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    SYSTEM AND METHOD OF ASSESSING ANALGESIC ADEQUACY USING BIOPOTENTAL VARIABILITY
    2.
    发明申请
    SYSTEM AND METHOD OF ASSESSING ANALGESIC ADEQUACY USING BIOPOTENTAL VARIABILITY 审中-公开
    使用生物多样性变量评估厌氧成分的系统和方法

    公开(公告)号：WO2007115215A3

    公开(公告)日：2008-04-24

    申请号：PCT/US2007065708

    申请日：2007-03-30

    Applicant: ASPECT MEDICAL SYSTEMS INC ,  GREENWALD SCOTT D

    Inventor： GREENWALD SCOTT D

    IPC: A61B5/05 ,  A61B5/00

    CPC classification number: A61B5/04012 ,  A61B5/048 ,  A61B5/0488 ,  A61B5/4821

    Abstract: The system and method for predicting and measuring a subject's analgesic state and analgesic adequacy. Biopotential signals are obtained from a subject through electrodes. A processor will compute a measure that is representative of the subject's sedative state and/or muscle activity. A metric representative of such measures is then determined. In the case where a measure is taken of both the subjects' sedative state and muscle activity the two measures are combined into an index representative of the subject's analgesic state and analgesic adequacy.

    Abstract translation: 用于预测和测量受试者止痛状态和止痛充足性的系统和方法。 通过电极从受试者获得生物电位信号。 处理器将计算代表受试者的镇静状态和/或肌肉活动的度量。 然后确定此类措施的度量标准。 在对受试者的镇静状态和肌肉活动进行测量的情况下，将两种措施组合成代表受试者的止痛状态和止痛充足性的指标。

    SYSTEM AND METHOD FOR EEG IMAGING OF CEREBRAL ACTIVITY USING ELECTRODE SETS
    3.
    发明申请
    SYSTEM AND METHOD FOR EEG IMAGING OF CEREBRAL ACTIVITY USING ELECTRODE SETS 审中-公开
    使用电极组进行脑电图成像的系统和方法

    公开(公告)号：WO2006060727A9

    公开(公告)日：2007-04-05

    申请号：PCT/US2005043777

    申请日：2005-12-05

    Applicant: ASPECT MEDICAL SYSTEMS INC ,  KOFOL TIM ,  GREENWALD SCOTT D ,  DEVLIN PHILIP H

    Inventor： KOFOL TIM ,  GREENWALD SCOTT D ,  DEVLIN PHILIP H

    IPC: A61B5/05

    CPC classification number: A61B5/0476

    Abstract: The invention provides a method of estimating cerebral sources of electrical activity from a small subset of EEG channels utilizing existing methods to provide a 3­dimensional, discrete, distributed, linear solution to the inverse problem using inputs consisting of a small number of EEG channels (e.g., 4 channels) augmented with synthetic EEG data for the other channels. The resultant image of cerebral electrical activity in the region of the EEG channels from which data is recorded is of comparable spatial resolution in the corresponding region to images of cerebral electrical activity obtained using a complete set of EEG channels (e.g., using 24 channels).

    Abstract translation: 本发明提供了一种使用现有方法从EEG信道的一小部分估计电活动的脑源的方法，以使用由少数EEG信道（例如，多个）组成的输入向反问题提供三维，离散，分布，线性解。 ，4个通道）增加了其他通道的合成脑电图数据。 在其中记录数据的EEG信道区域中的脑电活动的所得图像在相应区域中与使用完整的一组EEG信道（例如，使用24个信道）获得的脑电活动的图像具有可比较的空间分辨率。

    5.
    发明专利
    未知

    公开(公告)号：BR0306712A

    公开(公告)日：2004-12-28

    申请号：BR0306712

    申请日：2003-01-06

    Applicant: ASPECT MEDICAL SYSTEMS INC

    Inventor： GREENWALD SCOTT D ,  SMITH CHARLES P ,  SIGL JEFFREY C ,  DEVLIN PHILIP H

    IPC: A61B5/16 ,  A61B5/374 ,  G06K9/00 ,  A61B5/00

    Abstract: The present invention is a system and method that produces features and indices that indicate the presence or absence of a disease or condition, or of the progression of a disease or condition. The system and method of the present invention also produce features and indices that predict responsiveness to medication from a premedication baseline. The system and method of the present invention further incorporates a testing methodology to improve the performance characteristics of the features or indices. To obtain such features and indices, time domain, power spectrum, bispectrum and higher order spectrum values are derived from biopotential signals taken from the subject being tested.

