公开(公告)号：WO2015094772A1

公开(公告)日：2015-06-25

申请号：PCT/US2014/069126

申请日：2014-12-08

Applicant: ABBOTT LABORATORIES

Inventor： MEADOR, Benjamin ,  PEREIRA, Suzette ,  EDENS, Neile ,  TISDALE, Michael

IPC: A23L1/30 ,  A23L1/29 ,  A61K31/353 ,  A61P21/00

CPC classification number: A61K31/353 ,  A23L33/105 ,  A23L33/115 ,  A23L33/125 ,  A23L33/17 ,  A23L33/30 ,  A23V2002/00 ,  A23V2200/316 ,  A23V2250/214 ,  A61K9/0053 ,  A61K31/19 ,  A61K36/82 ,  A61K45/06 ,  A61K2300/00

Abstract: Methods of increasing skeletal muscle protein synthesis in a subject are provided. Methods of increasing or maintaining mammalian target of rapamycin (mTOR) activation are also provided. Such methods include a step of administering at least one serving per day of a composition including 20 to 2,000 mg of a green tea extract per serving to the subject.

Abstract translation: 提供了在受试者中增加骨骼肌蛋白质合成的方法。 还提供了增加或维持哺乳动物雷帕霉素靶标（mTOR）活化的方法。 这样的方法包括每天给予至少一份服用组合物的步骤，其包含20至2,000mg每份一份绿茶提取物。

公开(公告)号：WO2015126716A1

公开(公告)日：2015-08-27

申请号：PCT/US2015/015566

申请日：2015-02-12

Applicant: ABBOTT LABORATORIES

Inventor： MEADOR, Benjamin ,  PEREIRA, Suzette ,  EDENS, Neile ,  PATEL, Gaurav

IPC: A23L1/30 ,  A23L1/305 ,  A23L2/52 ,  A23L2/66

CPC classification number: A23L2/52 ,  A23L2/66 ,  A23L33/10 ,  A23L33/105 ,  A23L33/17

Abstract: A liquid nutritional composition includes a source of epigallocatechin gallate and at least one of a source of protein, a source of carbohydrate, and a source of fat. The liquid nutritional composition includes gallocatechin gallate and epigallocatechin gallate in a ratio of about 1:20 to about 1:0.60. At least a portion of the gallocatechin gallate is formed by epimerization of the epigallocatechin gallate as a result of application of heat to the liquid nutritional composition. Methods of making the liquid nutritional composition are also provided.

Abstract translation: 液体营养组合物包括表没食子儿茶素没食子酸酯的来源和蛋白质来源，碳水化合物源和脂肪源中的至少一种。 液体营养组合物包含比例为约1:20至约1:0.60的没食子儿茶素没食子酸酯和表没食子儿茶素没食子酸酯。 通过向液体营养组合物施加热量，表儿茶素没食子酸酯的至少一部分由表没食子儿茶素没食子酸酯的差向异构化形成。 还提供了制备液体营养组合物的方法。

公开(公告)号：WO2015094767A1

公开(公告)日：2015-06-25

申请号：PCT/US2014/069092

申请日：2014-12-08

Applicant: ABBOTT LABORATORIES

Inventor： PEREIRA, Suzette ,  MEADOR, Benjamin ,  EDENS, Neile ,  PATEL, Gaurav

IPC: A23L1/30 ,  A61P3/00 ,  A61K31/353

CPC classification number: A61K31/353 ,  A23L33/105 ,  A61K35/20 ,  A61K36/28 ,  A61K36/82 ,  A61K36/889 ,  A61K36/899 ,  A61K38/018 ,  A61K2300/00

Abstract: Methods for maintaining or increasing bodyweight in a subject susceptible to unintentional weight loss are provided. The methods include a step of administering at least one serving per day of a composition including 20 to 2000 mg of a decaffeinated green tea extract per serving to the subject.

Abstract translation: 提供了在易受无意减肥的受试者中维持或增加体重的方法。 所述方法包括每天至少一次服用包含20至2000mg每份一次的脱咖啡因绿茶提取物的组合物的步骤。

公开(公告)号：EP3091859A1

公开(公告)日：2016-11-16

申请号：EP14821389.5

申请日：2014-12-08

Applicant: Abbott Laboratories

Inventor： MEADOR, Benjamin ,  PEREIRA, Suzette ,  EDENS, Neile ,  TISDALE, Michael

IPC: A23L33/00 ,  A23L33/10 ,  A61K31/353 ,  A61P21/00

CPC classification number: A61K31/353 ,  A23L33/105 ,  A23L33/115 ,  A23L33/125 ,  A23L33/17 ,  A23L33/30 ,  A23V2002/00 ,  A23V2200/316 ,  A23V2250/214 ,  A61K9/0053 ,  A61K31/19 ,  A61K36/82 ,  A61K45/06 ,  A61K2300/00

Abstract: Methods of increasing skeletal muscle protein synthesis in a subject are provided. Methods of increasing or maintaining mammalian target of rapamycin (mTOR) activation are also provided. Such methods include a step of administering at least one serving per day of a composition including 20 to 2,000 mg of a green tea extract per serving to the subject.