公开(公告)号：DE50011155D1

公开(公告)日：2005-10-20

申请号：DE50011155

申请日：2000-08-10

Applicant: BASF AG

Inventor： ERNST DR ,  KESSLER THOMAS ,  BERNDL DR

IPC: A01N25/10 ,  A01N25/12 ,  A23K40/10 ,  A23K40/20 ,  A23L33/15 ,  A23L33/155 ,  A23P1/02 ,  A61J3/00 ,  A61K9/16 ,  A61K9/19 ,  A61K47/32 ,  B01J2/20 ,  B29B9/06 ,  C08J3/205 ,  C08J3/12 ,  A61K9/20 ,  A61J3/10

Abstract: Production of granules comprising biologically active substances (I) dispersed in a thermoplastic polymer matrix having pH-dependent solubility in aqueous media comprises mixing (I) with the molten matrix material and extruding the melt into a coolant medium in which the granules are not soluble or dispersible An Independent claim is also included for granules produced by the process.

公开(公告)号：DE59809317D1

公开(公告)日：2003-09-25

申请号：DE59809317

申请日：1998-04-23

Applicant: BASF AG

Inventor： KOTHRADE DR ,  MEFFERT DR ,  BERNDL DR ,  SANNER DR ,  STEIN DR ,  SCHEHLMANN DR ,  RUCHATZ DR

IPC: A61K8/72 ,  A61K8/00 ,  A61K8/81 ,  A61K47/14 ,  A61K47/30 ,  A61K47/32 ,  A61Q19/00 ,  C09K23/32 ,  C09K23/52

Abstract: The use of N-vinyl-pyrrolidone (NVP) copolymers (I) is claimed as surfactants in formulations of water-insoluble materials (II). (I) is derived from (a) 60-99 mol.% NVP, (b) 1-40 mol.% of one or more monomer(s) selected from (b1) 8-30C alkyl esters of mono-ethylenically unsaturated 3-8C carboxylic acids, (b2) N-(8-18C alkyl)- or N,N-di-(8-18C alkyl)-substituted (meth)acrylamides and (b3) vinyl esters of 8-30C aliphatic carboxylic acids and (c) 0-39 mol.% of further radically copolymerisable monomers. The (II) formulations containing (I) as surfactant are also claimed.