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    INHIBITION OF ROTAVIRUS INFECTION WITH CARRAGEENAN OR DEXTRAN SULFATE
    2.
    发明申请
    INHIBITION OF ROTAVIRUS INFECTION WITH CARRAGEENAN OR DEXTRAN SULFATE 审中-公开
    用卡罗林或代谢硫酸盐抑制罗非鱼感染

    公开(公告)号：WO1996030027A1

    公开(公告)日：1996-10-03

    申请号：PCT/US1996003902

    申请日：1996-03-22

    Applicant: ABBOTT LABORATORIES

    Inventor： ABBOTT LABORATORIES ,  ANDERSON, Steven, Neal ,  SCHALLER, Joseph, Paul ,  MAZER, Terrence, Bruce ,  KIRCHNER, Stephen, John

    IPC: A61K31/725

    CPC classification number: A61K31/737 ,  A61K31/731

    Abstract: A method is provided for inhibiting rotavirus infection of human cells by treating the rotavirus with a sulfated polysaccharide. Sulfated polysaccharides include carrageenan and dextran sulfate. The most effective agent in inhibiting cellular rotavirus infection is lambda-carrageenan, which may be formulated in a liquid and ingested enterally. A composition containing lambda-carrageenan is an aspect of the invention.

    Abstract translation: 提供了通过用硫酸化多糖处理轮状病毒来抑制人类细胞的轮状病毒感染的方法。 硫酸化多糖包括角叉菜胶和硫酸葡聚糖。 抑制细胞轮状病毒感染的最有效的药剂是λ-角叉菜胶，其可以配制成液体并肠内摄入。 含有λ-角叉菜胶的组合物是本发明的一个方面。

    INHIBITION OF ATTACHMENT OF H. INFLUENZAE TO HUMAN CELLS
    3.
    发明申请
    INHIBITION OF ATTACHMENT OF H. INFLUENZAE TO HUMAN CELLS 审中-公开
    抑制H.HIV对人类细胞的影响

    公开(公告)号：WO1995032728A1

    公开(公告)日：1995-12-07

    申请号：PCT/US1995003789

    申请日：1995-04-18

    Applicant: ABBOTT LABORATORIES

    Inventor： ABBOTT LABORATORIES ,  MUKERJI, Pradip ,  SEO, Amanda, Eun-Yeong ,  ANDERSON, Steven, Neal ,  HARVEY, Linda, Ann

    IPC: A61K38/17

    CPC classification number: C07K14/4732 ,  A23L33/19 ,  A61K38/018 ,  A61K38/1709

    Abstract: The attachment of H. influenzae to human cells, such as oropharyngeal cells, may be inhibited by native human beta -casein, a recombinant form of human beta -casein, and hydrolysates of both. The human beta -casein or hydrolysate may be contained in a liquid enteral nutritional product such as an infant formula. The enteral nutritional product may be used, for example, in the prevention and treatment of otitis media in infants. The human beta -casein or hydrolysate may also be administered as a throat spray or nasally using drops or a spray.

    Abstract translation: 流感嗜血杆菌对人细胞如口咽细胞的附着可被天然人β-酪蛋白，人β-酪蛋白的重组形式和两者的水解产物所抑制。 人β-酪蛋白或水解产物可以包含在液体肠内营养产品如婴儿配方奶粉中。 肠内营养产品可用于例如预防和治疗婴幼儿中耳炎。 人类β-酪蛋白或水解产物也可以作为喉部喷雾剂或使用滴剂或喷雾剂鼻部施用。

    PRODUCT FOR INHIBITION OF ATTACHMENT OF H. INFLUENZAE TO HUMAN CELLS
    4.
    发明申请
    PRODUCT FOR INHIBITION OF ATTACHMENT OF H. INFLUENZAE TO HUMAN CELLS 审中-公开
    用于抑制H淋巴细胞对人细胞的附着的产品

    公开(公告)号：WO1997026320A2

    公开(公告)日：1997-07-24

    申请号：PCT/US1996017971

    申请日：1996-11-06

    Applicant: ABBOTT LABORATORIES

    Inventor： ABBOTT LABORATORIES ,  MUKERJI, Pradip ,  THURMOND, Jennifer, Marie ,  HANSSON, Lennart ,  BAXTER, Jennifer, Harris ,  HARDS, Robert, George ,  LEONARD, Amanda, Eun-Yeong ,  ANDERSON, Steven, Neal ,  HARVEY, Linda, Ann

    IPC: C12N00/00

    CPC classification number: A61K38/1709

    Abstract: A product is provided for inhibiting the attachment of H. influenzae to human cells, such as pharyngeal cells, by contacting the bacilli with phosphorylated recombinant human beta -casein that have at least 3 phosphate groups. The product containing phosphorylated recombinant human beta -casein may be a liquid enteral nutritional product such as infant formula. The enteral nutritional product may be used for the prevention and treatment of otitis media in infants. The phosphorylated recombinant human beta -casein may also be administered as a throat spray or used in nose drops or a spray.

