPIT

    Apparatus and method for handling fluid for analysis
    7.
    发明专利
    Apparatus and method for handling fluid for analysis 有权
    用于处理流体的分析装置和方法

    公开(公告)号：JP2010151849A

    公开(公告)日：2010-07-08

    申请号：JP2010086633

    申请日：2010-04-05

    Applicant: Abbott Lab ,  アボット・ラボラトリーズAbbott Laboratories

    Inventor： LOWREY MICHAEL ,  SAFAR SCOTT ,  DUNN CHADWICK M ,  GALITZ CHARLES M ,  TOTH JULIUS J ,  KUKLA RONALD E ,  HERCHENBACH STEPHEN ,  SHAIN ERIC B

    IPC: G01N35/10 ,  B01L3/00 ,  B01L3/14 ,  B67D99/00 ,  G01N1/00 ,  G01N35/00 ,  G01N35/02

    CPC classification number: G01N35/1004 ,  B01L3/50255 ,  B01L3/5082 ,  B01L99/00 ,  B01L2200/0668 ,  B01L2400/049 ,  B01L2400/0655 ,  B01L2400/0688 ,  G01N35/0098 ,  G01N35/1065 ,  Y10T137/0391 ,  Y10T137/0396 ,  Y10T436/25375 ,  Y10T436/2575

    Abstract: PROBLEM TO BE SOLVED: To provide a reaction vessel with a bottom drain opening supporting a selected unpressured head of fluid by the surface tension of the fluid. SOLUTION: A device processing zone includes a support for spaced rows of reaction vessels, passages communicating with their drain openings of supported vessels, and a pressure source for selectively draining fluid through the drain openings. Generally, horizontal bar magnets are supported for selected vertical movement between the vessel rows. A dispensing head has X discharge openings selectively positionable over X selected reaction vessels. A metering pump mechanism selectively meters X selected quantities of fluid from a bulk supply (where X is at least four), and selectively pumps the metered selected quantities through the drain openings to the selected reaction vessels. Methods of drawing fluid from the vessels using the pressure source, and moving the magnets to form a pellet of analyte are also included. COPYRIGHT: (C)2010,JPO&INPIT

    Abstract translation: 要解决的问题：为反应容器提供底部排放开口，其通过流体的表面张力支撑选定的未压缩流体的头部。 解决方案：设备处理区域包括支撑间隔开的反应容器列，与其支撑容器的排放开口连通的通道，以及用于选择性地通过排放开口排出流体的压力源。 通常，水平条形磁体被支撑用于在容器列之间选择的垂直运动。 分配头具有可选择性地定位在X选择的反应容器上的X个排出口。 计量泵机构选择性地从大量供应（其中X至少为四个）计量X个选定量的流体，并且通过排放开口选择性地将计量的所选量泵送到选定的反应容器。 还包括使用压力源从容器中抽取流体并移动磁体以形成分析物颗粒的方法。 版权所有（C）2010，JPO＆INPIT

    Magnetically assisted binding assay using magnetically responsive reagent
    8.
    发明专利
    Magnetically assisted binding assay using magnetically responsive reagent 有权
    使用磁性反应试剂进行磁性辅助测定

    公开(公告)号：JP2009204617A

    公开(公告)日：2009-09-10

    申请号：JP2009107323

    申请日：2009-04-27

    Applicant: Abbott Lab ,  アボット・ラボラトリーズAbbott Laboratories

    Inventor： ROHR THOMAS E ,  ELSTROM TUAN A ,  HOWARD LAWRENCE V ,  SHAIN ERIC B

    IPC: G01N27/72 ,  G01N33/553 ,  G01N33/543

    CPC classification number: G01N33/54333 ,  G01N33/54366 ,  Y10S436/806 ,  Y10S977/773 ,  Y10S977/838 ,  Y10S977/89 ,  Y10S977/92 ,  Y10S977/96

    Abstract: PROBLEM TO BE SOLVED: To provide an assay method for qualitatively and quantitatively measuring binding between specific binding pair members utilizing the response of a magnetically responsive reagent to the influence of a magnetic field. SOLUTION: The presence of an analyte mediates whether or not the magnetically responsive reagent binds to a mobile solid phase reagent. The extent of binding modulates the response of the magnetically responsive reagent or that of the mobile solid phase reagent, or both, to the influence of a magnetic field. The response to the magnetic field of the magnetically responsive reagent, or that of the mobile solid phase reagent, is measured to accurately determine the presence or amount of analyte contained in a test sample. Various devices are utilized to carry out the assay method. COPYRIGHT: (C)2009,JPO&INPIT

    Abstract translation: 要解决的问题：提供一种用于定性和定量测量特异性结合对成员之间利用磁响应试剂对磁场影响的响应的测定方法。 解决方案：分析物的存在介导了磁性响应试剂是否结合流动固相试剂。 结合程度将磁响应试剂或可移动固相试剂或两者的响应调节到磁场的影响。 测量对磁响应试剂或移动固相试剂的磁场的响应，以准确地确定测试样品中包含的分析物的存在或量。 利用各种装置进行测定方法。 版权所有（C）2009，JPO＆INPIT

    Magnetically assisted binding assay utilizing magnetically responsive reagent
    9.
    发明专利
    Magnetically assisted binding assay utilizing magnetically responsive reagent 有权
    使用磁性反应试剂的磁辅助结合测定

    公开(公告)号：JP2008003083A

    公开(公告)日：2008-01-10

    申请号：JP2007148109

    申请日：2007-06-04

    Applicant: Abbott Lab ,  アボット・ラボラトリーズAbbott Laboratories

    Inventor： ROHR THOMAS E ,  ELSTROM TUAN A ,  HOWARD LAWRENCE V ,  SHAIN ERIC B

    IPC: G01N33/553 ,  G01N33/543

    CPC classification number: G01N33/54333 ,  G01N33/54366 ,  Y10S436/806 ,  Y10S977/773 ,  Y10S977/838 ,  Y10S977/89 ,  Y10S977/92 ,  Y10S977/96

    Abstract: PROBLEM TO BE SOLVED: To provide an assay method utilizing the response of a magnetically responsive reagent to the influence of a magnetic field to qualitatively or quantitatively measure binding between specific binding pair members. SOLUTION: The presence of an analyte is determined depending on whether or not the magnetically responsive reagent binds to a mobile solid phase reagent. The extent of binding will modulate the response of the magnetically responsive reagent or that of the mobile solid phase reagent, or both, to the influence of a magnetic field. Hence, measuring the response to the magnetic field of the magnetically responsive reagent, or that of the mobile solid phase reagent, enables the accurate determination of the presence or amount of analyte contained in a test sample. Various devices for carrying out the assay method are utilized. COPYRIGHT: (C)2008,JPO&INPIT

    Abstract translation: 要解决的问题：提供使用磁响应试剂对磁场影响的响应的测定方法，以定性或定量测量特异性结合对成员之间的结合。 解决方案：分析物的存在取决于磁响应试剂是否与可移动固相试剂结合。 结合的程度将调节磁响应试剂或可移动固相试剂或两者的响应对磁场的影响。 因此，测量对磁响应试剂或可移动固相试剂的磁场的响应使得能够准确地确定测试样品中包含的分析物的存在或量。 利用用于进行测定方法的各种装置。 版权所有（C）2008，JPO＆INPIT

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