6-Aminophenyl- and 6-Acylaminophenyl-4,5-Dihydropyridazones-(3) and their production

    公开(公告)号:GB1164139A

    公开(公告)日:1969-09-17

    申请号:GB5812266

    申请日:1966-12-29

    Applicant: BASF AG

    Abstract: 1,164,139. Dihydropyridazone derivatives. BADISCHE ANILIN- & SODA-FABRIK A.G. 29 Dec., 1966 [19 Oct., 1966], No. 58122/66. Heading C2C. Novel compounds of formula where R is amino or is acylamino having 2 to 12 C atoms and optionally derived from a polybasic acid, are prepared by reaction of hydrazine with a compound of formula wherein R 11 is OH or alkoxy and R 1 is R or a group convertible to R, and if necessary converting R 1 to R. The novel compounds have anti-inflammatory and blood pressure reducing action.

    8.
    发明专利
    未知

    公开(公告)号:FR1507475A

    公开(公告)日:1967-12-29

    申请号:FR89952

    申请日:1967-01-04

    Applicant: BASF AG

    Abstract: 1,168,291. Pyridazones. BADISOHE ANILIN- & SODA-FABRIK A.G. 6 Jan., 1967, [7 Jan., 1966], No. 925/67. Heading C2C. Novel 6-aminophenyl-3-pyridazones of the Formula I wherein X is a hydrogen or halogen atom or an alkyl or alkoxy group and each of R 1 and R 2 is a hydrogen atom or an alkyl group, any alkyl groups in the substituents being optionally substituted by halogen atoms or hydroxyl groups, are obtained by dehydrogenating the corresponding 6 - aminophenyl - 4,5 - dihydro - 3- pyridazones, in which the radical R 1 may additionally represent an aliphatic or aromatic acyl group, using aromatic nitrosulphonic acids or salts thereof as dehydrogenating agents, the molar ratio of pyridazone to nitrosulphonic derivative being up to 1 : 0À5 per nitro group in the latter.

Patent Agency Ranking