中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

13 records (took 0.032 seconds)

    REAGENTS AND METHODS USEFUL FOR DETECTING DISEASES OF THE BREAST
    1.
    发明申请
    REAGENTS AND METHODS USEFUL FOR DETECTING DISEASES OF THE BREAST 审中-公开
    用于检测乳腺疾病的试剂和方法

    公开(公告)号：WO1998007857A1

    公开(公告)日：1998-02-26

    申请号：PCT/US1997014665

    申请日：1997-08-19

    Applicant: ABBOTT LABORATORIES

    Inventor： ABBOTT LABORATORIES ,  BILLING-MEDEL, Patricia, A. ,  COHEN, Maurice ,  COLPITTS, Tracey, L. ,  FRIEDMAN, Paula, N. ,  GORDON, Julian ,  GRANADOS, Edward, N. ,  HODGES, Steven, C. ,  KLASS, Michael, R. ,  KRATOCHVIL, Jon, D. ,  ROBERTS-RAPP, Lisa ,  RUSSELL, John, C. ,  STROUPE, Steven, D.

    IPC: C12N15/12

    CPC classification number: C07K14/47 ,  C12Q1/6886 ,  C12Q2600/136

    Abstract: A novel member of the uteroglobin family of proteins, designated as BU101, is described. BU101 is defined by a set of contiguous and partially overlapping RNA sequences transcribed from breast tissue, and polypeptides encoded thereby. A fully sequenced clone representing the longest continuous sequence of BU101 is also disclosed. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the breast such as breast cancer. Also provided are antibodies which specifically bind to BU101-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific BU101 polypeptide, which molecules are useful for the therapeutic treatment of breast diseases, tumors or metastases.

    Abstract translation: 描述了称为BU101的蛋白质的子宫肌血清蛋白家族的新成员。 BU101由一组从乳腺组织转录的连续和部分重叠的RNA序列以及由此编码的多肽来定义。 还公开了表示BU101的最长连续序列的完全测序的克隆。 这些序列可用于检测，诊断，分期，监测，预后，预防或治疗或确定个体对乳腺疾病和状况（例如乳腺癌）的倾向。 还提供了特异性结合BU101编码的多肽或蛋白质的抗体，以及预防组织特异性BU101多肽的作用的激动剂或抑制剂，该分子可用于治疗乳腺疾病，肿瘤或转移瘤。

    REAGENTS AND METHODS USEFUL FOR DETECTING DISEASES OF THE PROSTATE
    4.
    发明申请
    REAGENTS AND METHODS USEFUL FOR DETECTING DISEASES OF THE PROSTATE 审中-公开
    用于检测前列腺疾病的试剂和方法

    公开(公告)号：WO1998015657A1

    公开(公告)日：1998-04-16

    申请号：PCT/US1997018290

    申请日：1997-10-08

    Applicant: ABBOTT LABORATORIES

    Inventor： ABBOTT LABORATORIES ,  COHEN, Maurice ,  FRIEDMAN, Paula, N. ,  GORDON, Julian ,  HODGES, Steven, C. ,  KLASS, Michael, R. ,  KRATOCHVIL, Jon, D. ,  ROBERTS-RAPP, Lisa ,  RUSSELL, John, C. ,  STROUPE, Steven, D.

    IPC: C12Q01/68

    CPC classification number: C07K14/82 ,  C07K14/47 ,  C12Q1/6886 ,  C12Q2600/136 ,  G01N33/57434

    Abstract: A set of contiguous and partially overlapping RNA sequences and polypeptides encoded thereby, designated as PS 112 and transcribed from prostate tissue is described. A fully sequenced clone representing a continuous sequence of PS 112 is also disclosed. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the prostate, such as prostate cancer. Also provided are antibodies which specifically bind to PS 112-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific PS 112 polypeptide, which molecules are useful for the therapeutic treatment of prostate diseases, tumours or metastases.

    Abstract translation: 描述了一组由其编码的连续和部分重叠的RNA序列和多肽，称为PS 112并从前列腺组织转录。 还公开了表示PS 112的连续序列的完全测序的克隆。 这些序列可用于检测，诊断，分期，监测，预后，预防或治疗或确定个体对前列腺疾病和状况（例如前列腺癌）的倾向。 还提供了特异性结合PS 112编码的多肽或蛋白质的抗体，以及预防组织特异性PS 112多肽的作用的激动剂或抑制剂，该分子可用于治疗前列腺疾病，肿瘤或转移瘤。

Patent Agency Ranking