公开(公告)号：EP1141338A4

公开(公告)日：2002-09-25

申请号：EP98966139

申请日：1998-12-31

Applicant: ARCH DEV CORP

Inventor： WHITLEY RICHARD J ,  ROIZMAN BERNARD

IPC: C12N15/09 ,  A61K35/76 ,  A61K38/00 ,  A61K38/20 ,  A61K48/00 ,  A61P35/00 ,  C12N7/00 ,  C12N15/869 ,  C12R1/93 ,  C12N15/63 ,  C12N15/86

CPC classification number: C12N7/00 ,  A61K35/763 ,  A61K38/00 ,  A61K48/00 ,  C07K14/5406 ,  C07K14/5428 ,  C12N15/86 ,  C12N2710/16632 ,  C12N2710/16643

Abstract: Recombinant herpes simplex viruses comprising DNA encoding cytokines and methods for treating neoplastic diseases using the inventive recombinant viruses are disclosed.

公开(公告)号：CA2356937A1

公开(公告)日：2000-07-13

申请号：CA2356937

申请日：1998-12-31

Applicant: ARCH DEV CORP

Inventor： ROIZMAN BERNARD ,  WHITLEY RICHARD J

IPC: C12N15/09 ,  A61K35/76 ,  A61K35/763 ,  A61K38/00 ,  A61K38/20 ,  A61K48/00 ,  A61P35/00 ,  C12N7/00 ,  C12N15/869 ,  C12R1/93 ,  C12N15/63

Abstract: Recombinant herpes simplex viruses comprising DNA encoding cytokines and methods for treating neoplastic diseases using the inventive recombinant viruses are disclosed.