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公开(公告)号:EP0707482B1
公开(公告)日:1999-05-26
申请号:EP94923344.9
申请日:1994-07-06
Applicant: ABBOTT LABORATORIES
Inventor: EDWARDS, Carla , LARTEY, Paul A.
CPC classification number: C07H17/08
Abstract: Antibacterial compounds having formula (II) and pharmaceutically acceptable salts thereof, wherein Y is selected form (a), (b), and (c) and X is selected from the group consisting of -C(O)-, -C(S)-, CH2-, -CH2CH2- and -C(CH3)2-; also disclosed are processes and intermediates useful in the preparation of the above compounds, as well as compositions containing the same and methods for their use.
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公开(公告)号:EP0707482A1
公开(公告)日:1996-04-24
申请号:EP94923344.0
申请日:1994-07-06
Applicant: ABBOTT LABORATORIES
Inventor: EDWARDS, Carla , LARTEY, Paul A.
CPC classification number: C07H17/08
Abstract: Antibacterial compounds having formula (II) and pharmaceutically acceptable salts thereof, wherein Y is selected form (a), (b), and (c) and X is selected from the group consisting of -C(O)-, -C(S)-, CH2-, -CH2CH2- and -C(CH3)2-; also disclosed are processes and intermediates useful in the preparation of the above compounds, as well as compositions containing the same and methods for their use.
Abstract translation: 其中Y选自(a),(b)和(c)且X选自-C(O) - , - C(S) ) - ,CH 2 - , - CH 2 CH 2 - 和-C(CH 3)2 - ; 也公开了用于制备上述化合物的方法和中间体,以及含有它们的组合物及其使用方法。
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公开(公告)号:EP0623021B1
公开(公告)日:1998-04-08
申请号:EP93904533.2
申请日:1993-01-19
Applicant: ABBOTT LABORATORIES
Inventor: LARTEY, Paul A. , NELLANS, Hugh N. , KLEIN, Larry L. , FAGHIH, Ramin
CPC classification number: C07H17/08
Abstract: 4''-Deoxy derivatives of erythromycin having formula (I) and pharmaceutically acceptable salts thereof, which are enhancers of gastric motility but have minimal antibacterial activity, as well as pharmaceutical compositions containing the same and methods for their use and preparation.
Abstract translation: 4“ - 具有式(I)的红霉素的脱氧衍生物及其药学上可接受的盐,它们是胃运动增强剂但具有最小的抗菌活性,以及含有它们的药物组合物及其使用和制备方法。
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公开(公告)号:EP0623021A1
公开(公告)日:1994-11-09
申请号:EP93904533.0
申请日:1993-01-19
Applicant: ABBOTT LABORATORIES
Inventor: LARTEY, Paul A. , NELLANS, Hugh N. , KLEIN, Larry L. , FAGHIH, Ramin
CPC classification number: C07H17/08
Abstract: Dérivés 4''-désoxy d'érythromycine de formule (I) et leurs sels pharmaceutiquement acceptables, qui sont des stimulateurs de la motilité gastrique mais possèdent une activité antibactérienne minimale, ainsi que compositions pharmaceutiques les contenant et procédés pour leur utilisation et leur préparation.
Abstract translation: 衍生物4“” - 式(I)化合物及其药学上可接受的盐,其是胃肠蠕动的刺激剂,但具有最小的抗菌活性的红霉素脱氧,以及含有它们与它们的使用和制备方法的药物组合物。
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