公开(公告)号：EP0642516B1

公开(公告)日：2002-06-05

申请号：EP92920494.9

申请日：1992-09-08

Applicant: ABBOTT LABORATORIES

Inventor： LULY, Jay R. ,  KAWAI, Megumi ,  OR, Yat Sun ,  WIEDEMAN, Paul ,  WAGNER, Rolf

IPC: C07D498/18 ,  C07D498/04 ,  C07H19/01 ,  A61K31/395 ,  A61K31/33 ,  A61K31/70

CPC classification number: C07D487/14 ,  C07D513/14 ,  C07F7/1856 ,  C07F9/6561 ,  C07H19/01

Abstract: Immunomodulatory macrocylic compounds having the formula (VII) and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein X is selected from one of the formulae (Ia), (Ib) and (Ic), as well as pharmaceutical compositions containing the same.

公开(公告)号：EP0642516A1

公开(公告)日：1995-03-15

申请号：EP92920494.0

申请日：1992-09-08

Applicant: ABBOTT LABORATORIES

Inventor： LULY, Jay R. ,  KAWAI, Megumi ,  OR, Yat Sun ,  WIEDEMAN, Paul ,  WAGNER, Rolf

IPC: A61K31 ,  A61P1 ,  A61P17 ,  A61P21 ,  A61P29 ,  A61P37 ,  C07D487 ,  C07D491 ,  C07D498 ,  C07D513 ,  C07F7 ,  C07F9 ,  C07H19 ,  C12P17 ,  C12R1

CPC classification number: C07D487/14 ,  C07D513/14 ,  C07F7/1856 ,  C07F9/6561 ,  C07H19/01

Abstract: Immunomodulatory macrocylic compounds having the formula (VII) and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein X is selected from one of the formulae (Ia), (Ib) and (Ic), as well as pharmaceutical compositions containing the same.