Novel glycan conjugates and use thereof

    公开(公告)号:AU2015305332A1

    公开(公告)日:2017-03-09

    申请号:AU2015305332

    申请日:2015-08-21

    Abstract: This disclosure includes an immunogenic composition containing (a) a glycan conjugate including a carrier and one or more glycans, wherein each of the one or more glycans is conjugated with the carrier through a linker, and optionally (b) an adjuvant. The one or more glycan is each a Globo H derivative.

    Conjugados de glicanos y uso de los mismos

    公开(公告)号:ES2820303T3

    公开(公告)日:2021-04-20

    申请号:ES15833684

    申请日:2015-08-21

    Abstract: Una composición inmunogénica que comprende: (a) un conjugado de glicanos que comprende por lo menos un glicano con un conector y un portador, el por lo menos un glicano estando conjugado con el portador a través del conector; y (b) un adyuvante, en donde el por lo menos un glicano con el conector tiene una estructura química de fórmula (II): **(Ver fórmula)** en donde: R1 se selecciona del grupo que consiste de -F, -N3, -NO2, **(Ver fórmula)** y R2 es -CH3; o R1 es -OH, y R2 se selecciona del grupo que consiste de -CH2F, -CH2N3, -CH2OH y -C≡CH.

    Novel glycan conjugates and use thereof

    公开(公告)号:NZ729243A

    公开(公告)日:2018-08-31

    申请号:NZ72924315

    申请日:2015-08-21

    Abstract: This disclosure relates to an immunogenic composition comprising (a) a glycan conjugate comprising at least one glycan with a link and a carrier wherein the or each glycan is conjugated to the carrier through the linker, and (b) optionally an adjuvant. The or each glycan with the linker has a chemical structure of formula (II) wherein R1 is selected from the group consisting of –F, -N3, -NO2, and ORA where RA is an optionally substituted aryl, and R2 is –CH3; or R1 is –OH, and R2 is selected from the group consisting of –CH2F, -CH2N3, -CH2OH, and –C=CH.

    Novel glycan conjugates and use thereof

    公开(公告)号:AU2015305332B2

    公开(公告)日:2018-04-12

    申请号:AU2015305332

    申请日:2015-08-21

    Abstract: This disclosure includes an immunogenic composition containing (a) a glycan conjugate including a carrier and one or more glycans, wherein each of the one or more glycans is conjugated with the carrier through a linker, and optionally (b) an adjuvant. The one or more glycan is each a Globo H derivative.

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