公开(公告)号：BR0308878A

公开(公告)日：2005-01-04

申请号：BR0308878

申请日：2003-04-01

Applicant: ASPECT MEDICAL SYSTEMS INC

Inventor： DAHAN ALBERT ,  GREENWALD SCOTT D

IPC: A61B5/024 ,  A61B5/0285 ,  A61B5/11 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/16 ,  A61B5/352 ,  A61B5/366 ,  A61M5/00 ,  A61M16/01 ,  A61M21/02

Abstract: A PTT monitoring system for measuring arousal and responses to stress or pain during sedation or anesthesia. includes ECG electrodes and a PPG probe connected to a computer via signal conditioning and digitizing hardware. Lead I is typically used as the ECG lead while the PPG probe is typically placed on a finger. The ECG and PPG waveforms are continuously analyzed to update and display a current estimate of the subject's PPT from heart to hand. For each cardiac cycle, fiducial points are identified to indicate the pulse onset time (via QRS detection in the ECG) and pulse arrival time (via the point of steepest ascent in the PPG). The onset and arrival times for each cardiac cycle are paired, and the time difference is the interval estimate for that beat. An artifact post-processor (e.g., trim-mean filtering) excludes unlikely intervals from entering the averaged, current estimate of PTT. Finally, the current PTT estimate is displayed numerically and the trend of PTT is updated every second. Clinicians may interpret the instantaneous PTT value directly or in context of its recent trend. If there is a rapid decrease in PTT much less than the predetermined baseline value when the patient should be unconscious and free of stress and pain, then supplemental analgesics are administered to bring PTT greater than or equal to such baseline value.

公开(公告)号：CA2479916C

公开(公告)日：2013-10-29

申请号：CA2479916

申请日：2003-04-01

Applicant: ASPECT MEDICAL SYSTEMS INC

Inventor： DAHAN ALBERT ,  GREENWALD SCOTT D

IPC: A61B5/0285 ,  A61B5/024 ,  A61B5/11 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/16 ,  A61B5/352 ,  A61B5/366 ,  A61M5/00 ,  A61M16/01 ,  A61M21/02

Abstract: A PTT (Pulse Transit Time) monitoring system for measuring arousal and responses to stress or pain during sedation or anesthesia includes ECG electrodes and a PPG (photo plethysmography) probe connected to a computer via signal conditioning and digitizing hardware. The ECG and PPG waveforms are continuously analyzed to update and display a current estimate of the subject's PPT from heart to hand. For each cardiac cycle, fiducial points are identified to indicate the pulse onset time (via QRS detection in the ECG) and pulse arrival time (via the point of steepest ascent in the PPG). Finally, the current PTT estimate is displayed numerically and the trend of PTT is updated every second. Clinicians may interpret the instantaneous PTT value directly or in context of its recent trend. If there is a rapid decrease in PTT much less than the predetermined baseline value when the patient should be unconscious and free of stress and pain, then supplemental analgesics are administered to bring PTT greater than or equal to such baseline value.

公开(公告)号：AU2003226171A1

公开(公告)日：2003-10-20

申请号：AU2003226171

申请日：2003-04-01

Applicant: ASPECT MEDICAL SYSTEMS INC

Inventor： DAHAN ALBERT ,  GREENWALD SCOTT D

IPC: A61B5/024 ,  A61B5/0285 ,  A61B5/11 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/16 ,  A61B5/352 ,  A61B5/366 ,  A61M5/00 ,  A61M16/01 ,  A61M21/02

Abstract: A PTT monitoring system for measuring arousal and responses to stress or pain during sedation or anesthesia. includes ECG electrodes and a PPG probe connected to a computer via signal conditioning and digitizing hardware. Lead I is typically used as the ECG lead while the PPG probe is typically placed on a finger. The ECG and PPG waveforms are continuously analyzed to update and display a current estimate of the subject's PPT from heart to hand. For each cardiac cycle, fiducial points are identified to indicate the pulse onset time (via QRS detection in the ECG) and pulse arrival time (via the point of steepest ascent in the PPG). The onset and arrival times for each cardiac cycle are paired, and the time difference is the interval estimate for that beat. An artifact post-processor (e.g., trim-mean filtering) excludes unlikely intervals from entering the averaged, current estimate of PTT. Finally, the current PTT estimate is displayed numerically and the trend of PTT is updated every second. Clinicians may interpret the instantaneous PTT value directly or in context of its recent trend. If there is a rapid decrease in PTT much less than the predetermined baseline value when the patient should be unconscious and free of stress and pain, then supplemental analgesics are administered to bring PTT greater than or equal to such baseline value.

公开(公告)号：CA2479916A1

公开(公告)日：2003-10-16

申请号：CA2479916

申请日：2003-04-01

Applicant: ASPECT MEDICAL SYSTEMS INC

Inventor： DAHAN ALBERT ,  GREENWALD SCOTT D

IPC: A61B5/024 ,  A61B5/0285 ,  A61B5/11 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/16 ,  A61B5/352 ,  A61B5/366 ,  A61M5/00 ,  A61M16/01 ,  A61M21/02

Abstract: A PTT (Pulse Transit Time) monitoring system for measuring arousal and responses to stress or pain during sedation or anesthesia includes ECG electrodes and a PPG (photo plethysmography) probe connected to a computer v ia signal conditioning and digitizing hardware. The ECG and PPG waveforms are continuously analyzed to update and display a current estimate of the subject's PPT from heart to hand. For each cardiac cycle, fiducial points ar e identified to indicate the pulse onset time (via QRS detection in the ECG) a nd pulse arrival time (via the point of steepest ascent in the PPG). Finally, t he current PTT estimate is displayed numerically and the trend of PTT is update d every second. Clinicians may interpret the instantaneous PTT value directly or in context of its recent trend. If there is a rapid decrease in PTT much les s than the predetermined baseline value when the patient should be unconscious and free of stress and pain, then supplemental analgesics are administered t o bring PTT greater than or equal to such baseline value.