    SYSTEM AND METHOD FOR ENHANCING AND SEPARATING BIOPOTENTIAL SIGNALS
    7.
    发明专利
    SYSTEM AND METHOD FOR ENHANCING AND SEPARATING BIOPOTENTIAL SIGNALS 未知

    公开(公告)号：CA2285354A1

    公开(公告)日：1999-08-05

    申请号：CA2285354

    申请日：1999-01-25

    Applicant: ASPECT MEDICAL SYSTEMS INC

    Inventor： GREENWALD SCOTT D ,  SMITH CHARLES P ,  DEVLIN PHILIP H

    IPC: A61B5/0476 ,  A61B5/0478 ,  A61B5/0496

    Abstract: Disclosed is an electrode array (i.e., "sensor") and a method for separating near and far-field signals. In one embodiment a horizontal array is used, and in an alternate embodiment a vertical array is used. The electrode array consists of two well-separated pairs of closely spaced electrodes (and a separate ground element). In a typical application of collecting a channel of EEG, "sensing" electrodes are placed in standard locations (e.g., R and Ctr) with a ground electrode placed elsewhere on the head. The voltage measured between the well-separated sensing electrodes is the far-field dominant (i.e., EEG-dominant) channel. Additional electrodes are placed near each of the two sensing electrodes. (The additional electrodes are immediately lateral to the existing electrodes in the horizontal array, and are immediately above the existing electrodes in the vertical array.) The voltages measured between the pairs of closely spaced electrodes are near-field dominant (i.e., EMG/EOGdominant) channels. The EEG, EMG and EOG signals can be enhanced by uncoupling them by combining information from all channels. The sensor is connected to a monitor via a patient interface cable (PIC). The sensor contains additional circuitry at the connection site that is used by the monitor to identify the presence and type of sensor, and to configure the monitor to invoke the appropriate software that will apply the method of the current invention to collect and uncouple the EEG, EMG and EOG.

    8.
    发明专利
    未知

    公开(公告)号：BR0308878A

    公开(公告)日：2005-01-04

    申请号：BR0308878

    申请日：2003-04-01

    Applicant: ASPECT MEDICAL SYSTEMS INC

    Inventor： DAHAN ALBERT ,  GREENWALD SCOTT D

    IPC: A61B5/024 ,  A61B5/0285 ,  A61B5/11 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/16 ,  A61B5/352 ,  A61B5/366 ,  A61M5/00 ,  A61M16/01 ,  A61M21/02

    Abstract: A PTT monitoring system for measuring arousal and responses to stress or pain during sedation or anesthesia. includes ECG electrodes and a PPG probe connected to a computer via signal conditioning and digitizing hardware. Lead I is typically used as the ECG lead while the PPG probe is typically placed on a finger. The ECG and PPG waveforms are continuously analyzed to update and display a current estimate of the subject's PPT from heart to hand. For each cardiac cycle, fiducial points are identified to indicate the pulse onset time (via QRS detection in the ECG) and pulse arrival time (via the point of steepest ascent in the PPG). The onset and arrival times for each cardiac cycle are paired, and the time difference is the interval estimate for that beat. An artifact post-processor (e.g., trim-mean filtering) excludes unlikely intervals from entering the averaged, current estimate of PTT. Finally, the current PTT estimate is displayed numerically and the trend of PTT is updated every second. Clinicians may interpret the instantaneous PTT value directly or in context of its recent trend. If there is a rapid decrease in PTT much less than the predetermined baseline value when the patient should be unconscious and free of stress and pain, then supplemental analgesics are administered to bring PTT greater than or equal to such baseline value.

    9.
    发明专利
    未知

    公开(公告)号：AT247419T

    公开(公告)日：2003-09-15

    申请号：AT97952570

    申请日：1997-12-19

    Applicant: ASPECT MEDICAL SYSTEMS INC

    Inventor： GREENWALD SCOTT D ,  SMITH CHARLES P

    IPC: A61B5/0476

    Abstract: The disclosed filter removes cardiac artifacts from signals representative of a patient's cerebral activity. The filter preferably replaces portions of the signal including artifacts with temporally adjacent artifact free portions.

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