公开(公告)号：WO1998004157A1

公开(公告)日：1998-02-05

申请号：PCT/US1997012960

申请日：1997-07-23

Applicant: ABBOTT LABORATORIES

Inventor： ABBOTT LABORATORIES ,  SCHALLER, Joseph ,  ANDERSON, Steven, N. ,  MAZER, Terry, B. ,  HILTY, Milo, Duane ,  GUZMAN-HARTY, Melinda ,  LEE, Theresa, Siu-Ling, Wai ,  BOWMAN, Tammy, Marie ,  LAMM, Jill, M. ,  LIU, Jin-Zhou

IPC: A23L01/30

CPC classification number: A61K31/23 ,  A23L33/12

Abstract: A nutritional formulation containing an amount of diacetyltartaric acid esters of mono- and diglycerides effective to inhibit the infectious activity of pathogenic microorganisms is provided. A method of inhibiting the infectious activity of pathogenic microorganisms including the step of feeding the nutritional composition to a subject is also provided.

Abstract translation: 提供了含有一定量的有效抑制病原微生物的感染活性的单甘油酯和甘油二酯的二乙酰酒石酸酯的营养制剂。 还提供了抑制致病微生物感染活性的方法，包括将营养组合物喂给受试者的步骤。

公开(公告)号：WO1996031186A2

公开(公告)日：1996-10-10

申请号：PCT/US1996001790

申请日：1996-02-08

Applicant: ABBOTT LABORATORIES

Inventor： ABBOTT LABORATORIES ,  HILTY, Milo, Duane ,  ANDERSON, Steven, Neal ,  SCHALLER, Joseph, Paul ,  LIU, Jin-Zhou

IPC: A61K00/00

CPC classification number: C07K16/1027

Abstract: A method of treating pneumonia or other respiratory disease caused by respiratory syncytial virus, adenovirus, parainfluenza virus, or influenza virus by orally administering a liquid, preferably an infant formula, containing a virus neutralizing antibody.

Abstract translation: 通过口服施用含有病毒中和抗体的液体，优选婴儿配方，治疗呼吸道合胞病毒，腺病毒，副流感病毒或流感病毒引起的肺炎或其它呼吸道疾病的方法。

公开(公告)号：WO1998004513A1

公开(公告)日：1998-02-05

申请号：PCT/US1997012879

申请日：1997-07-23

Applicant: ABBOTT LABORATORIES

Inventor： ABBOTT LABORATORIES ,  MAZER, Terry, Bruce ,  ANDERSON, Steven, N. ,  GUZMAN-HARTY, Melinda ,  HILTY, Milo, Duane ,  LEE, Theresa, Siu-Ling, Wai ,  SHALLER, Joseph ,  LIU, Jin-Zhou

IPC: C07C69/70

CPC classification number: C07C69/70

Abstract: The present invention provides water-miscible lipid derivatives effective to inhibit the infectious activity of pathogenic microorganisms. Preferred water-miscible lipid derivatives are diacetyltartaric acid esters of monoglycerides wherein 90 percent or more of the fatty acid content is accounted for by a single fatty acid. The fatty acid component preferably contains from 8 to 24 and, more preferably, from about 10 to about 20 carbon atoms. The fatty acid can be saturated, unsaturated or hydroxylated.

Abstract translation: 本发明提供了有效抑制致病微生物感染活性的水混溶性脂质衍生物。 优选的水混溶性脂质衍生物是甘油单酯的二乙酰酒石酸酯，其中90％或更多的脂肪酸含量由单一脂肪酸占据。 脂肪酸组分优选含有8至24个，更优选约10至约20个碳原子。 脂肪酸可以是饱和的，不饱和的或羟基化的。

公开(公告)号：EP0808173A2

公开(公告)日：1997-11-26

申请号：EP96904605.0

申请日：1996-02-08

Applicant: ABBOTT LABORATORIES

Inventor： HILTY, Milo, Duane ,  ANDERSON, Steven, Neal ,  SCHALLER, Joseph, Paul ,  LIU, Jin-Zhou

IPC: C02F1 ,  C02F9

CPC classification number: C07K16/1027

Abstract: A device for preparing drinking water in the form of a transportable table and travelling device with an interchangeable filter cartridge (24), a u/v lamp (25), an untreated water container (21) and a pure water container (28). The u/v lamp (25) is arranged above the open pure water container (28) and radiates directly thereinto. The u/v lamp (25), the filter cartridge (24) and the electrical components for operating the u/v lamp (25) or to control and monitor the device are combined into a structural unit which, during operation, is placed on the pure water container (28) and carries the preferably removable untreated water container (21) on its top. It is particularly easily transported if the unit (23) can be inserted into the untreated water container (21) and both components together can be inserted into the pure water container (28). The unit also has operating and indicating components to control the process and devices for preventing incorrect operation.

