公开(公告)号：EP1054633A1

公开(公告)日：2000-11-29

申请号：EP99904565.1

申请日：1999-02-03

Applicant: ANGIOSONICS INC.

Inventor： ROSENSCHEIN, Uri ,  ROZESZJAN, Arie

IPC: A61B17/22

CPC classification number: A61B17/22012 ,  A61B2017/22008 ,  A61B2017/22082 ,  A61B2017/22088 ,  A61M37/0092

Abstract: A system and method for inhibiting restenosis by compromising the migration, viability and adhesion of mammalian smooth muscle cells (SMC). The system includes an ultrasonic energy source; a transmitter for transmitting the ultrasonic energy to the SMC and a drug delivery spectrum for delivering drugs to the smooth mucles cells. This system and method is especially useful in the prevention of restenosis in a blood vessel of a mammal associated with the migration of SMC in the blood vessel following vascular intervention, such as angioplasty.