    Abstract translation: 通过使杆菌与具有至少3个磷酸基团的磷酸化重组人β-酪蛋白接触，提供了用于抑制流感嗜血杆菌与人细胞如咽细胞的连接的产物。 含有磷酸化重组人β-酪蛋白的产品可以是液体肠内营养产品，例如婴儿配方食品。 肠内营养产品可用于预防和治疗婴幼儿中耳炎。 磷酸化重组人β-酪蛋白也可以作为咽喉喷雾剂施用或用于鼻滴或喷雾剂中。

    INHIBITION OF INFECTION OF MAMMALIAN CELLS BY RESPIRATORY SYNCYTIAL VIRUS
    5.
    发明申请
    INHIBITION OF INFECTION OF MAMMALIAN CELLS BY RESPIRATORY SYNCYTIAL VIRUS 审中-公开
    通过呼吸道同源性病毒抑制MAMMALIAN细胞的感染

    公开(公告)号：WO1995032727A1

    公开(公告)日：1995-12-07

    申请号：PCT/US1995003628

    申请日：1995-03-27

    Applicant: ABBOTT LABORATORIES

    Inventor： ABBOTT LABORATORIES ,  MUKERJI, Pradip ,  SEO, Amanda, Eun-Yeong ,  ANDERSON, Steven, Neal ,  SCHALLER, Joseph, Paul

    IPC: A61K38/17

    CPC classification number: A61K38/018 ,  A23L33/19 ,  C07K14/4732

    Abstract: The infection of mammalian cells by RSV may be inhibited by native human beta -casein, a recombinant form of human beta -casein, and hydrolysates of both. The human beta -casein or hydrolysate may be contained in a liquid enteral nutritional product such as an infant formula. The enteral nutritional product may be used, for example, in the prevention and treatment of respiratory tract infection in infants. The human beta -casein or hydrolysate may also be administered as a throat spray or nasally using drops or a spray.

    Abstract translation: RSV的哺乳动物细胞感染可被天然人β-酪蛋白，人β-酪蛋白的重组形式和两者的水解产物所抑制。 人β-酪蛋白或水解产物可以包含在液体肠内营养产品如婴儿配方奶粉中。 肠内营养产品可用于例如预防和治疗婴儿呼吸道感染。 人类β-酪蛋白或水解产物也可以作为喉部喷雾剂或使用滴剂或喷雾剂鼻部施用。

    PRODUCT AND METHOD FOR PREVENTING RESPIRATORY VIRUS INFECTION
    7.
    发明公开
    PRODUCT AND METHOD FOR PREVENTING RESPIRATORY VIRUS INFECTION 无效
    组合物和方法为了预防感染由病毒呼吸

    公开(公告)号：EP0808173A2

    公开(公告)日：1997-11-26

    申请号：EP96904605.0

    申请日：1996-02-08

    Applicant: ABBOTT LABORATORIES

    Inventor： HILTY, Milo, Duane ,  ANDERSON, Steven, Neal ,  SCHALLER, Joseph, Paul ,  LIU, Jin-Zhou

    IPC: C02F1 ,  C02F9

    CPC classification number: C07K16/1027

    Abstract: A device for preparing drinking water in the form of a transportable table and travelling device with an interchangeable filter cartridge (24), a u/v lamp (25), an untreated water container (21) and a pure water container (28). The u/v lamp (25) is arranged above the open pure water container (28) and radiates directly thereinto. The u/v lamp (25), the filter cartridge (24) and the electrical components for operating the u/v lamp (25) or to control and monitor the device are combined into a structural unit which, during operation, is placed on the pure water container (28) and carries the preferably removable untreated water container (21) on its top. It is particularly easily transported if the unit (23) can be inserted into the untreated water container (21) and both components together can be inserted into the pure water container (28). The unit also has operating and indicating components to control the process and devices for preventing incorrect operation.

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