公开(公告)号：DE69523072D1

公开(公告)日：2001-11-08

申请号：DE69523072

申请日：1995-12-15

Applicant: AVENTIS PHARMA INC

Inventor： PEET P ,  MEHDI SHUJAATH ,  LINNIK D ,  ANGELASTRO R ,  KIM HWA-OK

IPC: C07D263/06 ,  A61K31/42 ,  A61K31/421 ,  A61K31/535 ,  A61K31/5377 ,  A61K38/00 ,  A61P9/08 ,  A61P9/10 ,  A61P25/00 ,  A61P25/28 ,  A61P43/00 ,  C07D263/04 ,  C07D263/18 ,  C07K5/062

Abstract: This invention relates to oxazolidine inhibitors of calpain and/or cathepsin B and to compositions containing them. As inhibitors of calpain and/or cathepsin B, the compounds are useful in the treatment of patients afflicted with acute or chronic neurodegenerative disorders.

公开(公告)号：DE69523072T2

公开(公告)日：2002-06-20

申请号：DE69523072

申请日：1995-12-15

Applicant: AVENTIS PHARMA INC

Inventor： PEET P ,  MEHDI SHUJAATH ,  LINNIK D ,  ANGELASTRO R ,  KIM HWA-OK

IPC: C07D263/06 ,  A61K31/42 ,  A61K31/421 ,  A61K31/535 ,  A61K31/5377 ,  A61K38/00 ,  A61P9/08 ,  A61P9/10 ,  A61P25/00 ,  A61P25/28 ,  A61P43/00 ,  C07D263/04 ,  C07D263/18 ,  C07K5/062

Abstract: This invention relates to oxazolidine inhibitors of calpain and/or cathepsin B and to compositions containing them. As inhibitors of calpain and/or cathepsin B, the compounds are useful in the treatment of patients afflicted with acute or chronic neurodegenerative disorders.