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Patent Agency Ranking1.发明申请COMBINATION OF QUINOLONE ANTIBIOTICS AND STEROIDS FOR TOPICAL OPHTHALMIC USE 审中-公开Quinolone抗生素和STEROIDS组合用于局部OPHTHALMIC使用
公开(公告)号：WO1990001933A1
公开(公告)日：1990-03-08
申请号：PCT/US1989003648
申请日：1989-08-24
Applicant: ALCON LABORATORIES, INC.
Inventor： ALCON LABORATORIES, INC. , CAGLE, Gerald, D.
IPC: A61K31/56
CPC classification number: A61K9/0048 , A61K31/57 , A61K31/495 , A61K2300/00
Abstract: Disclosed are pharmaceutical compositions containing a quinolone antibiotic, such as ciprofloxacin, and a steroid, such as rimexolone, dexamethasone, fluorometholone or fluorometholone acetate, and the like for topical ophthalmic delivery, and a method of treatment comprising administering said compositions topically to the affected ocular tissue when indicated for control of infection and associated inflammation.
Abstract translation: 本发明公开了含有喹诺酮类抗生素（如环丙沙星）和类固醇（如雷米洛尔，地塞米松，氟孕酮或醋酸氟米隆）等用于局部眼科输送的药物组合物，以及治疗方法，包括将所述组合物局部施用于受影响的眼部 指示用于控制感染和相关炎症时的组织。
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2.发明申请
公开(公告)号：WO1989009057A1
公开(公告)日：1989-10-05
申请号：PCT/US1989000952
申请日：1989-03-09
Applicant: ALCON LABORATORIES, INC.
Inventor： ALCON LABORATORIES, INC. , CAGLE, Gerald, D. , MCDONALD, Thomas, O. , ROSENTHAL, Allan, L.
IPC: A61K31/74
CPC classification number: A61K31/70 , A61K31/57 , A61K2300/00
Abstract: Disclosed are pharmaceutical compositions comprising tobramycin and a steroid such as dexamethasone or fluorometholone for topical ophthalmic delivery and a method of treatment comprising administering said composition when indicated for infection and control of inflammatory response for optimal wound healing and normalization of the eye of a human or animal.
Abstract translation: 公开了包含妥布霉素和类固醇例如地塞米松或氟替米隆用于局部眼科递送的药物组合物，以及一种治疗方法，包括当指示感染时施用所述组合物，并控制炎症反应以获得最佳伤口愈合和人或动物眼睛的归一化 。
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3.发明申请IMPROVED INTRAOCULAR IRRIGATING SOLUTION CONTAINING NON-STEROIDAL ANTIINFLAMMATORY AGENT 审中-公开含有非甾体抗炎药物的改善的室内灌注溶液
公开(公告)号：WO1995016435A2
公开(公告)日：1995-06-22
申请号：PCT/US1994014196
申请日：1994-12-13
Applicant: ALCON LABORATORIES, INC.
Inventor： ALCON LABORATORIES, INC. , CAGLE, Gerald, D. , LORENZETTI, Ole, J. , GAN, Owen
IPC: A61K09/08
CPC classification number: A61K9/0048
Abstract: Pharmaceutical compositions useful in ophthalmic surgery are described. The compositions include one or more non-steroidal antiinflammatory drugs, and are useful for preventing or treating ophthalmic inflammation and other conditions associated with ophthalmic surgery. Methods of using the compositions in connection with ophthalmic surgical procedures are also described.
Abstract translation: 描述了可用于眼科手术的药物组合物。 组合物包括一种或多种非甾体抗炎药，并且可用于预防或治疗眼科炎症和与眼科手术相关的其它病症。 还描述了使用组合物与眼科外科手术相关的方法。
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公开(公告)号：EP0365613A1
公开(公告)日：1990-05-02
申请号：EP89903311.0
申请日：1989-03-09
Applicant: ALCON LABORATORIES, INC.
Inventor： CAGLE, Gerald, D. , MCDONALD, Thomas, O. , ROSENTHAL, Allan, L.
CPC classification number: A61K31/70 , A61K31/57 , A61K2300/00
Abstract: On a mis au point des préparations pharmaceutiques comprenant de la tobramycine ainsi qu'un stéroide tel que la dexaméthasone ou le fluorométholone destinés à une administration ophtalmique topique. On a prévu un procédé de traitement consistant à administrer ladite préparation lorsqu'elle est indiquée pour une infection et la régulation d'une réaction inflammatoire, afin d'obtenir une guérison optimale de la lésion et le retour à l'état normal de l'oeil chez l'homme ou l'animal.
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公开(公告)号：EP0365613B1
公开(公告)日：1995-05-17
申请号：EP89903311.2
申请日：1989-03-09
Applicant: ALCON LABORATORIES, INC.
Inventor： CAGLE, Gerald, D. , MCDONALD, Thomas, O. , ROSENTHAL, Allan, L.
CPC classification number: A61K31/70 , A61K31/57 , A61K2300/00
Abstract: Disclosed are pharmaceutical compositions comprising tobramycin and a steroid such as dexamethasone or fluorometholone for topical ophthalmic delivery and a method of treatment comprising administering said composition when indicated for infection and control of inflammatory response for optimal wound healing and normalization of the eye of a human or animal.
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