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1.发明申请1,3-DISUBSTITUTED AND 1,3,3,-TRISUBSTITUTED PYRROLIDINES AS HISTAMINE-3 RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS 审中-公开作为组胺-3受体配体及其治疗应用的1,3 - 取代的1,3,3 - 衍生吡咯烷
公开(公告)号：WO2003059341A1
公开(公告)日：2003-07-24
申请号：PCT/US2003/000703
申请日：2003-01-10
Applicant: ABBOTT LABORATORIES
Inventor： BENNANI, Youssef, L. , FAGHIH, Ramin , DWIGHT, Wesley, J. , VASUDEVAN, Anil , CONNER, Scott, E.
IPC: A61K31/40
CPC classification number: C07D403/04 , C07D207/12 , C07D207/14 , C07D207/24 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07D417/14
Abstract: Compounds of formula I, are useful in treating diseases or conditions prevented by or ameliorated with histamine-3 receptor ligands. Also disclosed are histamine-3 receptor ligand compositions and methods of antagonizing or agonizing histamine-3 receptors.
Abstract translation: 式I化合物可用于治疗用组胺-3受体配体预防或改善的疾病或病症。 还公开了组胺-3受体配体组合物和拮抗或激动组胺3受体的方法。
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2.发明公开1,3-DISUBSTITUTED AND 1,3,3-TRISUBSTITUTED PYRROLIDINES AS HISTAMINE-3 RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS 有权1.3二取代和1,3,3-三 - 取代的吡咯烷作为组胺-3受体和治疗用途配体
公开(公告)号：EP1301480A1
公开(公告)日：2003-04-16
申请号：EP01952653.2
申请日：2001-07-11
Applicant: ABBOTT LABORATORIES
Inventor： BENNANI, Youssef, L. , FAGHIH, Ramin , DWIGHT, Wesley, J. , VASUDEVAN, Anil , CONNER, Scott, E.
IPC: C07D207/12 , C07D207/14 , C07D207/16 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07D403/04 , C07D417/14 , A61K31/4025 , A61P9/10 , A61P25/28 , A61P29/00
CPC classification number: C07D401/12 , C07D207/12 , C07D207/14 , C07D207/16 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07D417/14
Abstract: Compounds of formula (I) are useful in treating diseases or conditions prevented by or ameliorated with histamine-3 receptor ligands. Also disclosed are histamine-3 receptor ligand compositions and methods of antagonizing or agonizing histamine-3 receptors.
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3.发明授权1,3-DISUBSTITUTED AND 1,3,3-TRISUBSTITUTED PYRROLIDINES AS HISTAMINE-3 RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS 有权1.3二取代和1,3,3-三 - 取代的吡咯烷作为组胺-3受体和治疗用途配体
公开(公告)号：EP1301480B1
公开(公告)日：2007-09-12
申请号：EP01952653.2
申请日：2001-07-11
Applicant: ABBOTT LABORATORIES
Inventor： BENNANI, Youssef, L. , FAGHIH, Ramin , DWIGHT, Wesley, J. , VASUDEVAN, Anil , CONNER, Scott, E.
IPC: C07D207/12 , C07D207/14 , C07D207/16 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07D403/04 , C07D417/14 , A61K31/4025 , A61P9/10 , A61P25/28 , A61P29/00
CPC classification number: C07D401/12 , C07D207/12 , C07D207/14 , C07D207/16 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07D417/14
Abstract: Compounds of formula (I) are useful in treating diseases or conditions prevented by or ameliorated with histamine-3 receptor ligands. Also disclosed are histamine-3 receptor ligand compositions and methods of antagonizing or agonizing histamine-3 receptors.
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4.发明公开1,3-DISUBSTITUTED AND 1,3,3,-TRISUBSTITUTED PYRROLIDINES AS HISTAMINE-3 RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS 审中-公开1.3二取代和1,3,3-三 - 取代的吡咯烷作为组胺-3受体和治疗用途配体
公开(公告)号：EP1467727A1
公开(公告)日：2004-10-20
申请号：EP03701286.1
申请日：2003-01-10
Applicant: Abbott Laboratories
Inventor： BENNANI, Youssef, L. , FAGHIH, Ramin , DWIGHT, Wesley, J. , VASUDEVAN, Anil , CONNER, Scott, E.
IPC: A61K31/40 , A61P9/10 , A61P25/28 , C07D207/14
CPC classification number: C07D403/04 , C07D207/12 , C07D207/14 , C07D207/24 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07D417/14
Abstract: Compounds of formula I, are useful in treating diseases or conditions prevented by or ameliorated with histamine-3 receptor ligands. Also disclosed are histamine-3 receptor ligand compositions and methods of antagonizing or agonizing histamine-3 receptors.
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