公开(公告)号：WO2006135491A3

公开(公告)日：2007-06-28

申请号：PCT/US2006015236

申请日：2006-04-24

Applicant: BASF AG ,  ALI SHAUKAT ,  QUADIR ANISUL

Inventor： ALI SHAUKAT ,  QUADIR ANISUL

IPC: A61K9/00

CPC classification number: A61K31/192 ,  A61K9/7007 ,  A61K9/7015 ,  A61K9/7053 ,  A61K31/135

Abstract: A medicament carrier composition includes a medicament and a polymer component including a polyvinylpyrrolidone having a weight average molecular weight of at least 700,000 g/mol. The medicament carrier composition has a viscosity of from 500 to 5,000 cps at 250C, is substantially free of cellulose, and includes an auxiliary polymer. The medicament carrier composition is used to form a film that is also substantially free of cellulose. The film has a consistent thickness and size, and an increased flexibility and increased moisture resistance due to the polyvinylpyrrolidone. The medicament carrier composition is also used in a method of forming the film. The method includes the steps of providing the medicament and the polymer component. The method also includes the step of combining the polymer component and the medicament to form the medicament carrier composition. The method further includes the step of drying the medicament carrier composition to form the film.

Abstract translation: 药物载体组合物包含药物和包含重均分子量至少为700,000g / mol的聚乙烯吡咯烷酮的聚合物组分。 药物载体组合物在250℃下的粘度为500至5,000cps，基本上不含纤维素，并且包括辅助聚合物。 药物载体组合物用于形成也基本上不含纤维素的膜。 该膜具有一致的厚度和尺寸，以及由于聚乙烯吡咯烷酮而增加的柔性和增加的耐湿性。 药物载体组合物也用于形成膜的方法。 该方法包括提供药物和聚合物组分的步骤。 该方法还包括组合聚合物组分和药物以形成药物载体组合物的步骤。 该方法还包括干燥药物载体组合物以形成膜的步骤。

公开(公告)号：CA2611418A1

公开(公告)日：2006-12-21

申请号：CA2611418

申请日：2006-04-24

Applicant: BASF AG

Inventor： QUADIR ANISUL ,  ALI SHAUKAT

IPC: A61K9/00