公开(公告)号：AU6186401A

公开(公告)日：2001-10-18

申请号：AU6186401

申请日：2001-08-17

Applicant: AVENTIS PHARMA INC

Inventor： LINNIK MATTHEW D ,  RACKE MARGARET M ,  KRAKOWSKY JOAN M ,  SUBRAMANIAM ARUN

IPC: C12N15/12

公开(公告)号：AT206413T

公开(公告)日：2001-10-15

申请号：AT95943478

申请日：1995-12-15

Applicant: AVENTIS PHARMA INC

Inventor： PEET NORTON P ,  MEHDI SHUJAATH ,  LINNIK MATTHEW D ,  ANGELASTRO MICHAEL R ,  KIM HWA-OK

IPC: C07D263/06 ,  A61K31/42 ,  A61K31/421 ,  A61K31/535 ,  A61K31/5377 ,  A61K38/00 ,  A61P9/08 ,  A61P9/10 ,  A61P25/00 ,  A61P25/28 ,  A61P43/00 ,  C07D263/04 ,  C07D263/18 ,  C07K5/062

Abstract: This invention relates to oxazolidine inhibitors of calpain and/or cathepsin B and to compositions containing them. As inhibitors of calpain and/or cathepsin B, the compounds are useful in the treatment of patients afflicted with acute or chronic neurodegenerative disorders.

公开(公告)号：ES2165441T3

公开(公告)日：2002-03-16

申请号：ES95943478

申请日：1995-12-15

Applicant: AVENTIS PHARMA INC

Inventor： PEET NORTON P ,  MEHDI SHUJAATH ,  LINNIK MATTHEW D ,  ANGELASTRO MICHAEL R ,  KIM HWA-OK

IPC: C07D263/06 ,  A61K31/42 ,  A61K31/421 ,  A61K31/535 ,  A61K31/5377 ,  A61K38/00 ,  A61P9/08 ,  A61P9/10 ,  A61P25/00 ,  A61P25/28 ,  A61P43/00 ,  C07D263/04 ,  C07D263/18 ,  C07K5/062

Abstract: This invention relates to oxazolidine inhibitors of calpain and/or cathepsin B and to compositions containing them. As inhibitors of calpain and/or cathepsin B, the compounds are useful in the treatment of patients afflicted with acute or chronic neurodegenerative disorders.

公开(公告)号：SI0802909T1

公开(公告)日：2002-02-28

申请号：SI9530539

申请日：1995-12-15

Applicant: AVENTIS PHARMA INC

Inventor： PEET NORTON P ,  MEHDI SHUJAATH ,  LINNIK MATTHEW D ,  ANGELASTRO MICHAEL R ,  KIM HWA-OK

IPC: C07D263/06 ,  A61K31/42 ,  A61K31/421 ,  A61K31/535 ,  A61K31/5377 ,  A61K38/00 ,  A61P9/08 ,  A61P9/10 ,  A61P25/00 ,  A61P25/28 ,  A61P43/00 ,  C07D263/04 ,  C07D263/18 ,  C07K5/062

Abstract: This invention relates to oxazolidine inhibitors of calpain and/or cathepsin B and to compositions containing them. As inhibitors of calpain and/or cathepsin B, the compounds are useful in the treatment of patients afflicted with acute or chronic neurodegenerative disorders.

公开(公告)号：DK0802909T3

公开(公告)日：2002-01-28

申请号：DK95943478

申请日：1995-12-15

Applicant: AVENTIS PHARMA INC

Inventor： PEET NORTON P ,  MEHDI SHUJAATH ,  LINNIK MATTHEW D ,  ANGELASTRO MICHAEL R ,  KIM HWA-OK

IPC: C07D263/06 ,  A61K31/42 ,  A61K31/421 ,  A61K31/535 ,  A61K31/5377 ,  A61K38/00 ,  A61P9/08 ,  A61P9/10 ,  A61P25/00 ,  A61P25/28 ,  A61P43/00 ,  C07D263/04 ,  C07D263/18 ,  C07K5/062

Abstract: This invention relates to oxazolidine inhibitors of calpain and/or cathepsin B and to compositions containing them. As inhibitors of calpain and/or cathepsin B, the compounds are useful in the treatment of patients afflicted with acute or chronic neurodegenerative disorders.

公开(公告)号：PT802909E

公开(公告)日：2002-03-28

申请号：PT95943478

申请日：1995-12-15

Applicant: AVENTIS PHARMA INC

Inventor： PEET NORTON PAUL ,  MEHDI SHUJAATH ,  LINNIK MATTHEW D ,  KIM HWA-OK ,  ANGELASTRO MICHAEL R

IPC: C07D263/06 ,  A61K31/42 ,  A61K31/421 ,  A61K31/535 ,  A61K31/5377 ,  A61K38/00 ,  A61P9/08 ,  A61P9/10 ,  A61P25/00 ,  A61P25/28 ,  A61P43/00 ,  C07D263/04 ,  C07D263/18 ,  C07K5/062

Abstract: This invention relates to oxazolidine inhibitors of calpain and/or cathepsin B and to compositions containing them. As inhibitors of calpain and/or cathepsin B, the compounds are useful in the treatment of patients afflicted with acute or chronic neurodegenerative disorders.

公开(公告)号：NO309267B1

公开(公告)日：2001-01-08

申请号：NO973216

申请日：1997-07-10

Applicant: AVENTIS PHARMA INC

Inventor： PEET NORTON PAUL ,  MEHDI SHUJAATH ,  LINNIK MATTHEW D ,  ANGELASTRO MICHAEL RICHARD ,  KIM HWA-OK

IPC: C07D263/06 ,  A61K31/42 ,  A61K31/421 ,  A61K31/535 ,  A61K31/5377 ,  A61K38/00 ,  A61P9/08 ,  A61P9/10 ,  A61P25/00 ,  A61P25/28 ,  A61P43/00 ,  C07D263/04 ,  C07D263/18 ,  C07K5/062

Abstract: This invention relates to oxazolidine inhibitors of calpain and/or cathepsin B and to compositions containing them. As inhibitors of calpain and/or cathepsin B, the compounds are useful in the treatment of patients afflicted with acute or chronic neurodegenerative disorders.