公开(公告)号：WO1997007246A1

公开(公告)日：1997-02-27

申请号：PCT/US1996013199

申请日：1996-08-14

Applicant: ABBOTT LABORATORIES

Inventor： ABBOTT LABORATORIES ,  MARSHALL, Ronald, L. ,  JOU, Cynthia ,  SIMONS, John, N. ,  LEARY, Thomas, P. ,  MUERHOFF, A., Scott ,  DESAI, Suresh, M. ,  MUSHAHWAR, Isa, K.

IPC: C12Q01/70

CPC classification number: C12Q1/707 ,  C12Q1/686 ,  Y10S435/81

Abstract: Nucleic oligomer probes useful for detection of HGBV in test samples. Also provided are assays which utilize these probes and test kits which contain these oligomer probes.

Abstract translation: 用于检测样品中HGBV的核寡聚体探针。 还提供了利用这些探针和包含这些寡聚体探针的测试试剂盒的测定法。

公开(公告)号：EP0845048A1

公开(公告)日：1998-06-03

申请号：EP96928178.0

申请日：1996-08-14

Applicant: ABBOTT LABORATORIES

Inventor： MARSHALL, Ronald, L. ,  JOU, Cynthia ,  SIMONS, John, N. ,  LEARY, Thomas, P. ,  MUERHOFF, A., Scott ,  DESAI, Suresh, M. ,  MUSHAHWAR, Isa, K.

IPC: C12N15 ,  C12Q1 ,  C12R1

CPC classification number: C12Q1/707 ,  C12Q1/686 ,  Y10S435/81

Abstract: Nucleic oligomer probes useful for detection of HGBV in test samples. Also provided are assays which utilize these probes and test kits which contain these oligomer probes.

公开(公告)号：EP0975804A2

公开(公告)日：2000-02-02

申请号：EP98915634.4

申请日：1998-04-17

Applicant: Abbott Laboratories

Inventor： JOU, Cynthia ,  MARSHALL, Ronald, L. ,  SCHEFFEL, Christi, P.

IPC: C12Q1/68

CPC classification number: C12Q1/6858

Abstract: Provided herein is an amplification based method for detecting mutant nucleic acid sequences.

公开(公告)号：EP0633944A1

公开(公告)日：1995-01-18

申请号：EP93908700.0

申请日：1993-03-31

Applicant: ABBOTT LABORATORIES

Inventor： BOUMA, Stanley, R. ,  GORDON, Julian ,  HOIJER, Joannel ,  JOU, Cynthia ,  RHOADS, James

IPC: C12N15 ,  C07K14 ,  C12M1 ,  C12Q1 ,  G01N33

CPC classification number: C12Q1/6813 ,  C07K14/4712 ,  C12N15/10 ,  C12Q1/6862 ,  C12Q1/6883 ,  C12Q2600/156 ,  C12Q2600/16 ,  G01N33/558

Abstract: The invention relates to multiplex ligase chain reaction (LCR). Two or more putative target sequences are selected. For each one, a set of four probes is used simultaneously to amplify the putative sequence if it is present in the sample. Preferably, all the amplicons are labeled with a common label/hapten and, for each different target, with a unique label/hapten. The invention also relates to an immunochromatographic strip device and method employing a diagonal array of capture spots.

公开(公告)号：EP0845048B1

公开(公告)日：2004-06-30

申请号：EP96928178.1

申请日：1996-08-14

Applicant: ABBOTT LABORATORIES

Inventor： MARSHALL, Ronald, L. ,  JOU, Cynthia ,  SIMONS, John, N. ,  LEARY, Thomas, P. ,  MUERHOFF, A., Scott ,  DESAI, Suresh, M. ,  MUSHAHWAR, Isa, K.

IPC: C12Q1/70 ,  C12Q1/68 ,  C07H21/04

CPC classification number: C12Q1/707 ,  C12Q1/686 ,  Y10S435/81

Abstract: Nucleic oligomer probes useful for detection of HGBV in test samples. Also provided are assays which utilize these probes and test kits which contain these oligomer probes.

公开(公告)号：EP0633944B1

公开(公告)日：2000-11-08

申请号：EP93908700.3

申请日：1993-03-31

Applicant: ABBOTT LABORATORIES

Inventor： BOUMA, Stanley, R. ,  GORDON, Julian ,  HOIJER, Joannel ,  JOU, Cynthia ,  RHOADS, James

IPC: C12P19/34 ,  G01N33/543

CPC classification number: C12Q1/6813 ,  C07K14/4712 ,  C12N15/10 ,  C12Q1/6862 ,  C12Q1/6883 ,  C12Q2600/156 ,  C12Q2600/16 ,  G01N33/558

Abstract: The invention relates to multiplex ligase chain reaction (LCR). Two or more putative target sequences are selected. For each one, a set of four probes is used simultaneously to amplify the putative sequence if it is present in the sample. Preferably, all the amplicons are labeled with a common label/hapten and, for each different target, with a unique label/hapten. The invention also relates to an immunochromatographic strip device and method employing a diagonal array of capture spots.