公开(公告)号：EP2336138A2

公开(公告)日：2011-06-22

申请号：EP10184668.1

申请日：2005-06-29

Applicant: ABBOTT LABORATORIES

Inventor： Degoey, DAvid A ,  Flosi, William J ,  Grampovnik, David J. ,  Klein, Larry L. ,  Kempf, Dale J. ,  Wang, Xiu C.

IPC: C07F9/09 ,  A61K31/661 ,  A61P35/00

CPC classification number: A61K45/06 ,  A61K31/661 ,  A61K2300/00

Abstract: A compound of the formula I, II or III is disclosed as a prodrug of an HIV protease inhibitor. Methods and compositions of inhibiting HIV protease activity and treating HIV infection are also disclosed.

Abstract translation: 公开了式I，II或III的化合物作为HIV蛋白酶抑制剂的前药。 还公开了抑制HIV蛋白酶活性和治疗HIV感染的方法和组合物。

公开(公告)号：EP2336138A3

公开(公告)日：2011-11-16

申请号：EP10184668.1

申请日：2005-06-29

Applicant: ABBOTT LABORATORIES

Inventor： Degoey, DAvid A ,  Flosi, William J ,  Grampovnik, David J. ,  Klein, Larry L. ,  Kempf, Dale J. ,  Wang, Xiu C.

IPC: C07F9/09 ,  A61K31/661 ,  A61P35/00

CPC classification number: A61K45/06 ,  A61K31/661 ,  A61K2300/00

Abstract: A compound of the formula I, II or III is disclosed as a prodrug of an HIV protease inhibitor. Methods and compositions of inhibiting HIV protease activity and treating HIV infection are also disclosed.