公开(公告)号：WO2004016223A2

公开(公告)日：2004-02-26

申请号：PCT/US0325766

申请日：2003-08-15

Applicant: AVENTIS PHARMA INC ,  LI ZHUYIN ,  XIONG JUNJIE ,  SABOL JEFFREY S ,  HU LINGHONG

Inventor： LI ZHUYIN ,  XIONG JUNJIE ,  MA Y HENRY DI ,  SABOL JEFFREY S

IPC: C12Q1/00 ,  A61K20060101 ,  C12N9/99 ,  C12N15/09 ,  C12Q1/533 ,  G01N33/53 ,  A61K

CPC classification number: C12Q1/533 ,  G01N2500/04

Abstract: Provided herein is a novel and useful method for evaluating the ability of compounds or agents to decrease the activity of microsomal prostaglandin E synthase or hematopoietic prostaglandin D synthase to produce their respective prostaglandin products.

Abstract translation: 本文提供了一种用于评估化合物或试剂降低微粒体前列腺素E合酶或造血前列腺素D合成酶以产生其各自的前列腺素产物的活性的能力的新颖且有用的方法。

公开(公告)号：AT437961T

公开(公告)日：2009-08-15

申请号：AT03779081

申请日：2003-09-18

Applicant: AVENTIS PHARMA INC

Inventor： LI ZHUYIN ,  MEHDI SHUJAATH

IPC: C12Q1/48 ,  C12Q1/68

Abstract: Provided herein is a novel and useful method for determining whether a compound or agent decreases or inhibits the activity of a poly(ADP-ribose)-polymerase (PARP).

公开(公告)号：CA2495391A1

公开(公告)日：2004-02-26

申请号：CA2495391

申请日：2003-08-15

Applicant: AVENTIS PHARMA INC

Inventor： MA Y HENRY ,  SABOL JEFFREY S ,  XIONG JUNJIE ,  LI ZHUYIN

IPC: C12Q1/00 ,  A61K20060101 ,  C12N9/99 ,  C12N15/09 ,  C12Q1/533 ,  G01N33/53

Abstract: Provided herein is a novel and useful method for evaluating the ability of compounds or agents to decrease the activity of microsomal prostaglandin E synthase or hematopoietic prostaglandin D synthase to produce their respecti ve prostaglandin products.

公开(公告)号：AU2003258278A1

公开(公告)日：2004-03-03

申请号：AU2003258278

申请日：2003-08-15

Applicant: AVENTIS PHARMA INC

Inventor： XIONG JUNJIE ,  SABOL JEFFREY S ,  MA Y HENRY ,  LI ZHUYIN

IPC: C12Q1/00 ,  A61K20060101 ,  C12N9/99 ,  C12N15/09 ,  C12Q1/533 ,  G01N33/53

Abstract: Provided herein is a novel and useful method for evaluating the ability of compounds or agents to decrease the activity of microsomal prostaglandin E synthase or hematopoietic prostaglandin D synthase to produce their respective prostaglandin products.