公开(公告)号：EP1296599A1

公开(公告)日：2003-04-02

申请号：EP01947083.0

申请日：2001-06-22

Applicant: An-Go-Gen Inc.

Inventor： STEWART, Duncan

IPC: A61B17/22 ,  A61B8/12 ,  A61B8/00 ,  A61B8/08

CPC classification number: A61B8/481 ,  A61B8/0833 ,  A61B8/12 ,  A61B17/22012 ,  A61B90/37 ,  A61B2017/00247 ,  A61B2017/22088 ,  A61B2018/00392 ,  A61B2090/378 ,  A61M5/1785 ,  A61M2025/0089

Abstract: An injection catheter is provided with a piezoelectric ultrasound emitting device atits distal end, capable of emitting ultrasound of different energy levels. It can be used toimage the location of penetration of an internal organ of a patient by the catheter needle,by supply of echocontrast material through the needle and analysis of the ultrasoundreflections therefrom. It can also be used to cause tissue perturbation or disruption at theimaged location, e.g. to initiate tissue angiogenesis, by choice of suitable ultrasoundenergy level of emission, and for delivery of therapeutic substances such as DNA to thedisrupted tissue, for better uptake in gene therapy.