公开(公告)号：WO2022245920A1

公开(公告)日：2022-11-24

申请号：PCT/US2022/029798

申请日：2022-05-18

Applicant: ABBOTT LABORATORIES

Inventor： MCQUISTON, Beth ,  DATWYLER, Saul ,  CHANDRAN, Raj ,  ZHANG, Hongwei ,  MARINO, Jaime

IPC: G01N33/68 ,  G01N2800/28 ,  G01N33/6896

Abstract: Disclosed herein are methods, and kits for use in said methods, that aid in the diagnosis and evaluation of a pediatric subject for traumatic brain injury (TBI), using ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), glial fibrillary acidic protein (GFAP), or a combination thereof. Also disclosed herein are methods, and kits for use in said methods, that aid in determining whether a pediatric subject would benefit from and thus receive an imaging procedure, such as MRI or head computerized tomography (CT) scan based on the levels of GFAP, UCH-L1 or GFAP and UCH-L1.

公开(公告)号：EP4396587A1

公开(公告)日：2024-07-10

申请号：EP22777531.9

申请日：2022-08-30

Applicant: Abbott Laboratories

Inventor： ZHANG, Hongwei ,  MCQUISTON, Beth ,  DATWYLER, Saul ,  CHANDRAN, Raj

IPC: G01N33/68

CPC classification number: G01N33/6896 ,  G01N33/6893 ,  G01N2800/287120130101 ,  G01N2800/2820130101

公开(公告)号：EP4341699A1

公开(公告)日：2024-03-27

申请号：EP22728744.8

申请日：2022-05-18

Applicant: Abbott Laboratories

Inventor： MCQUISTON, Beth ,  DATWYLER, Saul ,  CHANDRAN, Raj ,  ZHANG, Hongwei ,  MARINO, Jaime

IPC: G01N33/68

公开(公告)号：EP4441509A1

公开(公告)日：2024-10-09

申请号：EP22840849.8

申请日：2022-11-29

Applicant: Abbott Laboratories

Inventor： MCQUISTON, Beth ,  DATWYLER, Saul ,  CHANDRAN, Raj ,  MARINO, Jaime ,  ZHANG, Hongwei

IPC: G01N33/68

CPC classification number: G01N33/6896 ,  G01N2333/94820130101

公开(公告)号：EP4256348A1

公开(公告)日：2023-10-11

申请号：EP21831406.0

申请日：2021-11-30

Applicant: Abbott Laboratories

Inventor： MCQUISTON, Beth ,  DATWYLER, Saul ,  CHANDRAN, Raj ,  MARINO, Jaime ,  ZHANG, Hongwei

IPC: G01N33/68