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    BIOADHESIVE COMPOSITIONS AND METHODS OF PREPARATION AND USE
    2.
    发明申请
    BIOADHESIVE COMPOSITIONS AND METHODS OF PREPARATION AND USE 审中-公开
    生物组合物及其制备和使用方法

    公开(公告)号：WO0197872B1

    公开(公告)日：2002-07-25

    申请号：PCT/US0141103

    申请日：2001-06-22

    Applicant: AUSTIN SAM L ,  DAVIS THOMAS E

    Inventor： AUSTIN SAM L ,  DAVIS THOMAS E

    IPC: A61K9/10 ,  A61K31/57 ,  A61K35/12 ,  A61K45/00 ,  A61K47/42 ,  A61K48/00 ,  A61L24/00 ,  A61L24/10 ,  A61L26/00 ,  A61L27/22 ,  A61L31/04 ,  A61P7/04 ,  A61P29/00 ,  C09J189/00

    CPC classification number: A61L31/046 ,  A61L24/0015 ,  A61L24/106 ,  A61L27/225 ,  A61L2300/222 ,  A61L2300/258 ,  A61L2300/402 ,  A61L2300/406 ,  A61L2300/416 ,  A61L2300/418 ,  A61L2300/45 ,  A61L2300/64

    Abstract: The present invention relates generally to the preparation and use of novel enhanced biological tissue adhesives which rely on combining fibrinogen and thrombin. More particularly, the present invention relates to a method of preparing a fibrin sealant whereby said sealant is formed by reconstituting the fibrinogen component in the presence of various critical biological and non-biological agents. The invention further relates to a novel method of using said enhanced fibrin sealant whereby the sealant and accompanying agent are delivered directly to a critical site within the body and sealed in place due to the biostatic quality of the sealant resulting in enhanced therapeutic value derived by the prolonged presence, and optionally time-released delivery, of said accompanying agent at the critical site.

    Abstract translation: 本发明一般涉及依赖于纤维蛋白原和凝血酶的组合的新型增强型生物组织粘合剂的制备和应用。 更具体地说，本发明涉及一种制备纤维蛋白密封剂的方法，其中所述密封剂是通过在各种关键生物和非生物剂的存在下重构纤维蛋白原组分而形成的。 本发明还涉及一种使用所述增强的纤维蛋白密封剂的新方法，其中密封剂和伴随剂直接输送到体内的关键部位并且由于密封剂的生物静态质量而密封在适当位置，导致由 所述伴随剂在关键部位的长时间存在和任选的时间释放递送。

    Radioactive waste disposal cartridge
    8.
    发明申请
    Radioactive waste disposal cartridge 审中-公开
    放射性废物处理盒

    公开(公告)号：WO9610831A3

    公开(公告)日：1996-07-11

    申请号：PCT/US9512783

    申请日：1995-10-02

    Applicant: GENOMYX CORP ,  DAVIS THOMAS E ,  SCHWARTZ HENRY L

    Inventor： DAVIS THOMAS E ,  SCHWARTZ HENRY L

    IPC: G01N27/447 ,  B01J47/12 ,  G01N30/00 ,  G21F9/12

    CPC classification number: G21F9/12 ,  B01J47/133

    Abstract: This invention relates to the use of a unique apparatus and method for extracting radioactive components from liquids, such as electrophoresis buffers. In the present invention, the radioactive liquid is pumped or transported by other suitable means and is passed through a cartridge having an elongated chamber that contains an exchange medium. The exchange medium, i.e. exchange resin, is contained within the elongated chamber between an upper frit and a lower frit. Further, the cartridge has a means within the elongated chamber for retaining pressure between the upper frit and the lower frit. The nucleotides, being charged molecules, bind to the exchange medium and are removed from the liquid. The liquid then exits the cartridge and has such a low amount of radioactivity that it can be disposed of to a conventional drain.

    Abstract translation: 本发明涉及使用从液体如电泳缓冲液中提取放射性成分的独特装置和方法。 在本发明中，放射性液体被其他合适的装置泵送或输送，并且通过具有包含交换介质的细长室的盒。 交换介质，即交换树脂，被包含在上玻璃料和下玻璃料之间的细长室内。 此外，筒具有在细长室内的装置，用于保持上玻璃料和下玻璃料之间的压力。 作为带电分子的核苷酸与交换介质结合并从液体中除去。 液体然后离开墨盒，并且具有如此低的放射性量，使其能够被排放到常规的排水口。

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