AZO-QUATERNARY PYRIDINIUM SALTS WITH ACID-ENHANCED ANTIBACTERIAL EFFICACY, METHODS OF USE, METHODS OF SYNTHESES, AND USES THEREOF
    3.
    发明申请
    AZO-QUATERNARY PYRIDINIUM SALTS WITH ACID-ENHANCED ANTIBACTERIAL EFFICACY, METHODS OF USE, METHODS OF SYNTHESES, AND USES THEREOF 审中-公开
    AZO-QUATERNARY PYRIDINIUM盐与酸增强的抗菌功效,使用方法,合成方法及其用途

    公开(公告)号:WO2018071262A1

    公开(公告)日:2018-04-19

    申请号:PCT/US2017/055283

    申请日:2017-10-05

    Inventor: SUN, Jirun

    Abstract: A new azo-type quaternary pyridinium salt (Azo-QPS) shows enhanced activity at acidic conditions (e.g., pH = 5); in neutral or basic conditions, this new Azo-QPS shows a much lower level (2 - 50 times lower) anti-bacterial activity. The use of such a "stimulus- enhance" antibiotic can response to the proliferation of bacteria directly. It helps reduce or prevent the build-up of potent antibacterial agents in the oral environment. The antibacterial properties of Azo-QPS are "activated" when the environmental pH becomes acidic; this acidic pH may be indicative of the accumulation of Streptococcus mutans , or the initiation of tooth decay.

    Abstract translation: 新的偶氮型季吡啶鎓盐(Azo-QPS)在酸性条件下(例如,pH = 5)显示增强的活性; 在中性或碱性条件下,这种新的偶氮-QPS显示出低得多的水平(2-50倍)的抗菌活性。 使用这种“刺激 - 增强” 抗生素可以直接响应细菌的增殖。 它有助于减少或防止在口腔环境中积聚有效的抗菌剂。 偶氮-QPS的抗菌性能被“活化” 当环境pH值变为酸性时; 该酸性pH值可能表明变形链球菌的积聚或蛀牙的发生。

    RAPID AZEOTROPIC PHOTO-COPOLYMERIZATION OF STYRENE AND METHACRYLATE DERIVATIVES AND USES THEREOF
    4.
    发明申请
    RAPID AZEOTROPIC PHOTO-COPOLYMERIZATION OF STYRENE AND METHACRYLATE DERIVATIVES AND USES THEREOF 审中-公开
    苯乙烯和甲基丙烯酸酯衍生物的快速拉伸光聚合及其用途

    公开(公告)号:WO2017058852A1

    公开(公告)日:2017-04-06

    申请号:PCT/US2016/054079

    申请日:2016-09-28

    Inventor: SUN, Jirun

    Abstract: A composition of matter includes a mixture of styrene derivative monomers and methacrylate/acrylate derivative monomers, which have one or more urethane, carbamate, amide, and/or amine functional groups, and initiators, and the compositions are used to achieve composition control of the forming polymer, with the mole fraction of acrylate/methacrylate and styrene moieties in the forming polymer determined preferably by the chemistry and composition of the feeding monomers rather than the viscosity of the monomers.

    Abstract translation: 物质组合物包括具有一个或多个氨基甲酸酯,氨基甲酸酯,酰胺和/或胺官能团的苯乙烯衍生物单体和甲基丙烯酸酯/丙烯酸酯衍生物单体的混合物和引发剂,并且组合物用于实现 形成聚合物,其中成型聚合物中丙烯酸酯/甲基丙烯酸酯和苯乙烯部分的摩尔分数优选通过进料单体的化学和组成而不是单体的粘度来确定。

    3D PRINTING OF COMPOSITION-CONTROLLED COPOLYMERS
    5.
    发明申请
    3D PRINTING OF COMPOSITION-CONTROLLED COPOLYMERS 审中-公开
    3D成分控制的共聚物的印刷

    公开(公告)号:WO2018063816A1

    公开(公告)日:2018-04-05

    申请号:PCT/US2017/051584

    申请日:2017-09-14

    Abstract: A computer-controiied method for forming a composition-controlled product using 3D printing includes disposing two or more liquid reactant compositions in respective two or more reservoirs; and mixing the two or more liquid reactant compositions, which in turn includes controlling by the computer a mass ratio of the mixed two or more liquid reactant compositions. The computer-controlled method further inciudes scanning, under control of the computer, a mixed liquid reactants nozzle over a substrate; depositing the mixed liquid reactant compositions onto the substrate; and operating, under control of the computer, a light source to polymerize the deposited mixed liquid reactant compositions.

    Abstract translation: 计算机控制的使用3D打印形成组合物控制产品的方法包括将两种或更多种液体反应物组合物设置在相应的两个或更多个储存器中; 以及混合两种或更多种液体反应物组合物,其又包括通过计算机控制混合的两种或更多种液体反应物组合物的质量比。 计算机控制的方法还包括在计算机的控制下,在衬底上扫描混合液体反应物喷嘴; 将混合液体反应物组合物沉积到基底上; 并在计算机控制下操作光源以聚合沉积的混合液体反应物组合物。

    ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS
    6.
    发明申请
    ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS 审中-公开
    环保和水性稳定树脂,树脂单体和树脂复合材料用于牙科应用

    公开(公告)号:WO2016160299A1

    公开(公告)日:2016-10-06

    申请号:PCT/US2016/021686

    申请日:2016-03-10

    Applicant: ADA FOUNDATION

    CPC classification number: A61K6/083 A61K6/0835 C08L33/08

    Abstract: A composition of matter includes one or more functionalized vinylbenzyl components of the formula covalently connected to one or more R functional components; the one or more R functional groups selected from a group including one or more hydroxyl methyl (-CHOH-) moieties and/or derivatives thereof, one or more ethoxy (-CH2-CH2-O-) moieties and/or derivatives thereof, and one or more benzene (C6H6) and/or derivatives thereof; and ether links that connect the functionalized vinylbenzyl components and the R functional components.

    Abstract translation: 物质组合物包括共价连接到一个或多个R官能组分的一种或多种下式的官能化乙烯基苄基组分; 一个或多个选自包括一个或多个羟基甲基(-CHOH-)部分和/或其衍生物,一个或多个乙氧基(-CH 2 -CH 2 -O-)部分和/或其衍生物的基团的R官能团,以及 一种或多种苯(C 6 H 6)和/或其衍生物; 和连接官能化乙烯基苄基组分和R官能组分的醚连接。

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