公开(公告)号：JPS63267438A

公开(公告)日：1988-11-04

申请号：JP10278687

申请日：1987-04-24

Applicant: AGENCY IND SCIENCE TECHN

Inventor： TOBA MAKOTO ,  MIZUKAMI FUJIO ,  NIWA SHUICHI ,  SHIMIZU KAZUO ,  IMAI SUMI

IPC: B01J23/20 ,  C01B33/12 ,  C07B61/00 ,  C07C27/00 ,  C07C29/04 ,  C07C35/08 ,  C07C67/00

Abstract: PURPOSE:To control the function of pores and enhance the separation identification capability by adding water to a mixture of niobium alkoxide, silicon alkoxide and alcohol to obtain gelation and thereby forming an amorphous niobium oxide silica catalyst. CONSTITUTION:Niobium alkoxide and silicon alkoxide which are raw materials for niobium oxide and silica, and alcohol are mixed for a fixed duration, and water is added to obtain gelation. After this, the gel is dried to manufacture an amorphous niobium oxide-silica catalyst. The preferable mixing ratio of niobium and silicon is 2-100 at the atomic ratio of Si/Nb=0.5-200. In order to insure smooth mixing or gelation, alcohols are employed, and also an additive is formulated if necessary. The preferable dosage of alcohols is 1-5mol. to mol. of silicon alkoxide. The recommendable additives are 1,2-diketone, 1,3- diketone, alpha-ketone, etc.

公开(公告)号：JPS6327502A

公开(公告)日：1988-02-05

申请号：JP17215586

申请日：1986-07-22

Applicant: AGENCY IND SCIENCE TECHN

Inventor： MIZUKAMI FUJIO ,  TOBA MAKOTO ,  NIWA SHUICHI ,  IMAI SUMI

IPC: A61K9/26 ,  C01B33/113 ,  C07B63/02 ,  C08B37/16 ,  C08L5/16 ,  C12N11/14

Abstract: PURPOSE:To obtain a thermally and chemically stable novel composite material, by blending an alkoxysilane with a cyclodextrin, adding water to the blend and gelatinizing so that the cyclodextrin is taken in amorphous silane. CONSTITUTION:An alkoxysilane (e.g. tetramethoxysilane, tetrabutoxysilane, etc.) is blended with a cyclodextrin (e.g. beta,gamma,delta-cyclodextrin single substance, etc.) usually in the amount of

公开(公告)号：JPS63130142A

公开(公告)日：1988-06-02

申请号：JP27717686

申请日：1986-11-20

Applicant: AGENCY IND SCIENCE TECHN

Inventor： TOBA MAKOTO ,  MIZUKAMI FUJIO ,  NIWA SHUICHI ,  IMAI SUMI

IPC: B01J27/02 ,  B01J27/053 ,  C07B61/00 ,  C07C1/00 ,  C07C2/66 ,  C07C2/70 ,  C07C2/86 ,  C07C15/24 ,  C07C67/00

Abstract: PURPOSE:To selectively prepare alkylnaphthalene, by mixing metal alkoxides with sulfuric ester and alcohol and adding water to the resulting mixture to gel the same to contain sulfuric acid in amorphous silica-alumina. CONSTITUTION:Metal alkoxides becoming a raw material of silica and alumina are mixed with alcohol and sulfuric ester for a definite time in a solution, and water is added to the resulting mixture to gel the same while the obtained gel is dried to prepare a sulfuric acid-containing silica-alumina catalyst wherein sulfuric acid is contained in silica-alumina. As sulfuric acid ester, dimethyl sulfate and diethyl sulfate are pref. because easy to obtain and the content of sulfuric acid is pref. 3-12wt%. As the silica raw material, lower alkoxysilane is pref. and, as the alumina raw material, aluminum methoxide is pref. By using this catalyst, the acetylation of naphthalene smoothly advances in a position selective manner.

公开(公告)号：JPS6369540A

公开(公告)日：1988-03-29

申请号：JP21333786

申请日：1986-09-10

Applicant: AGENCY IND SCIENCE TECHN

Inventor： MIZUKAMI FUJIO ,  NIWA SHUICHI ,  TOBA MAKOTO ,  IMAI SUMI

IPC: B01J20/22 ,  B01J20/281 ,  B01J20/283 ,  C07F7/02 ,  C07H23/00 ,  C08G77/14 ,  C08G77/22 ,  G01N30/88

Abstract: PURPOSE:To obtain the title sugar alcohol-silica composite made highly functional, by mixing alkoxysilanes and sugar alcohols, adding water to gel the mixture, and occluding the sugar alcohols in the amorphous silica. CONSTITUTION:Sugar alcohols (e.g., inositol) and alkoxysilanes (e.g., tetraethoxysilane) are mixed along with a solvent and a reaction accelerator, as required. From 2-30mol water is the preferably added to 1mol of the alkoxysilane to gel the mixture. The gelled material is dried at 50-100 deg.C under reduced pressure to obtain a sugar alcohol-silica composite. The obtained composite has excellent heat stability and chemical stability, and is insoluble in water. As a result, the composite can be excellently used as an adsorption and separation agent having a molecule identifying function with high selectivity, a highly functional chromatography packing agent having a long service life, and a separating and dividing agent for geometrical optical isomers.

公开(公告)号：JPS6363696A

公开(公告)日：1988-03-22

申请号：JP20759586

申请日：1986-09-03

Applicant: AGENCY IND SCIENCE TECHN

Inventor： MIZUKAMI FUJIO ,  NIWA SHUICHI ,  TOBA MAKOTO ,  IMAI SUMI

IPC: B01J20/22 ,  B01J20/281 ,  C01B33/12 ,  C01B33/152 ,  C07H23/00

Abstract: NEW MATERIAL:A saccharide-silica complex obtained by introducing a saccharide into amorphous silica. USE:Is useful as an adsorbent, separating agent, agent for optical resolution, packaging agent for thin-layer chromatography or gel chromatography, has more improved heat stability than a saccharide itself, is water-insoluble and readily produced. PREPARATION:An alkoxysilane (e.g. tetramethoxysilane, etc.) is blended with a saccharide (e.g. glucose, etc.) and water optionally in the presence of both a solvent (e.g. isopropanol, etc.) and a reaction promoter (e.g. acetic acid) preferably at 40-80 deg.C and gelatinized. The amount of the saccharide is preferably