公开(公告)号：CA2211109A1

公开(公告)日：1996-08-22

申请号：CA2211109

申请日：1996-02-12

Applicant: BASF AG

Inventor： PFEIFFER THOMAS ,  ZIERKE THOMAS ,  B HM HANS-JOACHIM ,  SEITZ WERNER ,  KOSER STEFAN ,  HORNBERGER WILFRIED ,  H FFKEN HANS WOLFGANG ,  MACK HELMUT

IPC: A61K31/00 ,  A61K38/55 ,  A61P7/02 ,  C07D205/04 ,  C07D207/16 ,  C07D213/53 ,  C07D213/63 ,  C07D213/72 ,  C07D213/78 ,  C07D213/79 ,  C07D239/28 ,  C07D241/14 ,  C07D241/24 ,  C07D401/12 ,  C07K5/06 ,  C07K5/062 ,  C07K5/078 ,  C07J43/00 ,  A61K38/05 ,  C07F7/10 ,  C07D403/12 ,  C07D413/12 ,  C07D417/12 ,  C07D405/14 ,  C07D217/26 ,  A61K31/40 ,  A61K31/435 ,  C07F9/547 ,  C07C255/58 ,  A61K31/58 ,  C07D211/60 ,  A61K31/675 ,  A61K31/695 ,  C07D213/81 ,  C07D213/84

Abstract: The description relates to compounds of formula (I) in which A, B, D, R1 and R2 have the meanings given in the specification. The compounds are suitable for the treatment of diseases. The novel compounds are produced via compounds of the formula H2N-CH2-G-M in which G and M have the meanings given in claim 4.

公开(公告)号：CA2210989A1

公开(公告)日：1996-08-15

申请号：CA2210989

申请日：1996-02-06

Applicant: BASF AG

Inventor： HORNBERGER WILFRIED ,  PFEIFFER THOMAS ,  SEITZ WERNER ,  ZIERKE THOMAS ,  MACK HELMUT ,  H FFKEN HANS WOLFGANG ,  B HM HANS-JOACHIM ,  KOSER STEFAN

IPC: A61K38/55 ,  A61K38/00 ,  A61P7/02 ,  C07K5/06 ,  C07K5/065 ,  C07K5/072 ,  C07K5/087 ,  A61K38/05

Abstract: The invention concerns thrombin inhibitors of formula (I), wherein R1, A, B, and D have the meanings given in the description, and intermediate products for the preparation thereof. The compounds of formula (I) are suitable for combating diseases.