公开(公告)号：EP0918742B1

公开(公告)日：2002-09-18

申请号：EP97936999.8

申请日：1997-07-23

Applicant: Abbott Laboratories

Inventor： MAZER, Terry, Bruce ,  ANDERSON, Steven, N. ,  GUZMAN-HARTY, Melinda ,  HILTY, Milo, Duane ,  LEE, Theresa, Siu-Ling, Wai ,  SHALLER, Joseph ,  LIU, Jin-Zhou

IPC: C07C69/70

CPC classification number: C07C69/70

Abstract: The present invention provides water-miscible lipid derivatives effective to inhibit the infectious activity of pathogenic microorganisms. Preferred water-miscible lipid derivatives are diacetyltartaric acid esters of monoglycerides wherein 90 percent or more of the fatty acid content is accounted for by a single fatty acid. The fatty acid component preferably contains from 8 to 24 and, more preferably, from about 10 to about 20 carbon atoms. The fatty acid can be saturated, unsaturated or hydroxylated.

公开(公告)号：EP0920262A1

公开(公告)日：1999-06-09

申请号：EP97934281.0

申请日：1997-07-23

Applicant: Abbott Laboratories

Inventor： SCHALLER, Joseph ,  ANDERSON, Steven, N. ,  MAZER, Terry, B. ,  HILTY, Milo, Duane ,  GUZMAN-HARTY, Melinda ,  LEE, Theresa, Siu-Ling, Wai ,  BOWMAN, Tammy, Marie ,  LAMM, Jill, M. ,  LIU, Jin-Zhou

IPC: A23L1 ,  A61K31 ,  A61P31

CPC classification number: A61K31/23 ,  A23L33/12

Abstract: A nutritional formulation containing an amount of diacetyltartaric acid esters of mono- and diglycerides effective to inhibit the infectious activity of pathogenic microorganisms is provided. A method of inhibiting the infectious activity of pathogenic microorganisms including the step of feeding the nutritional composition to a subject is also provided.

公开(公告)号：EP0808173B1

公开(公告)日：2002-08-28

申请号：EP96904605.1

申请日：1996-02-08

Applicant: ABBOTT LABORATORIES

Inventor： HILTY, Milo, Duane ,  ANDERSON, Steven, Neal ,  SCHALLER, Joseph, Paul ,  LIU, Jin-Zhou

IPC: A61K39/00

CPC classification number: C07K16/1027

Abstract: A method of treating pneumonia or other respiratory disease caused by respiratory syncytial virus, adenovirus, parainfluenza virus, or influenza virus by orally administering a liquid, preferably an infant formula, containing a virus neutralizing antibody.

公开(公告)号：EP0918742A1

公开(公告)日：1999-06-02

申请号：EP97936999.0

申请日：1997-07-23

Applicant: Abbott Laboratories

Inventor： MAZER, Terry, Bruce ,  ANDERSON, Steven, N. ,  GUZMAN-HARTY, Melinda ,  HILTY, Milo, Duane ,  LEE, Theresa, Siu-Ling, Wai ,  SHALLER, Joseph ,  LIU, Jin-Zhou

IPC: A61P31 ,  A61K31 ,  C07C69

CPC classification number: C07C69/70

Abstract: The present invention provides water-miscible lipid derivatives effective to inhibit the infectious activity of pathogenic microorganisms. Preferred water-miscible lipid derivatives are diacetyltartaric acid esters of monoglycerides wherein 90 percent or more of the fatty acid content is accounted for by a single fatty acid. The fatty acid component preferably contains from 8 to 24 and, more preferably, from about 10 to about 20 carbon atoms. The fatty acid can be saturated, unsaturated or hydroxylated.