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1.发明申请REAGENTS AND METHODS FOR THE DETECTION AND QUANTIFICATION OF TESTOSTERONE IN FLUID SAMPLES 审中-公开流体样品中TESTOSTERONE检测和定量的试剂和方法
公开(公告)号：WO1995004283A1
公开(公告)日：1995-02-09
申请号：PCT/US1994008604
申请日：1994-08-01
Applicant: ABBOTT LABORATORIES
Inventor： ABBOTT LABORATORIES , ADAMCZYK, Maciej , CHEN, Yon-Yih , WALLING, John, A. , JAMES, Bryan, D. , ARTRIP, Sharon, G.
IPC: G01N33/74
CPC classification number: G01N33/53 , C07J1/0022 , C07K16/26 , G01N33/743 , Y02P20/55 , Y10S435/81 , Y10S435/962 , Y10S435/968 , Y10S436/817 , Y10S436/822 , Y10S530/812
Abstract: The present invention discloses novel immunogens, antibodies prepared from such immunogens, and labeled reagents useful in immunoassays for the detection and quantification of testosterone in a test sample. Also disclosed are immunoassays using these reagents and methods for synthesizing these reagents. The immunoassays are preferably microparticle enzyme immunoassays (MEIAs) and fluorescence polarization immunoassays (FPIAs). Further discloded are novel starting materials for making the above novel immunogens and labeled reagents. Methods for making the novel immunogens and labeled reagents from the novel starting materials are also disclosed.
Abstract translation: 本发明公开了由免疫原制备的新型免疫原，抗体以及用于免疫测定的标记试剂，用于检测和定量测试样品中的睾酮。 还公开了使用这些试剂的免疫测定法和合成这些试剂的方法。 免疫测定优选为微粒酶免疫测定（MEIAs）和荧光偏振免疫测定（FPIAs）。 进一步揭示了制备上述新型免疫原和标记试剂的新型起始材料。 还公开了从新型起始材料制备新型免疫原和标记试剂的方法。
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2.发明授权REAGENTS AND METHODS FOR THE DETECTION AND QUANTIFICATION OF TESTOSTERONE IN FLUID SAMPLES 失效试剂和方法检测和睾酮的液体样品定量测定方法
公开(公告)号：EP0712497B1
公开(公告)日：2001-11-07
申请号：EP94927907.9
申请日：1994-08-01
Applicant: Abbott Laboratories
Inventor： ADAMCZYK, Maciej , CHEN, Yon-Yih , WALLING, John, A. , JAMES, Bryan, D. , ARTRIP, Sharon, G.
IPC: G01N33/74 , G01N33/531 , G01N33/58 , C07K16/24 , C07J1/00 , A61K31/565 , A61K31/58
CPC classification number: G01N33/53 , C07J1/0022 , C07K16/26 , G01N33/743 , Y02P20/55 , Y10S435/81 , Y10S435/962 , Y10S435/968 , Y10S436/817 , Y10S436/822 , Y10S530/812
Abstract: The present invention discloses novel immunogens, antibodies prepared from such immunogens, and labeled reagents useful in immunoassays for the detection and quantification of testosterone in a test sample. Also disclosed are immunoassays using these reagents and methods for synthesizing these reagents. The immunoassays are preferably microparticle enzyme immunoassays (MEIAs) and fluorescence polarization immunoassays (FPIAs). Further discloded are novel starting materials for making the above novel immunogens and labeled reagents. Methods for making the novel immunogens and labeled reagents from the novel starting materials are also disclosed.
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3.发明公开REAGENTS AND METHODS FOR THE DETECTION AND QUANTIFICATION OF TESTOSTERONE IN FLUID SAMPLES 失效试剂和方法检测和睾酮的液体样品定量测定方法
公开(公告)号：EP0712497A1
公开(公告)日：1996-05-22
申请号：EP94927907.0
申请日：1994-08-01
Applicant: Abbott Laboratories
Inventor： ADAMCZYK, Maciej , CHEN, Yon-Yih , WALLING, John, A. , JAMES, Bryan, D. , ARTRIP, Sharon, G.
CPC classification number: G01N33/53 , C07J1/0022 , C07K16/26 , G01N33/743 , Y02P20/55 , Y10S435/81 , Y10S435/962 , Y10S435/968 , Y10S436/817 , Y10S436/822 , Y10S530/812
Abstract: The present invention discloses novel immunogens, antibodies prepared from such immunogens, and labeled reagents useful in immunoassays for the detection and quantification of testosterone in a test sample. Also disclosed are immunoassays using these reagents and methods for synthesizing these reagents. The immunoassays are preferably microparticle enzyme immunoassays (MEIAs) and fluorescence polarization immunoassays (FPIAs). Further discloded are novel starting materials for making the above novel immunogens and labeled reagents. Methods for making the novel immunogens and labeled reagents from the novel starting materials are also disclosed.
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